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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
less decrease » teer decrease (Expand Search), we decrease (Expand Search), levels decreased (Expand Search)
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18361
Table1_Adverse event signal mining and severe adverse event influencing factor analysis of Lumateperone based on FAERS database.docx
Published 2024“…Conversely, concomitant use of CYP3A4 inhibitors or drugs metabolized by CYP3A4 was associated with a decreased risk of severe AEs (OR = 0.524 [0.434, 0.633], P = 0.000).…”
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18362
Table11_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx
Published 2024“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
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18363
Data Sheet 1_Cross-species analysis of FcγRIIa/b (CD32a/b) polymorphisms at position 131: structural and functional insights into the mechanism of IgG- mediated phagocytosis in hum...
Published 2025“…In contrast, allele-specific effects in macaques were highly significant; the macaque P<sup>131</sup> variant showing uniformly reduced IgG affinity. …”
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18364
Network structure of OSA.
Published 2025“…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
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18365
DataSheet1_Erlotinib regulates short-term memory, tau/Aβ pathology, and astrogliosis in mouse models of AD.doc
Published 2024“…Moreover, erlotinib treatment decreased astrogliosis in 6-month-old PS19 mice and reduced proinflammatory responses in primary astrocytes (PACs) from PS19 mice. …”
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18366
Table 5_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18367
Data Sheet 1_Metformin upregulates circadian gene PER2 to inhibit growth and enhance the sensitivity of glioblastoma cell lines to radiotherapy via SIRT2/G6PD pathway.docx
Published 2025“…Meanwhile, NADPH+ production and G6PDH enzyme activity significantly decreased. Further study validated that metformin inhibited the cell growth of GBM cell lines through up-regulating PER2 and inhibited SIRT2/G6PD signaling pathway, enhancing radiotherapy(RT) sensitivity. …”
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18368
Table8_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx
Published 2024“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
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18369
The performance of S-YOFEO model on MOT17.
Published 2025“…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
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18370
Table 3_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18371
Table5_Unveiling the molecular landscape of PCOS: identifying hub genes and causal relationships through bioinformatics and Mendelian randomization.xlsx
Published 2024“…</p>Conclusions<p>Our bioinformatics combined with MR analysis revealed that CD93, CYBB, DOCK8, IRF1, MBOAT1, MYO1F, NLRP1, NOD2, PIK3R1 increase the risk of PCOS, while PTER decreases the risk of PCOS. This discovery has implications for clinical decision-making in terms of disease diagnosis, prognosis, treatment strategies, and opens up novel avenues for drug development.…”
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18372
Five multi-target tracking evaluation indexes.
Published 2025“…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
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18373
Data Sheet 2_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf
Published 2025“…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
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18374
Genetic and structural factors contributing to the dominance and persistence of goose astrovirus type 2
Published 2025“…<p>Goose astrovirus (GoAstV) has emerged as a significant pathogen affecting the goose industry in China, with GoAstV-2 becoming the dominant genotype since 2017. …”
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18375
Table 7_Association of MIF rs1007888 and ARAP1 rs1552224 genetic variants with the risk of gestational diabetes mellitus in a chinese population; case study and meta-analysis.xlsx
Published 2025“…ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. …”
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18376
Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff
Published 2025“…Gene ontology analysis revealed a significant upregulation of pathways involved in inflammatory processes, response to ER stress, and the ER-associated degradation pathway. …”
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18377
Algorithm flowchart of OFEO.
Published 2025“…OSA is highly sensitive to information of different scales, and its one-time aggregation property substantially decreases the computational overhead of the model. …”
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18378
Data Sheet 1_Cellular effects of splenectomy on liver regeneration after 70% resection.pdf
Published 2025“…Splenectomy also correlated with decreased rates of Ly6C+ monocyte and Ly6G+ leukocyte migration. …”
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18379
Data Sheet 1_The impact of immune checkpoint inhibitors on prognosis in unresectable hepatocellular carcinoma treated with TACE and lenvatinib: a meta-analysis.zip
Published 2025“…The TACE+L+I group had a significantly higher incidence of hypothyroidism compared to the TACE+L group (RR = 1.81, 95%CI:1.20, 2.71, p<0.05), but there was no significant difference in other adverse events, such as hypertension, diarrhea, hand-foot syndrome, fatigue, elevated AST, elevated ALT, decreased appetite, hypothyroidism, abdominal pain, thrombocytopenia, rash, and nausea.…”
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18380
Data Sheet 1_Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence.docx
Published 2025“…The CE-to-cholesterol ratio of 0.44 in the recurrent tumor suggests significant cholesterol esterification during malignant progression.…”