Data Sheet 1_Trends in lower extremity peripheral arterial disease incidence since 1990 and forecasting future statistics using Global Burden of Disease 2021: a time-series analysi... by Jiacheng Li (826240)

“…Background<p>Lower extremity peripheral arterial disease (LEPAD) significantly affects quality of life and is associated with severe cardiovascular risks. …”

Table 3_Short-term effects of clown visits in child and adolescent psychiatric care: a pilot study on patient stress and mood outcomes and staff evaluations.docx by Amos-Silvio Erik Friedrich (21346907)

“…</p>Results<p>Self-reported stress levels of children and adolescents were decreased significantly from before to after clown visits, whereas salivary cortisol indicated a similar, but nonsignificant decrease. …”

Management of asthma exacerbations in pediatric emergency departments across the United States by Melisa S. Tanverdi (17948353)

“…Most (74.9%) encounters resulted in ED discharge with a downward trend of visits for exacerbations per 1,000 ED visits of −9.77, 95% CI [–9.99,-9.54], increase in disposition to intensive care unit of 2.01 [1.87,2.41] and decrease in home/other of −3.77 [–4.34,–3.20]. There was no significant trend in return visits. …”

Image 5_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”

Data Sheet 3_Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study.csv by Po-Chun Liu (676035)

“…Additionally, we identified an increase in the ARGORNPROST-PWY pathway (L-arginine degradation, q = 0.003) and a decrease in the PWY-6478 pathway (GDP-D-glycero-α-D-manno-heptose biosynthesis, q = 0.015) in MSA patients compared with HCs.…”

Supplementary file 1_The interaction between obesity and sex alters the response to house dust mite in an experimental model of allergic lung inflammation.docx by Amanda Santos-Cavalcante (22288645)

“…Additionally, it has been demonstrated that obesity is a significant predisposing factor for asthma, particularly among women. …”

Table_4_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc by Sofia Priyadarsani Das (17830028)

“…The diet containing L. acidophilus at 1 × 10⁷ CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. Moreover, it upregulated several physiological pathways such as carbohydrate metabolism, signal transduction, lipid metabolism, nucleotide metabolism, amino acid metabolism, and environmental adaptation, which led to the upregulation of the AMPK, MAPK, P13K-Akt, lysosome, peroxisome, and ferroptosis signaling pathways; this enhanced growth and immunity in white shrimp. …”

Data Sheet 1_Vespa orientalis pupae peptide hydrolysates modulate NF-κB signaling in LTA-induced pneumonia from clinical Enterococcus faecalis isolates: implications for gut microb... by Mujeeb Ur Rahman (20445245)

“…Introduction<p>Pneumonia continues to be a significant infectious disease, marked by ongoing lung inflammation, breathing difficulties, and high mortality rates, especially among young children in low-income nations.…”

Image 3_Pharmacokinetics of cannabidiol and its two main phase I metabolites in Connemara ponies.tiff by Kata Wermer (21614717)

“…</p>Results<p>The CBD oil was well-tolerated, with no side effects. A significant decrease in heart rate was observed after 24 h. …”

Table 4_Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum.xlsx by Inês Carvalho (59935)

“…</p>Results<p>While higher methionine intake reduced hemoglobin levels, no other significant changes in the immune status were observed. …”

Table 1_Muscle quality index and hyperuricemia: adipose tissue as a mediator.docx by Ya Shao (16975896)

“…Each one-unit increment in MQI corresponded to a 50% decrease in the odds of hyperuricemia (OR: 0.50, 95% CI: 0.43–0.57). …”

Table 1_Burden of malignant neoplasm of bone and articular cartilage from 1990 to 2021 and its predictions to 2030 in China compared with world.docx by Cheng Chen (136164)

“…The burden prediction for MNBAC to 2030 showed that China would experience a more significant drop in incidence and mortality rates for MNBAC, along with a decrease in the incidence and mortality cases.…”

Image 9_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”

Image 3_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Image 2_Pharmacokinetics of cannabidiol and its two main phase I metabolites in Connemara ponies.tiff by Kata Wermer (21614717)

“…</p>Results<p>The CBD oil was well-tolerated, with no side effects. A significant decrease in heart rate was observed after 24 h. …”

Mean GHQ scores (2019- September 2021). by Mhairi Webster (20454888)

“…Loneliness accounted for a share of the mental health gender gap, and a more decrease in mental health was recorded for young women experiencing loneliness, compared to older age groups. …”

Datasheet1_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studi... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Table 1_Impact of repeated in-vitro bacterial culture on virulence and antibiotic resistance characteristics: a study of Gram-positive and Gram-negative fish pathogens.docx by Angana Bag (21398267)

“…The results revealed a significant decrease in the virulence of Gram-positive pathogens. …”

Altered photoreceptor fate specification in TET mutant retinas. Related to Fig 3. by Ismael Hernández-Núñez (10128242)

“…<b>(B)</b> Graphs showing the significant decrease in the number of photoreceptor cell nuclear layers in the ONL comparing Cre−, tHet, and Tet tcKO H&E-stained retinas both at P21 and 6 weeks. …”

Image 1_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”