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1701
Table 4_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1702
Image 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.tif
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1703
Table 2_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1704
Table 1_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1705
Table 3_Analysis of global trends in acute lymphoblastic leukemia in children aged 0–5 years from 1990 to 2021.docx
Published 2025“…</p>Findings<p>Between 1990 and 2021, the global number of childhood ALL cases increased by 59.06%, reaching 168,879 cases in 2021, while ALL-related deaths and DALYs decreased by 66.71% and 66.13%, respectively. High- and high-middle SDI regions demonstrated significant improvements, driven by advances in healthcare and early diagnosis. …”
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1706
DataSheet1_Efficacy and safety of danshen class injections in the treatment of coronary heart disease: a network meta-analysis.docx
Published 2024“…The results of NMA showed that, XD injection significantly enhances clinical efficacy; STS is more effective in reducing hs-CRP levels; DSDFSY shows better efficacy in decreasing IL-1 and increasing NO levels; DSCXQ has a greater advantage in reducing IL-6 levels; GXN is more effective in regulating SOD levels; and DH is better at reducing MDA levels.…”
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1707
Association of COL4A2 indel polymorphism with the development of stomach adenocarcinoma in Chinese populations
Published 2024“…Logistic regression analysis revealed that both the heterozygote and homozygote 4-bp del/del genotypes were significantly associated with a decreased risk of STAD, even after controlling for other variables (adjusted odds ratio [OR] = 0.663, 95% confidence interval [CI] 0.519–0.848, <i>p</i> = 0.037; OR = 0.422, 95% CI 0.290–0.614, <i>p</i> = 0.000005, respectively). …”
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1708
Rinderine suppresses African swine fever virus replication in porcine alveolar macrophages by dual targeting of membrane-associated profilin 1 and phosphatidylethanolamine
Published 2025“…<p>African swine fever (ASF) is a highly contagious disease caused by African swine fever virus (ASFV), posing a serious threat to the global pig industry. Natural small molecules have been reported to exhibit anti-ASFV potential. …”
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1709
AgTL2 embryos have altered lipids, metabolites, and transcriptional profiles during development.
Published 2024“…(C) Heatmap of metabolites analyzed by LC-MS showing levels of the 60 most highly dysregulated metabolites in AgTL2 embryos compared to controls throughout development (values of <i>t</i> test statistic, range: blue to red = significant decrease to increase) (3 biological replicates represented by triplicate columns at each time point). …”
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1710
Table 1_Impact of the Yangtze River on Sediment source-to-sink processes in estuarine bays: a study of the Oujiang River Estuary, SE China.docx
Published 2025“…In conclusion, our study underscores the significant influence of sediments from the Yangtze River on the surface sediments in small mountain rivers and offshore regions near the Zhejiang coastline.…”
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1711
Supplementary Material for: Impact of Ketogenic Diet on Weight, Metabolic, and Endocrine Parameters in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Published 2025“…Moreover, LH concentrations were significantly reduced (SMD 1.12 ng/dL [0.39, 1.84] p=0.003), FSH levels raised (SMD -0.76 ng/dL [-1.25, -0.28], p=0.002), the LH/FSH ratio decreased (SMD 2.04 (95% CI 1.04-3.03, p<0.001); testosterone decreased (free-T SMD 0.57 ng/dL [95% CI 0.28, 0.86], p<0.001; total-T SMD 0.54 ng/dL, 95% CI 0.28, 0.80, p<0.001), and SHBG levels were significantly increased (SMD 0.79, 95% CI [1.24-0.34],p<0.001). …”
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1712
Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg
Published 2024“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”
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1713
Data Sheet 1_Do you speak cat? Assessing the impact of a training video on human recognition of cat emotions and behaviours during play interactions.pdf
Published 2025“…Previous vocational cat experience was associated with higher accuracy in negative interactions. Training had a small but significant positive impact on overall performance but paradoxically significantly decreased subtle negative behaviour recognition. …”
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1714
Image 2_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg
Published 2024“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”
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1715
Data Sheet 1_CRIF1 gene therapy ameliorates inflammatory bowel disease by suppressing TH17 cells and fibrosis through mitochondrial function regulation.pdf
Published 2025“…Although serious modifications of the tissue architecture of the small intestine have been reported in CRIF1-deficient mice, how this may affect the development of inflammatory bowel disease (IBD) remains unclear. …”
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1716
<b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b>
Published 2024“…SZC-6 shows promise as a small-molecule compound for promoting diabetic wound healing.…”
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1717
Image 1_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg
Published 2024“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”
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1718
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
Published 2025“…</p><p dir="ltr">Our results suggest that the increase in cytosolic Ca<sup>2+</sup> elicited by HlyA impacts RBCs’ circulation by decreasing RBCs’ deformability and increasing spleen retention. …”
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1719
Data Sheet 1_Using a co-created checklist to improve on-farm biosecurity: an observational pilot intervention with pig farmers and livestock field officers in Sumbawanga, Tanzania....
Published 2025“…<p>The Tanzanian pig sector has the capacity to become market-oriented but it is constrained by significant factors like poor husbandry, management practices and disease, like African swine fever (ASF). …”
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1720
Supplementary Material for: Atypical COVID-19-related Acute Macular Neuroretinopathy with Progression resulting in Severe Vision Loss
Published 2024“…Examination of the fundus was remarkable for small flame-shaped hemorrhages in the superior arcade of both eyes. …”