Supplementary Material for: Promising Therapeutic Targets for Intracranial Aneurysms: A Systematic druggable genome-wide Mendelian Randomization by figshare admin karger (2628495)

“…Methods:We systematically identified genetic variants associated with 1577 druggable genes utilizing gene expression, DNA methylation, and protein expression quantitative trait loci. …”

Table 1_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.xlsx by Lucas T. Woods (11163549)

“…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …”

Table 2_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.xlsx by Lucas T. Woods (11163549)

“…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …”

Data Sheet 1_Salivary gland transcriptomic analysis and immunophenotyping in the IL-14α transgenic mouse model of Sjögren's disease.docx by Lucas T. Woods (11163549)

“…Results demonstrated significantly increased sialadenitis in IL-14αTG compared to C57BL/6 mice that correlated with an increased proportion of marginal zone B cells infiltrating the submandibular gland. …”

Data Sheet 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

The efficacy of colchicine compared to placebo for preventing ischemic stroke among individuals with established atherosclerotic cardiovascular diseases: a systematic review and me... by Shulai Zhu (20443603)

“…We identified 13 eligible clinical trials with 24900 participants. Colchicine significantly decreased the risk of ischemic stroke (relative risk (RR) 0.85, 95% confidence interval (CI) (0.72, 0.99), I²=2.92%) among those with established atherosclerotic cardiovascular diseases. …”

Acid attack test of HPC at 28, 56, and 90 days. by Fadi Althoey (13040091)

“…Durability was enhanced with a 14–17% reduction in water absorption and sorptivity and a 25.2% decrease in chloride penetration. Acid resistance improved by 26%. …”

Table 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Data Sheet 2_Unveiling the mechanisms of American ginseng and achyranthes in treatment of primary Sjogren’s syndrome via mtDNA-cGAS-STING pathway insights from network pharmacology... by Haotian Li (640676)

“…Animal experiments demonstrated that baicalin can significantly reduce inflammatory cytokines of IL-18, TNF-α, IFN-α, and IFN-β,CXCL-10 (p < 0.05), decrease mtDNA release, and downregulate cGAS-STING pathway-related proteins including cGAS, STING, CASP3, ZBP1, TBK1, p-STING, p-TBK1, IRF3, p-IRF3 and BAX.…”

Image 3_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Supplementary file 1_Greening the start-up of reactive distillation: A combined experimental and LCA study from cold and empty state.pdf by Nikhil Sharma (571073)

“…The optimal start-up demonstrates a 64% reductions in start-up time compared to traditional start-up, which significantly reduces environmental impacts. Key improvements in emissions included a 68% decrease in GWP, 56% reduction in fossil depletion, and 69% reduction in human toxicity when compared with the traditional method. …”

Overview design of F-TransR model architecture. by Guibing You (21728593)

“…On the Reddit dataset, MSE and MAPE decrease by 6.6% and 5.3%, respectively, and improves to 0.854. …”

R project including metadata update. by Frederik Stein (22146203)

“…Without such amendments, the accumulation of contradictory species assignments within BINs will continue to rise and the reliability of specimen identification by BOLD will decrease.</p></div>…”

Table 2_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx by Ziqi Han (12840074)

“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”

Table 3_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.xlsx by Chen Chen (6544)

“…Transcriptomic analysis revealed that AT-1 significantly modulated the expression of S100A8 and S100A9. …”

Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Transcriptomic analysis revealed that AT-1 significantly modulated the expression of S100A8 and S100A9. …”

Table 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.docx by Giulia Santarelli (14246638)

“…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Table 1_Emergency department utilization among youth in foster care: benefits of a patient-centered medical home.pdf by Nicholas Szoko (11260475)

“…Findings suggest that PCMHs may decrease healthcare costs and better support foster youths’ specific health needs.…”

Table 1_Experimental-numerical investigation on the performance of basalt fiber reinforced asphalt mixture.xlsx by Zizhou Xue (22434397)

“…The results indicated that as the fiber content increased, the bulk density and voids filled with asphalt with 6 mm and 9 mm fiber content first decreased, then increased, and finally decreased again. …”