Image_2_High-fat diet mouse model receiving L-glucose supplementations propagates liver injury.JPEG by Johnny Amer (495285)

“…Lipid profile (Steatosis, ADRP and MDA) significantly increased in HFD-fed mice, both Glu supplementations (mainly the L-Glu) increased serum MDA while decreased ADRP. …”

Table 1_Correlation between CBC-derived inflammatory indicators and all-cause mortality with rheumatoid arthritis: a population-based study.docx by Yu Liu (6938)

“…Compared with the lowest tertile, the highest tertiles of SIRI (HR 1.87, 95% CI: 1.12–3.13), NLR (HR 1.79, 95% CI: 1.10–2.92), and MLR (HR 1.88, 95% CI: 1.17–3.02) were associated with an increased risk of all-cause mortality. The Kaplan-Meier analysis indicated a significant decrease in the survival probability among individuals with elevated SIRI, NLR, and MLR levels. …”

Table 1_Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study.xlsx by Can Qian (10906868)

“…Through targeted management, some antibiotics showed trends of increased or decreased usage. The detection rates of Methicillin-Resistant Staphylococcus aureus and Extended-spectrum β-lactamase-producing Escherichia coli did not show a significant decrease.…”

Table 1_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.docx by Ming Qian (429232)

“…Our results revealed significant increases in salivary oxytocin levels following NaiKan Therapy, suggesting a potential role of this practice in enhancing social bonding and emotional regulation. …”

Table 2_Investigating the psychophysiological effects of NaiKan Therapy: salivary oxytocin and cortisol release.xlsx by Ming Qian (429232)

“…Our results revealed significant increases in salivary oxytocin levels following NaiKan Therapy, suggesting a potential role of this practice in enhancing social bonding and emotional regulation. …”

Table 1_Single-cell and transcriptomic analyses reveal the role of PCDH17 in the non-inflammatory tumor microenvironment of pancreatic cancer.docx by Yong Sun (406434)

“…The low-expression group of PCDH17 showed reduced levels of inflammatory genes. Immunoinfiltration analysis indicated a significant association between T-cell infiltration and the expression of PCDH17. …”

Data Sheet 2_Single-cell and transcriptomic analyses reveal the role of PCDH17 in the non-inflammatory tumor microenvironment of pancreatic cancer.pdf by Yong Sun (406434)

“…The low-expression group of PCDH17 showed reduced levels of inflammatory genes. Immunoinfiltration analysis indicated a significant association between T-cell infiltration and the expression of PCDH17. …”

Data Sheet 1_Single-cell and transcriptomic analyses reveal the role of PCDH17 in the non-inflammatory tumor microenvironment of pancreatic cancer.zip by Yong Sun (406434)

“…The low-expression group of PCDH17 showed reduced levels of inflammatory genes. Immunoinfiltration analysis indicated a significant association between T-cell infiltration and the expression of PCDH17. …”

Data Sheet 1_Rice glycosyltransferase OsDUGT1 is involved in heat stress tolerance by glycosylating flavonoids and regulating flavonoid metabolism.doc by Guang-rui Dong (11871026)

“…Correspondingly, the loss of OsDUGT1 function caused a significant decrease in endogenous flavonoid accumulation in rice, which was demonstrated by our metabolomics analysis. …”

Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization by Xiaomin Wu (20328165)

“…The treatment also resulted in a decrease in CD68-positive microglia and reduced expression levels of iNOS and TNF-α, while increasing CD206-positive cells and the expression of Arg-1 and IL-10. …”

Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf by Gufeng Gao (16835753)

“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). …”

Sex hormone stimulation of CRISPR-modified HepG2 cells alters alpha-1 antitrypsin production by Emma Leacy (11872358)

“…IL-6 stimulation significantly increased intracellular AAT, and this effect was stronger in cells grown in DHT (Figure 1B). …”

Supplementary Material for: Which Mechanism Kicks in When? Temporal Changes in the Effect of Transtheoretical Factors on Symptom Distress Over the Course of Therapy by figshare admin karger (2628495)

“…The effects of IE, CE, and RE remained negative and significant, but the effect of AE crossed zero and became significantly positive with an increasing window number. …”

Data Sheet 1_Analysis between Helicobacter pylori infection and hepatobiliary diseases.docx by Zhenjun Yu (8205228)

“…Compared to the non-infection group, patients in the infection group exhibited a significant decrease in albumin levels and a notable increase in total cholesterol and erythrocyte sedimentation rate levels. …”

Data Sheet 3_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Data Sheet 1_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Data Sheet 2_IFNβ drives ferroptosis through elevating TRIM22 and promotes the cytotoxicity of RSL3.pdf by Huiyue Dong (4808436)

“…</p>Results<p>Here, we found that IFNβ could promote intracellular Fe²⁺ and lipid peroxidation levels, and decrease GSH levels in tumor cells. RNA sequencing data revealed that IFNβ induced a transcriptomic disturbance in ferroptosis-related genes. …”

Data Sheet 1_New evidence for T-cadherin in COVID-19 pathogenesis, endothelial dysfunction, and lung fibrosis.docx by Ekaterina Semina (12152564)

“…First, we revealed a significant decrease in T-cadherin expression in post-mortem lung samples from COVID-19 patients. …”

Table 5_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…PA treatment reduced colonic inflammation by significantly downregulating pro-inflammatory mediators (NF-κB-p65, TLR4, MyD88, TNF-α, IL-17A, IFN-γ, MPO, iNOS) and upregulating the anti-inflammatory cytokine IL-10, while IL-4 levels were also modulated. …”

Table 2_Active ingredients isolated from Periplaneta americana L. inhibit the inflammation of the colonic mucosa and regulate the gut microbiota in DSS-induced ulcerative colitis i... by Yanhuan Wang (12037016)

“…PA treatment reduced colonic inflammation by significantly downregulating pro-inflammatory mediators (NF-κB-p65, TLR4, MyD88, TNF-α, IL-17A, IFN-γ, MPO, iNOS) and upregulating the anti-inflammatory cytokine IL-10, while IL-4 levels were also modulated. …”