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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
level decrease » levels decreased (Expand Search), level increased (Expand Search), teer decrease (Expand Search)
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20741
Image 1_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif
Published 2025“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”
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20742
Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf
Published 2025“…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…”
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20743
Annual system costs and benefits.
Published 2025“…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …”
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20744
Image 2_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i...
Published 2024“…</p>Results<p>Results indicated that dietary RES and (or) HMB supplementation significantly improved the phenotype (mucosal thickness and villus width), SCFAs concentrations, and digestive enzymes (lipase, cellulase, and α-amylase) (p < 0.05). …”
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20745
Uncropped western blot images.
Published 2025“…Functional assays demonstrated that targeted repression of Pparα-En4 region significantly decreased <i><i>Ppar</i>α</i> expression and impaired brown adipocyte differentiation and thermogenesis. …”
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20746
Different types of participants have different responses to exposure to new normative environments: Judgment changes.
Published 2025“…The patterns and magnitude of parameter changes are similar for the different clusters within each normative environment, although some parameter changes are below significance.</p> <p>(TIF)</p>…”
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20747
Real-time PCR primer sequences.
Published 2025“…Compared to mice on the P-MAL diet alone, Lp<sup>WJL</sup> supplementation significantly increased muscle mass and size, resulting in enhanced muscle strength and endurance capacity. …”
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20748
<b><i>Escherichia coli α-hemolysin induces red blood cell retention in a microfluidic spleen-like device</i></b>
Published 2025“…</p><p dir="ltr">Our results suggest that the increase in cytosolic Ca<sup>2+</sup> elicited by HlyA impacts RBCs’ circulation by decreasing RBCs’ deformability and increasing spleen retention. …”
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20749
Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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20750
<b>The Mediating Role of Mental Fatigue Awareness in the Relationship Between Perceived Stress and Psychological Well-Being Among Combat Athletes</b>
Published 2025“…</b>Perceived stress significantly increased mental fatigue awareness (b = 0.732 ± 0.064, β = 0.549, p = 0.001) and directly decreased psychological well-being (b = –0.488 ± 0.166, β = –0.191, p = 0.004). …”
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20751
Description of the studied population (N = 710).
Published 2025“…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …”
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20752
Descriptive statistics for the whole sample.
Published 2025“…</p><p>Results</p><p>Logistic regression analysis revealed a strong negative association where household income increases and indoor air pollution-related mortality significantly decreases. Specifically, Households in the highest income quartile showed a 22% reduction progressively in the odds of mortality risk compared to the lowest income quintile. …”
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20753
Preventive measures during COVID-19 pandemic.
Published 2025“…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …”
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20754
Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer....
Published 2025“…In colorectal cancer cell lines, decreased PI3K phosphorylation was at least partially attributable to mevalonate depletion, a known consequence of statin treatment.…”
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20755
Image_2_Loss of Cdc42 causes abnormal optic cup morphogenesis and microphthalmia in mouse.jpg
Published 2024“…EdU incorporation is significantly downregulated. In addition, mitotic retinal progenitor cells mislocalize deeper, basal regions, likely contributing to decreased proliferation. …”
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20756
Image 2_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif
Published 2025“…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …”
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20757
Table 4_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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20758
Table 1_Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort.xlsx
Published 2025“…Hypertension was also associated with decreased OS (HR = 2.06, 95% CI: 1.11–3.81, P = 0.022).…”
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20759
Supplementary Material for: Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review
Published 2025“…Nevertheless, mortality rates decreased significantly in the latter half of the twentieth century due to effective perioperative blood pressure (BP) management. …”
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20760
Supplementary file 1_Model-based multi-year P flow analyses and strategies for sustainable food chain management in Changzhou city at China's Taihu Basin.docx
Published 2025“…Besides, urine diversion and waste incineration scenarios significantly decreased P accumulation in the food chain. …”