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significant changes » significant challenge (Expand Search)
changes decrease » largest decrease (Expand Search), change increases (Expand Search)
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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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17981
Supplementary file 3_Protective and risk factors in daily life associated with cognitive decline of older adults.docx
Published 2025“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.…”
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17982
Supplementary file 2_Protective and risk factors in daily life associated with cognitive decline of older adults.docx
Published 2025“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.…”
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17983
Alcohol perceptions and driving decisions among adolescents: Exploring the role of peer and parental influences in Virginia
Published 2025“…Though parent distracted driving positively influenced adolescent driving behavior, this effect was not statistically significant (coefficient = 0.008, <i>P</i> = .320).</p> <p>The findings indicate a significant reduction in risky behaviors such as drinking and driving and an increase in seat belt use among adolescents. …”
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17984
Data Sheet 1_Successional patterns of microbial communities across various stages of leaf litter decomposition in poplar plantations.pdf
Published 2025“…With the decomposition of leaf litter, the total N content increased gradually, while other nutrients (C, P, K, cellulose and hemicellulose) decreased progressively. Litter characteristics had significant effects on microbial community structure: C/N, TK and residual hemicellulose (RH) were the primary driving factors affecting fungal community structure, whereas bacterial community structure was influenced by TK, RH, residual cellulose (RC) and lignin contents.…”
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17985
GPCR kinase, <i>Ppa</i>-GRK-2 is required for light avoidance.
Published 2024“…<i>Ppa-grk-2</i> mutants had decreased light avoidance. One-way ANOVA, Dunnett’s multiple comparison tests, compared with wild type. n.s = not significant, ***<i>P</i> < 0.001, ****<i>P</i> < 0.0001.…”
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17986
Figure 1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
Published 2025“…<b>F,</b> Under hypoxia (3% O<sub>2</sub>), OCR ablation was observed at 1 µmol/L atovaquone and while a trend toward reduced OCR was observed for banoxantrone this was not significant.…”
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17987
PVD neurons show reduced lysosome function during aging and in the <i>hlh-30</i> mutant.
Published 2025“…<p><b>(A–D)</b> A fluorescent reporter for luminal acidity of neuronal lysosomal compartments shows that acidity decreases with aging and in the <i><i>hlh-30</i></i> mutant. …”
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17988
Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”
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17989
Table 2_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”
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17990
Table 1_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.docx
Published 2025“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”
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17991
Table 3_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx
Published 2025“…Implementing upstream processes in a chemically defined media in stirred-tank bioreactors (STBr) is mandatory to closely control the cell environment, and to scale-up production, but it remains a significant challenge for anchorage-dependent cells.…”
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17992
Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation.
Published 2025“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”
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17993
Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
Published 2025“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”
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17994
Routine blood biochemical biomarkers in amyotrophic lateral sclerosis: Systematic review and cohort analysis
Published 2024“…To provide further information about the roles of these four biomarkers roles we performed a systematic review. In addition, we also performed a new study of the role of these biomarkers in predicting survival, using data from our local ALS cohort. …”
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17995
Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Published 2025“…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …”
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17996
Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Published 2025“…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …”
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17997
Data Sheet 1_Effect of Medicaid accountable care on preventable emergency department and hospital admissions: rural-urban heterogeneity.pdf
Published 2025“…</p>Results<p>The CCO model was associated with reductions of 25 all-cause ED visits and 22 preventable ED visits per 1,000 persons per month during the first three years. Significant decreases in all-cause and preventable ED visits were observed across different levels of rurality. …”
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17998
Effects of liposomal bupivacaine (LB) and provider experience with LB on service utilization, clinical outcomes, and Medicare expenditures among fee-for-service (FFS) beneficiaries
Published 2025“…</p> <p></p><p>Liposomal bupivacaine (LB) represents a significant advancement in postoperative pain management, with studies demonstrating its ability to reduce opioid consumption and improve recovery outcomes. …”
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17999
Table 1_Forest bathing enhances sleep, mood, and immunity: insights from low-latitude evergreen broad-leaved forests.xlsx
Published 2025“…Serum AQP9 and HSPA6 levels decreased, while salivary IgA and lysozyme surged.</p>Discussion<p>These findings suggest forest bathing offers immediate and multidimensional health benefits, highlighting its potential as a non-pharmacological intervention for holistic well-being. …”
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18000
The effect of cognitive behavioral therapy-based psychoeducation on substance abuse proclivity in adolescent smokers
Published 2025“…</p> <p>The study is an experimental study model with pretest–posttest control group. As a result of the power analysis carried out for the sample of the study, the sample size was calculated to be 110 adolescent smokers at a significance level of 0.05, confidence interval of 95%, an effect size of 0.7, and power of population representation of 0.95. …”