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teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increase » increased (Expand Search)
less decrease » mean decrease (Expand Search), we decrease (Expand Search), levels decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
increase » increased (Expand Search)
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Image_1_Depletion of Host Cell Focal Adhesion Kinase Increases the Susceptibility to Invasion by Trypanosoma cruzi Metacyclic Forms.TIF
Published 2019“…On the other hand, when treated with FAK-specific inhibitor PF573228, WT cells exhibited a dense meshwork of actin filaments, lysosome accumulation around the nucleus, and had increased resistance to MT invasion. In cells treated with PF573228, the phosphorylation levels of FAK were reduced and, as a consequence of FAK inactivation, diminished phosphorylation of extracellular signal-regulated protein kinases (ERK1/2) was observed. …”
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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Reducing <i>htt</i> expression increases <i>Abl</i>-FRET biosensor phosphorylation state during MB development.
Published 2021“…FRET efficiency is significantly increased in <i>htt</i><sup><i>int</i></sup>/+ flies for all confocal planes along the anterior-posterior axis except for the three located 3 to 4 μm from the initial confocal plane. …”
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The Discovery of Exarafenib (KIN-2787): Overcoming the Challenges of Pan-RAF Kinase Inhibition
Published 2024Subjects: -
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