Search alternatives:
significant large » significantly larger (Expand Search), significant change (Expand Search), significant larval (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increases » increased (Expand Search), increase (Expand Search)
significant large » significantly larger (Expand Search), significant change (Expand Search), significant larval (Expand Search)
larger decrease » marked decrease (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increases » increased (Expand Search), increase (Expand Search)
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Directed Evolution of a Plant Glycosyltransferase for Chemo- and Regioselective Glycosylation of Pharmaceutically Significant Flavonoids
Published 2021“…Combining an alanine scan and iterative saturation mutagenesis, mutants with enhanced chemo- and regioselectivity and significantly improved activities toward seven different flavonoids were evolved, and two glycosylated products were prepared on a large scale. …”
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Directed Evolution of a Plant Glycosyltransferase for Chemo- and Regioselective Glycosylation of Pharmaceutically Significant Flavonoids
Published 2021“…Combining an alanine scan and iterative saturation mutagenesis, mutants with enhanced chemo- and regioselectivity and significantly improved activities toward seven different flavonoids were evolved, and two glycosylated products were prepared on a large scale. …”
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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Select micrographs of placentae with features of reduced villous maturity and increased vascularity.
Published 2023Subjects: -
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Spatial information of excitatory neurons in APP/PS1 mice are decreased in dCA1 and vCA1.
Published 2024“…The spatial information in dCA1 was significantly larger than circularly shuffled spike trains with similar mean firing rates for C57BL/6 mice (mean ± std: empirical = 0.134 ± 0.050, shuffled = 0.123 ± 0.035, p < 0.005, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 229 units from 5 recording sessions, n<sub>shuffled</sub> = 22900 simulated units from 5 recording sessions), but not for APP/PS1 mice (mean ± std: empirical = 0.132 ± 0.054, shuffled = 0.124 ± .054, p = 0.13, two-sided Wilcoxon rank-sum test, n<sub>empirical</sub> = 124 units from 4 recording sessions, n<sub>shuffled</sub> = 12400 simulated units from 4 recording sessions). …”
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