يعرض 1,581 - 1,600 نتائج من 2,227 نتيجة بحث عن '(( significantly ((larger decrease) OR (largest decrease)) ) OR ( significantly impair decrease ))', وقت الاستعلام: 0.49s تنقيح النتائج
  1. 1581

    Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…Since, non-synaptic mitochondria displayed a significantly reduced ss[Ca<sup>2+</sup>]<sub>e</sub>, this suggested a larger mCa<sup>2+</sup> buffering capacity to maintain [Ca<sup>2+</sup>]<sub>m</sub> with increasing mCa<sup>2+</sup> loads. …"
  2. 1582

    Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif حسب Jyotsna Mishra (3703195)

    منشور في 2025
    "…Since, non-synaptic mitochondria displayed a significantly reduced ss[Ca<sup>2+</sup>]<sub>e</sub>, this suggested a larger mCa<sup>2+</sup> buffering capacity to maintain [Ca<sup>2+</sup>]<sub>m</sub> with increasing mCa<sup>2+</sup> loads. …"
  3. 1583

    Improved estimation of soil organic carbon stock in subtropical cropland of Southern China based on digital soil mapping and multi-sources data حسب Bifeng Hu (3778951)

    منشور في 2025
    "…Additionally, the mean value of SOCD significantly decreased from 3.23 in the 1980s to 2.95 kg m<sup>−2</sup> in the 2010s. …"
  4. 1584

    Data Sheet 1_Improving tea quality and fruit yield through intercropping with climbing plants.pdf حسب Qing Liao (1466149)

    منشور في 2025
    "…Tea polyphenol content decreased with increasing density, most notably in PE-H (−21.63% vs. …"
  5. 1585

    Dataset. حسب Valéria Teresa Saraiva Lino (20390441)

    منشور في 2024
    "…In the intervention group, there was a significant decrease in the likelihood of violence against the elderly, with a 10-fold reduction. …"
  6. 1586

    CONSORT flow diagram. حسب Valéria Teresa Saraiva Lino (20390441)

    منشور في 2024
    "…In the intervention group, there was a significant decrease in the likelihood of violence against the elderly, with a 10-fold reduction. …"
  7. 1587

    Figure 5 from Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma حسب Marianna Carrabotta (8193039)

    منشور في 2025
    "…The repression of MAPK signaling by the CIC-DUX4 fusion protein renders CDSs mainly dependent on the AKT/mTOR pathway. Trabectedin can impair HMGA2 activity by preventing its binding to promoters, thus inhibiting the transcription of its targets <i>IGF2BP2</i> and <i>IGF2BP3</i> and decreasing IGF2/IGF1R signaling. …"
  8. 1588

    Presentation 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

    منشور في 2025
    "…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"
  9. 1589

    Presentation 3_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

    منشور في 2025
    "…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"
  10. 1590

    Data Sheet 1_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... حسب Gyeong Ho Baek (21382907)

    منشور في 2025
    "…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"
  11. 1591

    Data Sheet 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibi... حسب Gyeong Ho Baek (21382907)

    منشور في 2025
    "…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"
  12. 1592

    Presentation 2_A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhi... حسب Gyeong Ho Baek (21382907)

    منشور في 2025
    "…</p>Results<p>NuGel (0.3% [Nu0.3] and 0.5% [Nu0.5]) was well-tolerated, with no adverse drug reactions or serious adverse events. Nu0.3 showed a significant decrease in EASI score from baseline (-12.2%, [-30.3%, 5.9%], p = 0.04). …"
  13. 1593

    Table 1_Microplastics in focus: a silent disruptor of liver health- a systematic review.docx حسب Zahra Beyzaei (9911886)

    منشور في 2025
    "…., increased serum cysteine, decreased hepatic cysteine, and disturbed homocysteine metabolism), impair mitochondrial bioenergetics, and lead to significant lipid accumulation after exposures lasting up to 500 h. …"
  14. 1594

    Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> حسب Meng-Ru Guo (21375491)

    منشور في 2025
    "…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …"
  15. 1595

    Supplementary file 2_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx حسب Teame Gereziher Mehari (11253141)

    منشور في 2025
    "…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. …"
  16. 1596

    Supplementary file 1_Histopathological examination and transcriptomic profiling reveal gossypol toxicity-responsive genes related to fertility in mice.docx حسب Teame Gereziher Mehari (11253141)

    منشور في 2025
    "…Introduction<p>Gossypol impairs reproduction in both sexes, inducing mitochondrial dysfunction, irregular cycles, and fewer ovarian follicles, leading to decreased fertility rates. …"
  17. 1597

    Epidemiological analysis of SARS-CoV-2 variants in Saudi Arabia حسب Mohamed A. Farrag (22769757)

    منشور في 2025
    "…The first wave occurred in June 2020, the second wave occurred in July 2021, and the largest wave occurred in January 2022. Our findings also revealed that after vaccination against COVID-19 was introduced, the number of deaths per month significantly decreased. …"
  18. 1598

    Table 3_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx حسب Inês Carvalho (59935)

    منشور في 2025
    "…These findings, together with the lower mRNA expression of proinflammatory genes in the head kidney and the higher mortality rates observed in this group, suggest a potential impairment of the immune response.`</p>Discussion<p>Overall, these findings indicate that dietary methionine supplementation may significantly influence both systemic and local immune responses in European seabass, highlighting the need for careful consideration when supplementing diets with methionine.…"
  19. 1599

    Table 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.xlsx حسب Chen Chen (6544)

    منشور في 2025
    "…<p>Impaired intestinal epithelial barrier function is closely associated with the pathogenesis of ulcerative colitis (UC). …"
  20. 1600

    Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif حسب Chen Chen (6544)

    منشور في 2025
    "…<p>Impaired intestinal epithelial barrier function is closely associated with the pathogenesis of ulcerative colitis (UC). …"