Small-Molecule Inhibitors of Tankyrases as Prospective Therapeutics for Cancer by Mingfeng Yu (591016)

“…Accordingly, tankyrase inhibitors have gained increasing attention as potential therapeutics. Since the discovery of XAV939 and IWR-1 as the first tankyrase inhibitors over two decades ago, tankyrase-targeted drug discovery has made significant progress. …”

Syndecan 3 expression in the porcine small intestine. by Shiu-Jau Chen (21077803)

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”

Overexpression of <i>srgA</i> increases survival 100-fold. by Manon Janet-Maitre (14504859)

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Supplementary Material for: Increased Premature Cerebral Small Vessel Diseases in Dialysis Patients: A Retrospective Cross-Sectional Study by Zheng K. (5999387)

“…<b><i>Results:</i></b> Compared with controls, the prevalence of CSVD was significantly increased in dialysis patients (odds ratio [OR] 2.66, 95% confidence interval [CI] 1.26–5.62). …”

Analysis of the activity of tight junction protein in the small intestine in the mice. by Limin Liu (201430)

Loss of Olfm4⁺ stem cells and increased Paneth cells in small intestine of NDD mice. by Quanhui Dai (9461196)

Nasal microbiota features significantly associate with the presence of clinical signs. by Holly Kristin Arnold (14204655)

Gut microbiota features significantly associate with the presence of clinical signs. by Holly Kristin Arnold (14204655)

Significant differences in monthly mean temperature [°C] between 7ka BP and PI, simulated by MPI-ESM. by Fabian Kirsten (17310195)

Exposure to biologics during pregnancy does not affect placental antibody transfer of anti-SARS-CoV-2 neutralizing antibodies, but concomitant corticosteroid exposure may decrease... by Donna E. Leet (22772478)

Mean apparent diffusion coefficients and their changes during treatment in small ROIs. by Erikka Holopainen (15453568)

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PD-1 deficiency does not significantly impact the pathogen load and pathology following <i>S</i>. <i>japonicum</i> infection. by Liaoxun Lu (179293)

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Operational definitions for small vessel disease and sudden sensorineural hearing loss selected in our study. by Chul Young Yoon (16970190)

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Summary of metabolites with statistically significant association with mortality at 6 months. by Aleksi J. Nummela (18764801)

Transcriptional analysis reveals increased OXPHOS in RTS osteoblasts. by Brittany E. Jewell (11886281)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

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Increased sexual dimorphism in dense populations of Olive-backed Sunbirds on small islands: morphological niche contraction in females but not males by Darren P. O’Connell (6495773)

“…Here we investigate sexual dimorphism in morphological niche of Olive-backed Sunbird populations in South-east Sulawesi, Indonesia. We found decreased overlap in morphological niche between females and males on the species-depauperate Wakatobi Islands, in comparison to mainland Sulawesi and its larger continental islands, indicating greater sexual dimorphism on the small islands. …”

Significant differences in monthly mean precipitation [mm/mon] between 7ka BP and PI, simulated by MPI-ESM. by Fabian Kirsten (17310195)

Significant differences in monthly mean soil moisture between 7ka BP and PI [mm], simulated by MPI-ESM. by Fabian Kirsten (17310195)