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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Roles of the pharmacist in the use of safe and highly effective long‐acting reversible contraception
منشور في 2014"…Use of long-acting reversible contraceptive (LARC) methods has been increasing in recent years after efforts to educate providers and patients. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care
منشور في 2025"…<h3>Background</h3><p dir="ltr">Venous Thromboembolism (VTE) is a common, preventable complication in trauma. Low-molecular-weight heparin (LMWH) is recommended for VTE prophylaxis (VTEp). …"
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Otosyphilis: A rare case of reversible hearing loss in a young man with secondary syphilis
منشور في 2023"…<h3>Background</h3><p dir="ltr">Over the last decade, it has been noticed a significant increase in the number of cases of syphilis with a concurrent increased number of patients presenting with syphilis-related complications. …"
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A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
منشور في 2021"…Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). …"
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
منشور في 2013"…At the end of the experiment, analysis of the effluent brine showed a remarkable decrease of electroconductivity (EC), PO43−, chemical oxygen demand (COD) and K+ with a reduction of 60%, 74%, 70%, and 60%, respectively, as compared to the influent. …"
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Comparative life-cycle assessment of reverse osmosis and microalgae-based treatment for hypersaline oilfield produced water
منشور في 2025"…However, it also presented important trade-offs, including a 2.19-fold increase in land use, a 9.7-fold increase in marine eutrophication driven by the nitrogen content of the glucose feedstock, and higher human carcinogenic toxicity. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Strategies for the use and interpretation of functionalized reverse osmosis membranes with improved antifouling and anti-scaling properties for the desalination process
منشور في 2024"…The membrane fouling caused by the constituents of feedwater affects the performance of the reverse osmosis (RO) membrane by partially or completely blocking the membrane pores and increasing the system's operating cost. …"
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Development of a novel tailored ion-imprinted polymer for recovery of lithium and strontium from reverse osmosis concentrated brine
منشور في 2022"…It was noticed that the maximum adsorption capacity (Qm) was increased as the temperature rise from 714.3 mg/g at 25 °C to 2500 mg/g at 45 °C. …"