PD-1-deficient T cells dramatically outcompete wildtype T cells <i>in vivo</i> in the absence of natural Tregs during chronic <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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PD-1 deficiency suppresses Th2 differentiation and promotes IFN-γ production in liver T cells of the <i>S</i>. <i>japonicum</i> infected mice. حسب Liaoxun Lu (179293)

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PD-1 deficiency does obviously not change B cell and CD11b⁺ myeloid cell IHC staining in livers following <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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PD-1-deficient Tregs suppresses CD4⁺ T cell expansion upon TCR stimulation <i>in vitro</i>. حسب Liaoxun Lu (179293)

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T cell purification and Treg depletion for <i>in vitro</i> TCR stimulation using WT and PD-1-deficient <i>Pdcd1</i>^{<i>−/−</i>} mice. حسب Liaoxun Lu (179293)

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Foxp3 expression in wildtype mice with 8 weeks of <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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PD-1 induction in liver and spleen T cells during early stage of <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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Excessive expression of immunosuppressive receptors by PD-1-deficient regulatory T cells. حسب Liaoxun Lu (179293)

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PD-1 expression induced in CD4⁺ and CD8⁺ T cells by <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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Regulatory T cells are not obviously induced during early phase of <i>S</i>. <i>japonicum</i> infection in C57BL/6 WT mice. حسب Liaoxun Lu (179293)

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Antibodies and fluorescent dyes used for flow cytometric analysis in this study. حسب Liaoxun Lu (179293)

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PD-1 deficiency robustly boosts regulatory T cells and inhibit T cell activation in <i>S</i>. <i>japonicum</i> infected mice. حسب Liaoxun Lu (179293)

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PD-1-deficient CD45.2⁺ Tregs are more competitive than WT CD45.2⁺ Tregs in suppressing CD45.1⁺ conventional CD4 T cells following TCR stimulation <... حسب Liaoxun Lu (179293)

الموضوعات:

Proliferation of T cells from WT and PD-1-deficient <i>Pdcd1</i>^{<i>−/−</i>} mice following <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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mRNA expression of Th2 cytokines in splenic T cells of wildtype mice with or without <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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Unisex schistosome infection and PD-1 expression in liver T cells. حسب Liaoxun Lu (179293)

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T cells in spleens and livers of WT and PD-1-deficient mice in steady state. حسب Liaoxun Lu (179293)

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Frequencies of T cells and myeloid cells in the liver of WT and PD-1-deficient mice with or without <i>S</i>. <i>japonicum</i> infection. حسب Liaoxun Lu (179293)

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S1 Data - حسب Liaoxun Lu (179293)

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T cell count in CD45.1⁺ <i>CD3e</i>^−/− recipient mice after adoptive transfer of T cells (with Tregs) from WT and PD-1-deficient mice and <i>S</i>. <i>japonic... حسب Liaoxun Lu (179293)

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