يعرض 2,221 - 2,240 نتائج من 6,685 نتيجة بحث عن '(( significantly ((largest decrease) OR (linear decrease)) ) OR ( significantly improve decrease ))', وقت الاستعلام: 0.66s تنقيح النتائج
  1. 2221

    Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

    منشور في 2025
    "…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"
  2. 2222

    Discovery of Tamsulosin Derivatives with Shifted Selectivity from the α<sub>1</sub>‑Adrenergic Receptor to ANO1 as Potent Antiosteoporotic Agents حسب Chaoquan Tian (21009122)

    منشور في 2025
    "…The potency of compound <b>10</b> against ANO1 was comparable to that of <b>Tam</b> (IC<sub>50</sub>: 4.57 vs 7.22 μM), but its selectivity over α<sub>1</sub>-AR was significantly improved. Compared with <b>Tam</b>, the potency of compound <b>10</b> against α<sub>1A</sub>-, α<sub>1B</sub>-, and α<sub>1D</sub>-AR decreased by 118-fold, 642-fold, and 10,000-fold, respectively. …"
  3. 2223

    Data Sheet 1_Pharmacist-led surgical medicines prescription optimization and prediction service improves patient outcomes - a machine learning based study.docx حسب Xianlin Li (2004964)

    منشور في 2025
    "…In Phase 3, the acceptance rate of pharmacist recommendations rose to 71.3%, while the length of stay, total hospitalization costs, and medication costs significantly decreased (p < 0.05), indicating overall improvement compared to Phase 1.…"
  4. 2224

    DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf حسب Bo Yao (308010)

    منشور في 2024
    "…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
  5. 2225

    DataSheet2_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf حسب Bo Yao (308010)

    منشور في 2024
    "…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
  6. 2226

    DataSheet1_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf حسب Bo Yao (308010)

    منشور في 2025
    "…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
  7. 2227

    DataSheet2_Mechanism of Valeriana officinalis L. extract improving atherosclerosis by regulating PGC-1α/Sirt3/Epac1 pathway.pdf حسب Bo Yao (308010)

    منشور في 2025
    "…Furthermore, the drug significantly increased the mRNA and protein expression of PGC-1α and Sirt3 in aortic tissue, while decreasing the mRNA and protein expression of Epac1, Caspase-3, and Caspase-9.…"
  8. 2228
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  10. 2230
  11. 2231
  12. 2232
  13. 2233
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  16. 2236

    Model validation of kinetic parameters. حسب Ning Zuo (17295415)

    منشور في 2025
    الموضوعات:
  17. 2237
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  19. 2239
  20. 2240