Data Sheet 1_Plasma testosterone concentration is correlated with circulating immune cell abundance in transgender young people on gender-affirming hormone treatment.pdf by Alice A. White (21695726)

“…<p>Sex hormones, such as oestrogen and testosterone, display significant immune modulatory properties. This is highly relevant for transgender (trans) people who undergo gender-affirming hormone (GAH) treatment. …”

Chromosomal partitioning is maintained during intracellular UPEC coccobacilli divisions. by Alaska Pokhrel (9566813)

“…<b>i</b>, FtsZ-mNeonGreen (green) rings do not constrict over unsegregated chromosomes (HupA-RFP, pseudo-coloured magenta) in extracellular rods. Statistical significance was determined by student <i>T</i> test, where **** stars indicate p values less than 0.0001., n.s. = not significant. …”

Table_1_Effectiveness of written emotional disclosure interventions for eating disorders: a systematic review and meta-analysis.DOCX by Yufei Wang (171069)

“…The written emotional disclosure intervention can decrease eating disorder symptoms scores (SMD = −0.20, 95% CI [−0.34, −0.05], Z = 2.59, p = 0.01), body dissatisfaction scores (SMD = 0.37, 95% CI [0.21, 0.52], Z = 4.59, p < 0.001), and thin ideal internalization score (SMD = 0.42, 95% CI [0.22, 0.62], Z = 4.12, p < 0.001). …”

Table_1_Outcomes of retroperitoneal fibrosis-related hydronephrosis and its risk factors for poor prognosis: a multi-center retrospective cohort study in Chinese patients.DOCX by figshare admin frontiersin (4545187)

“…After 60.43 ± 34.53 months of follow-up, 36 patients had poor prognosis, which was associated with severe kidney impairment, bilateral hydronephrosis and inflammation status (elevated ESR and IgG) at diagnosis by case–control study. eGFR and creatinine were independent risk factors after adjusting for all other significant associations (p = 0.002 and p = 0.067, respectively). …”

Table2_Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.DOC by Liyuan Yu (5341841)

“…GXST and WM combination was significantly more effective than WM alone across several metrics: clinical efficacy rate (odds ratio [OR] = 4.05, 95% confidence interval [CI] = 3.42–4.80), electrocardiogram improvement (OR = 3.39, 95% CI = 2.35–4.87), enhancement in left ventricular ejection fraction (mean difference [MD] = 1.07, 95% CI = 0.69–1.46), reduction in total cholesterol levels (MD = −0.78, 95% CI = −1.20 to −0.35), decrease in tumor necrosis factor-alpha (MD = −1.36, 95% CI = −2.18 to −0.53), and improvement in Chinese medicine evidence score (OR = 3.77, 95% CI = 2.20–6.43). …”

Image 3_The global burden of neonatal sepsis attributable to air pollution from 1990 to 2021: findings from the global burden of disease study 2021.jpeg by Jiajia Duan (9351878)

“…</p>Conclusion<p>Overall, air pollution remains a significant public health challenge threatening neonatal health. …”

Table 3_Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster.xlsx by Florance Parweez (22534262)

“…The intracellular levels of polyamines, especially spermidine, decrease in aging. Oral spermidine supplementation has been reported to alleviate aspects of aging-related disease in animal models, including decline in learning and memory. …”

Image 3_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. …”

Table_1_Partnership and relationship happiness in endometriosis related chronic pelvic pain: a multicenter case–control study.docx by Samia el Hadad (19844874)

“…</p>Conclusion<p>Given the significance of partnership in dealing with chronic diseases and the connection between symptoms of endometriosis and a decrease in partnership quality, it is essential to incorporate strategies that alleviate the negative impacts on relationships for both partners into medical support.…”

Image 1_A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia.tif by Stephen B. Simons (19931955)

“…</p>Results<p>Treatment with 0.75Hz significantly reduced sleep onset latency (SOL) by 53% when compared with pre-treatment baselines and was also significantly more effective than stimulation with 25Hz which reduced SOL by 30%. …”

Table 1_Multi-omics analyses reveal altered gut microbial thiamine production in obesity.xlsx by Yu Xia (8822)

“…</p>Results<p>Metabolomic analysis identified significantly lower levels of fecal thiamine in individuals with obesity (P_Wilcoxon < 0.001). …”

Data Sheet 1_Neuronal expression of S100B triggered by oligomeric Aβ peptide contributes to protection against cytoskeletal damage and synaptic loss.docx by Joana Saavedra (11327910)

“…We used the AD mouse model AβPPswe/PS1A246E to show that neuronal S100B levels are significantly higher in 10-month-old animals, and cellular assays to demonstrate that Aβ oligomers significantly increase S100B expression in SH-SY5Y cells, but not monomeric or fibrillar Aβ. …”

Data Sheet 1_A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia.docx by Stephen B. Simons (19931955)

“…</p>Results<p>Treatment with 0.75Hz significantly reduced sleep onset latency (SOL) by 53% when compared with pre-treatment baselines and was also significantly more effective than stimulation with 25Hz which reduced SOL by 30%. …”

Image 3_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

<b>Cannabinoid Receptor 2 Agonism Demonstrates Therapeutic </b><b>Potential in Experimental Models of Relevance to Diabetic Retinopathy</b> by Cayla D. Ontko (21434062)

“…<i>In vivo</i>, both intraocular and systemic HU-308 administration significantly decreased retinal leukostasis in cytokine-induced inflammation and STZ-induced diabetes. …”

DataSheet1_Exploring the effects of moxibustion on cognitive function in rats with multiple cerebral infarctions from the perspective of glial vascular unit repairing.DOCX by Jingji Wang (19925733)

“…Notably, levels of glial fibrillary acidic protein (GFAP) and complement component 3 significantly increased, but those of Connexin43 (CX43) and platelet derived growth factor receptor β (PDGFRβ) significantly decreased in the hippocampus of the rats receiving MMI. …”

Table 1_Genomic and phenotypic characterization of two novel human-derived Limosilactobacillus reuteri strains with unique probiotic traits.docx by Lijuan Yang (1538233)

“…In co-culture with LS174T cells, both strains decrease the production of Mucin-2, a key component of the gut barrier, with LLR2 showing significantly greater efficacy. …”

Image 1_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”

Data Sheet 1_Treatment of bacterial biothreat agents with a novel purified bioactive lactoferrin affects both growth and biofilm formation.docx by Christian Xander (9120108)

“…Here, we show that Lactea Lf can significantly inhibit biofilm and decrease the overall growth in a dose dependent manner for all Burkholderia species tested. …”

Image 4_Benign regulation of short-chain fatty acids: the underlying mechanism of the beneficial effects of manual acupuncture on cognitive ability and the intestinal mucosal barri... by Ning Ding (456674)

“…</p>Results<p>Compared with those in the C57BL/6 control (Cc) group, cognitive ability was significantly decreased, SCFAs and FFAR3 expression were obviously decreased, intestinal barrier integrity was drastically impaired, and the expression of NF-κB and the levels of intestinal IL-1β and TNF-α were increased in the APP/PS1 control (Ac) group. …”