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significantly observed » significantly bolstered (Expand Search), significantly altered (Expand Search), significantly clustered (Expand Search)
larger decrease » marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
significantly observed » significantly bolstered (Expand Search), significantly altered (Expand Search), significantly clustered (Expand Search)
larger decrease » marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
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5721
Data Sheet 3_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5722
Presentation 1_Deficits in medial prefrontal cortex parvalbumin expression and distraction-dependent memory in rats and mice in the sub-chronic phencyclidine model for schizophreni...
Published 2025“…These CIAS may partly result from decreased expression of parvalbumin (PV) in medial prefrontal cortex (mPFC) interneurons. …”
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5723
Table 1_Forest bathing enhances sleep, mood, and immunity: insights from low-latitude evergreen broad-leaved forests.xlsx
Published 2025“…Routine blood tests, lymphocyte subset profiling, and immune markers (Aquaporin 9 (AQP9), Heat Shock Protein A6 (HSPA6), salivary immunoglobulin A (IgA) (salivary IgA), and lysozyme) were measured immediately, one week, and one month post-intervention.</p>Results<p>Significant improvements were observed across multiple domains. …”
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5724
Data Sheet 4_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5725
Data Sheet 5_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5726
Data Sheet 6_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5727
Dynamic Regulation of Proton and Water Transport through an Acylhydrazone-Based Photoresponsive Channel
Published 2025“…A similar trend was observed in water transport, where the single-channel permeability of <b>1a</b> increased from 6.5 × 10<sup>6</sup> to 3.5 × 10<sup>7</sup> water molecules/s/channel upon switching from the <i>E</i> to <i>Z</i> isomers, then decreased to 1.8 × 10<sup>7</sup> after reverting to the <i>E</i> conformer. …”
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5728
Data Sheet 2_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5729
Data Sheet 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5730
Table 6_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.docx
Published 2025“…West Africa, North Europe, and North America saw rising prevalence rates, while East Asia showed a declining trend. A decreasing trend is observed in most countries and regions worldwide, particularly in East Asia, with projections suggesting a continued decline in the future.…”
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5731
Data Sheet 1_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont...
Published 2025“…No increase in adverse events was observed when TXL was added to WM [RR 1.02, 95% CI (0.70, 1.49); NNT = 149].…”
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5732
Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx
Published 2025“…The most notable increases were observed in Eastern Europe. By stroke subtype, metabolic risk factors contributed to 1,147,521 DALYs from ischemic stroke, 2,267,874 from intracerebral hemorrhage, and 544,954 from subarachnoid hemorrhage in 2021. …”
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5733
Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf
Published 2025“…The immune response alterations observed in the MCAO/R group were consistent with the trends indicated by stroke patient data.…”
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5734
Data Sheet 1_The role of oxidative stress in modulating mortality risk across the hypertension control cascade.docx
Published 2025“…Q1, HR: 0.82; 95% CI: 0.66–0.87; P < 0.001). A significant interaction was observed between OBS and hypertension control status (P for interaction = 0.017 and 0.026), corroborated by sensitivity analyses (P for interaction = 0.025). …”
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5735
Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d...
Published 2025“…</p>Results<p>Our findings revealed that OB EVs induced significant phosphorylation of STAT3, a key signaling molecule in cancer progression, and promoted increased cell migration, dependent on fatty acid oxidation (FAO). …”
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5736
Table 5_Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activa...
Published 2025“…Additionally, increased expression of the NLRP3 inflammasome, Caspase-1, GSDMD, and the pro-inflammatory cytokines IL-1β and IL-18 was observed. Multi-omics analysis revealed significant enrichment in lipid metabolic pathways, with Fasn identified as a hub gene. …”
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5737
Table 1_Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis.docx
Published 2025“…For other outcomes, including gestational diabetes mellitus, ectopic pregnancy, placental abruption, placenta previa, large and small for gestational age, preterm birth, high and low birth weight, perinatal death, stillbirth, neonatal death, and congenital anomalies, no significant disparities were observed.</p>Conclusions<p>Donor sperm offers improved pregnancy outcomes for severe male infertility or paternally inherited genetic disorders but is linked to elevated risks of preeclampsia and pregnancy-induced hypertension. …”
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5738
Supplementary Material for: Efficacy of penetrating canaloplasty versus trabeculectomy in patients with bilateral primary glaucoma: a self-control study
Published 2025“…Although not statistically significant, higher qualified success was observed in TRAB (96.0%) than in PCP group (88.0%, p=0.609) at 12 month. …”
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5739
Image 3_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg
Published 2025“…No statistically significant differences were observed in pulmonary mechanics between male mice with or without conditional loss of epithelial cell Bdnf, although treatment effects of IL-13 were noted. …”
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5740
Data Sheet 1_Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19.pdf
Published 2025“…Among the biomarkers indicative of macrophage polarization, compared to non-ARDS patients, a significant increase in IL-10, Inducible nitric oxide synthase (iNOS), and Arginase-1 (Arg-1) were observed in ARDS patients, while Tumor necrosis factor-α (TNF-α) was decreased. …”