Image 1_HIF1A acts as target of XiHuang Pill in the treatment of papillary thyroid cancer by regulating dedifferentiation.tif by Xu-Zhe Yu (21509801)

“…Further, only HIF1A was upregulated in the advanced stage of PTC and significantly correlated with the dedifferentiation (all P < 0.05). …”

Table_3_Bacillus velezensis B105-8, a potential and efficient biocontrol agent in control of maize stalk rot caused by Fusarium graminearum.DOCX by Shuang Wang (46453)

“…S-NP activity showed an initial increase with a peak of 20,337 nmol/h/g, followed by a decrease, but activity remained significantly better than control treatment with chemical fungicides. …”

Data_Sheet_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.PDF by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Image 9_Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice.tif by Yu-Syuan You (21288113)

“…Consequently, mice treated with CCT007093 exhibited significantly reduced serum HBsAg levels compared to vehicle-treated mice. …”

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…Fecal zonulin and plasma HIF-2α were significantly elevated in both NA and D2T groups, whereas fecal D-lactate showed a pronounced decrease in the NA and D2T groups. …”

Image 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.pdf by Zhanyi Yang (5142182)

“…In hepatocytes, MORC4 knockdown significantly elevated total TC/TG levels, as well as enhanced lipid accumulation. …”

Table_1_Causal relationship between non-alcoholic fatty liver disease and sarcopenia: a bidirectional Mendelian randomization study.DOCX by Meng Chen (48769)

“…Published summary statistics were used to obtain instrumental variables (IVs) at the genome-wide significance level.</p>Results<p>IVW analysis showed that the risk of NAFLD was reduced when walking pace was increased (OR = 0.435, 95%CI 0.240–0.789, p = 0.006); Increasing appendicular lean mass (ALM) decreased the risk of NAFLD (OR = 0.906, 95%CI 0.838–0.980, p = 0.014); Those older than 60 were more likely to suffer from NAFLD if they had low grip strength (OR = 1.411, 95%CI 1.087–1.830, p = 0.0012). …”

Table 2_Global, regional and national burdens of otitis media in children and adolescents from 1990 to 2021 and its predictions to 2040.docx by Ru Chen (186859)

“…Regionally, both mortality rates and DALYs significantly decrease with increasing SDI. Sub-Saharan Africa and South Asia have high levels of incidence and prevalence. …”

Image1_DNA methylation-mediated FGFR1 silencing enhances NF-κB signaling: implications for asthma pathogenesis.TIF by Minglu Meng (19725085)

“…Overexpression of FGFR1 in BEAS-2B cells significantly enhanced cell proliferation and stimulated NF-ĸB transcriptional activity in HERK-293T cells. …”

Table 2_Dietary retinoic acid improved the growth, lipid metabolism and immune status in Macrobrachium rosenbergii.docx by Qin-Cheng Huang (20944886)

“…Compared to the prawns fed 4 mg/kg dietary RA, there was significantly lower lipid deposition in the muscle, hepatopancreas and whole body of prawns fed 296 mg/kg dietary RA. …”

Table 1_Morc4 is a novel functional gene associated with lipid metabolism in BXD recombinant inbred population.xlsx by Zhanyi Yang (5142182)

“…In hepatocytes, MORC4 knockdown significantly elevated total TC/TG levels, as well as enhanced lipid accumulation. …”

Data Sheet 1_Altered immune cell profiles in blood of mature/peripheral T-cell leukemia/lymphoma patients: an EuroFlow study.docx by F. Javier Morán-Plata (18986483)

“…In contrast, SS/MF showed neutrophilia, associated with decreased numbers of dendritic cells and NK-cells, potentially reflecting their increased migration from blood to the skin. …”

Table 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

“…LAMP1 expression remained unchanged during autophagy modulation but decreased with LC3C knockdown and vice versa. Notably, VHL(+) cells expressed less LAMP1 than VHL(-) cells.…”

Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

“…LAMP1 expression remained unchanged during autophagy modulation but decreased with LC3C knockdown and vice versa. Notably, VHL(+) cells expressed less LAMP1 than VHL(-) cells.…”

Data Sheet 1_STING regulates NETs formation by activating GSDMD in influenza viral pneumonia.pdf by Rongrong Huang (819212)

“…Symptoms of pneumonia in STING-KO mice infected with PR8 were significantly milder than those in WT mice, and NETs were less likely to form in the lung tissue of STING-KO mice. …”

Table 1_The global burden of childhood diarrhea and its epidemiological characteristics from 1990 to 2021.doc by Hai-Yan Zhu (17595684)

“…The ASPR is mostly concentrated in children aged 10–14 years old, among which the ASPR of children under 5 years old has the most significant decline, from 3,138.81 per 100,000 people (95% UI: 2,749.19–3,557.51) in 1,990–885.07 per 100,000 people (95% UI: 755.93–1,029.39), a decrease of 71%. …”

Supplementary Material for: Conversion Ability of Immunotherapy in Hepatocellular Carcinoma: Insights from the International Converse Study by figshare admin karger (2628495)

“…The primary endpoint was the curative conversion rate, differentiating potential conversion (PC) - when objective response (OR) resulted in a consistent decrease in tumour burden and alpha-fetoprotein levels - from actual conversion (AC), when OR led to curative treatment. …”

Table 2_A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical stud... by Xiao-Min Lv (21575681)

“…</p>Results<p>Our meta-analysis comprises 26 studies and 365 animals demonstrates the following effects of resveratrol compared to the control group: a significant increase in the number of retinal ganglion cells (SMD = 3.91, 95% Cl = [2.97, 4.86], p < 0.00001) and superoxide dismutase activity (SMD = 3.14, 95% Cl = [0.96, 5.33], p = 0.005). …”

Thermogenetic activation in male flies. by Joseph D. Jones (13883524)

“…Two-way repeated measures ANOVA followed by Sidak’s multiple comparisons revealed that control and most FBS lines show a significant decrease in nighttime sleep bout duration between 22 °C and 31 °C, and 4 sleep-promoting FBS lines show no difference between 22 and 31 °C (FBS42, FBS53, FBS81, and FBS84) while FBS45 and FBS68 show an increase in nighttime sleep bout duration at 31 °C. …”

Table 1_A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical stud... by Xiao-Min Lv (21575681)

“…</p>Results<p>Our meta-analysis comprises 26 studies and 365 animals demonstrates the following effects of resveratrol compared to the control group: a significant increase in the number of retinal ganglion cells (SMD = 3.91, 95% Cl = [2.97, 4.86], p < 0.00001) and superoxide dismutase activity (SMD = 3.14, 95% Cl = [0.96, 5.33], p = 0.005). …”