يعرض 19,221 - 19,240 نتائج من 21,342 نتيجة بحث عن '(( significantly ((level decrease) OR (greatest decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.52s تنقيح النتائج
  1. 19221

    CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells. حسب Jovana Deretic (13113617)

    منشور في 2025
    "…The mean cilia length in CCDC66-depleted cells decreased to 0.67-fold compared to the mean control length. …"
  2. 19222

    Data Sheet 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.xlsx حسب Yu Chen (29959)

    منشور في 2025
    "…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…"
  3. 19223

    Table 1_Mitochondrial damage and IL-1β production in monocytes caused by Neospora caninum infection are mediated by dense granule protein 7 and prohibitins.docx حسب Yu Chen (29959)

    منشور في 2025
    "…Using inhibitors of PHB1 or transfecting N. caninum-infected THP-1 cells with PHB1 siRNA significantly decreased IL-1β production, but not TNF-α.…"
  4. 19224

    Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer حسب Lisa N. Chesner (19677087)

    منشور في 2025
    "…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …"
  5. 19225

    Supplementary Tables 1-7 from Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer حسب Lisa N. Chesner (19677087)

    منشور في 2025
    "…<p>Table S1: List of top 20 significant (p< 0.05) genes from a whole-genome CRISPRi FACS-based screen which increased or decreased MHC Class I expression upon knockdown. …"
  6. 19226

    Inference of cell-type proportions from bulk RNAseq and dynamics during myocardial infarction in α1A-AR-KO mice. حسب Brian Gural (21781982)

    منشور في 2025
    "…<b>(D)</b> Estimation of cardiac cell type composition changes post-myocardial infarction (MI) and in α1A-AR knockout (cmAKO) mice, showing increased proportions of macrophages and fibroblasts and decreased proportions of cardiomyocytes, with more pronounced changes in cmAKO mice. …"
  7. 19227

    Data Sheet 1_Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized cont... حسب Shi-Bing Liang (10200806)

    منشور في 2025
    "…Adding TXL to WM showed a non-significant trend toward reducing myocardial infarction [RR 0.34, 95% CI (0.05, 2.12); NNT = 41] and sudden cardiac death [RR 0.34, 95% CI (0.01, 8.28); NNT = 65]. …"
  8. 19228

    Data Sheet 1_Global burden of disease among adolescents and young adults with drug use disorders, 1990–2021: based on GBD 2021.doc حسب Ming Wang (172316)

    منشور في 2025
    "…Additionally, gender plays a significant role in the distribution of this burden, with males experiencing a higher burden than females. …"
  9. 19229

    Data Sheet 2_CD44 knockdown alters miRNA expression and their target genes in colon cancer.pdf حسب Diana Maltseva (11678641)

    منشور في 2025
    "…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …"
  10. 19230

    Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip حسب Xueshan Chen (17477633)

    منشور في 2025
    "…Further transcriptome analysis demonstrated that PGL exerted significant transcriptional changes to bacteria. Enrichment analysis showed PGL could inhibit growth of P. aeruginosa and E. coli by repressing the biosynthesis of secondary metabolites.…"
  11. 19231

    Table 4_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  12. 19232

    Image 1_iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis.tif حسب Jingyu Zhao (2371618)

    منشور في 2025
    "…Background<p>Cryptococcal meningitis (CM) is a significant global health issue, particularly affecting individuals with HIV. …"
  13. 19233

    Data Sheet 1_Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021.docx حسب Qingguo Liu (9620123)

    منشور في 2025
    "…From 1990 to 2021, the absolute number of stroke-related DALYs attributable to metabolic-risks increased by 22.23%, while the ASDR decreased by 0.78% annually. Regional disparities were evident, with East Asia reporting the largest number of stroke-DALYs attributable to metabolic-risks and Southeast Asia exhibiting the highest ASDR. …"
  14. 19234

    Focus group guide. حسب Judite Blanc (22559981)

    منشور في 2025
    "…<div><p>Amid the dismantling of state structures in Haiti, the first Black republic faces significant health disparities compared to its former colonial power, France. …"
  15. 19235

    Table 6_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx حسب Wenjun Wang (314231)

    منشور في 2025
    "…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…"
  16. 19236

    Evaluation results. حسب Briya Tariq (19666901)

    منشور في 2024
    "…It focuses on identifying and quantifying clinically significant materials in the presence of metal objects. …"
  17. 19237

    Data Sheet 1_In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms.docx حسب Alkhair Adam Khalil Mohamed (21529289)

    منشور في 2025
    "…While acetylation decreased binding affinity; it enhanced cellular activity as reported in in vitro studies indicative of the need to balance lipophilicity and binding strength in future ligand design.…"
  18. 19238

    Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

    منشور في 2025
    "…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"
  19. 19239

    Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf حسب Yu Xu (52257)

    منشور في 2025
    "…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. …"
  20. 19240

    Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag... حسب H. Bauhaus (22335913)

    منشور في 2025
    "…No statistically significant correlations were identified between lac-phe and lactate, glucose as well as anthropometric and respiratory parameters.…"