Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Table 7_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 1_A systematic review of the effects of nanoplastics on fish.pdf by Asok K. Dasmahapatra (2275549)

“…NAP exposure leads to significant adverse effects including increased oxidative stress, decreased locomotor and foraging activities, altered growth, immunity, lipid metabolism, and induced neurotoxicity. …”

Image 8_EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach.png by Eyad Talal Attar (22124251)

“…</p>Result<p>Examination of eventrelated potentials (ERPs) demonstrated that P300 amplitude showed significant growth when responding to oddball stimuli, which indicates increased attention allocation (p < 0.05). …”

Table 3_Comparative performance evaluation of large language models in answering esophageal cancer-related questions: a multi-model assessment study.xlsx by Zijie He (8194938)

“…Retesting showed improvements in overall quality, yet some responses showed decreased completeness and relevance.</p>Conclusion<p>Large language models have considerable potential in answering questions about esophageal cancer, with significant differences in completeness. …”

Table 9_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”

Table 10_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”

Table 5_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf by Yingchao Wu (2870927)

“…Furthermore, SSA displayed inhibitory effects on tumor growth with minimal toxicity in animal studies, accompanied by activated biomarkers of cellular senescence and decreased expression of p-Akt and p-PI3K.</p>Conclusion<p>Taken together, based on the preliminary results of network analysis and further experimental validation, this study revealed that SSA significantly induced cell cycle arrest and senescence, and the inhibition of ROS-mediated PI3K/Akt pathway may be the potential mechanism in this process.…”

Data Sheet 1_OSH45, a homeobox transcription factor, coordinates low-phosphate adaptation in rice.pdf by Hong Lu (58784)

“…<p>Phosphorus (P), an essential macronutrient critical for plant growth and development, faces significant availability constraints in agricultural soils, substantially limiting crop yield potential. …”

Data Sheet 1_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.pdf by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Figure 6 from Membrane-bound Heat Shock Protein mHsp70 Is Required for Migration and Invasion of Brain Tumors by Maxim Shevtsov (15023874)

“…<p>Inhibition of mHsp70 results in decreased motility of patient-derived brain tumor cells. …”

Image 1_Can Chinese patients restore normal knee function 1 year after total knee arthroplasty?.jpeg by YiShun Guo (22629887)

“…In the 65–75-year group, only females showed decreased performance in picking up items from the ground (p < 0.001). …”

Table1_Assessing physical fitness adaptations in collegiate male soccer players through training load parameters: a two-arm randomized study on combined small-sided games and runni... by YanXiu Quan (19645810)

“…Although there were positive trends in variables such as RSA and 30-15IFT, these changes were modest and not statistically significant. The results suggest that while the combined SSGs and HIIT approach shows potential, its impact on physical fitness over a 4-week period is limited, with some variables, like CMJ, even showing decreases.…”

Table 4_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Over the past 32 years, the average annual percentage change (AAPC) in the ASPR was statistically significant at −7.60% (t = −2.68, p < 0.05). Moreover, the annual percentage change (APC) in ASIR and ASPR showed the most significant decline from 2012 to 2015, with APCs of −70.47% (t = −3.01, p < 0.05) and − 66.55% (t = −14.94, p < 0.05), respectively.…”

Data Sheet 1_Intratumoral and fecal microbiota reveals microbial markers associated with gastric carcinogenesis.docx by Yiwen Wang (666361)

“…Network analysis showed that the positive correlation with GC-enriched bacteria increased, and the positive correlation with GC-depleted bacteria decreased compared to healthy individuals. Functional analyses indicated that pathways related to carbohydrate metabolism were significantly enriched in GC, while biosynthesis of unsaturated fatty acids was diminished. …”

Image 3_Can Chinese patients restore normal knee function 1 year after total knee arthroplasty?.jpeg by YiShun Guo (22629887)

“…In the 65–75-year group, only females showed decreased performance in picking up items from the ground (p < 0.001). …”

India-Asia collisional processes: constraints from the Eocene magmatic rocks in the southern Tibetan Plateau by Li-Qiang Zhang (1312050)

“…<p>The India-Asia collision has been one of the most significant geological events on Earth over the last 100 Ma. …”

Table 3_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx by Zemin Liu (224306)

“…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …”

Data Sheet 1_Decoding the hypoxia-exosome-immune triad in OSA: PRCP/UCHL1/BTG2-driven metabolic dysregulation revealed by interpretable machine learning.zip by Weilong Ye (12984647)

“…Immune analysis revealed significant correlations between gene expression and immune cell subsets, particularly CD56 bright natural killer cells and Memory B cells. …”