Data Sheet 2_Yerba Maté and its impact on glycemic control and metabolic health: a systematic review and meta-analysis.docx by Daiping Li (5007932)

“…The results with pre-diabetes patients suggest significant decreases in postprandial glucose (MD -12.76, 95% CI -16.78, -8.74; N = 2), HbA1c (MD -0.37, 95% CI -0.56, -0.18; N = 2), and the homeostatic model assessment index (HOMA index) (MD -0.24, 95% CI -0.37, -0.11; N = 2), though further research is needed to confirm these findings. …”

Data Sheet 1_Long-term effects of SGLT2 inhibitors on arrhythmias: a systematic review and meta-analysis.pdf by Peipei Li (552532)

“…The results of meta-analysis revealed that patients treated with SGLT2 inhibitors had a reduced risk of AF/AFL compared with placebo (RR 0.86; 95%CI, 0.77–0.95; I² = 0%; P = 0.003). There was no significant difference in the risk of AF/AFL between the high-dose SGLT2 inhibitors group and the low-dose SGLT2 inhibitors group (RR 0.78; 95%CI, 0.60–1.02; I² = 0%; P = 0.07), although a decreasing trend in the high-dose group was noted. …”

Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx by Ahmed Alsafar (21716735)

“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”

Propagation prediction of asymmetrically originated fractures by use of displacement discontinuity method by Qingquan Li (747754)

“…As the fluid power law index decreases, the fluid viscosity is significantly reduced due to the effect of shear thinning, causing the asymmetrically originated fractures to propagate parallel to the direction of maximum principal stress. …”

Table 5_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx by Ömer Bektaş (13827139)

“…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …”

Table 1_Spatio-temporal patterns and determinants of persistent catastrophic health expenditure in China: evidence from the China Family Panel Studies.docx by Man-ci Zhou (22776350)

“…Background<p>The escalating out-of-pocket medical expenses pose a significant threat to the financial stability of households worldwide. …”

Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I² = 99%, p < 0.001) was observed across studies.…”

Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx by Zhenzhen Wang (250368)

“…The overall TB resistance rates were significantly higher in the main urban areas. During the study period, the proportion of mono-resistance tuberculosis (MR-TB), multidrug-resistant tuberculosis (MDR-TB) and polydrug-resistant tuberculosis (PDR-TB) decreased by 59.2% (12.9–5.3%), 40.3% (12.4–7.4%), and 68.3% (6.9–2.2%), respectively. …”

Data Sheet 1_Disproportionality analysis of adverse events associated with pacritinib: a real-world study based on FDA Adverse Event Reporting System (FAERS) database.docx by Huiling Zhang (396342)

“…Common preferred terms were identified, including diarrhea, fatigue, death, nausea, platelet count decreased, and hemoglobin decreased. Notably, 26 off­-label AEs were also identified.…”

Opportunistic analysis of clinically actionable DPYD gene variants in a germline testing cohort in India by Rajdeep Raha (22056304)

“…</p> <p>A total of 95 individuals (5.3%) carried at least one decreased or no function DPYD variant, indicating a significant prevalence of clinically actionable genotypes in this Indian cohort. …”

Data Sheet 1_Peers are as persuasive as experts in reducing willingness to pay for sugary foods.pdf by Nina Arzumanyan (22759610)

“…</p>Results<p>All audio interventions significantly decreased participants’ WTP for sugar-containing products compared to sugar-free products. …”

Data Sheet 1_Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study.docx by Jingzhe Guo (5150768)

“…Tibet (124.24%) and Xinjiang (114.72%) in western China exhibited the largest percentage change in tuberculosis (TB) incidence, while Zhejiang Province (−50.45%) and Jiangsu Province (−51.33%) in eastern China showed the largest decreases. Regions with significant percentage increases in PTB mortality rates (>100%) included four western regions, six central regions, and five eastern regions. …”

Data Sheet 2_Tuberculosis disease burden in China: a spatio-temporal clustering and prediction study.docx by Jingzhe Guo (5150768)

“…Tibet (124.24%) and Xinjiang (114.72%) in western China exhibited the largest percentage change in tuberculosis (TB) incidence, while Zhejiang Province (−50.45%) and Jiangsu Province (−51.33%) in eastern China showed the largest decreases. Regions with significant percentage increases in PTB mortality rates (>100%) included four western regions, six central regions, and five eastern regions. …”

PPFIA4 Knockdown Suppresses Expression, Proliferation, and Migration in Colorectal Cancer Cells. by Wenliang Yuan (7842908)

“…<p>(A) qPCR analysis showing a significant reduction in PPFIA4 mRNA expression in the si-PPFIA4 group.…”

Table1_CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder.DOCX by Cataldo Martucci (3117069)

“…In a murine house dust mite (HDM) model of asthma exacerbated by influenza virus A (IAV) (H3N3), CHF6297 (0.1 mg/kg, i.n.) significantly decreased airway neutrophilia compared to vehicle-treated IAV/HDM-challenged mice. …”

Image1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Table1_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.docx by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Image1_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental vali... by Wenyuan Chen (1770583)

“…In vivo, EHMF alleviated back skin lesions in UV-exposed mice, reducing epidermal and dermal thickening and pathological inflammatory cell infiltration. It also decreased abnormal MMP-9 expression and collagen fiber proliferation, along with levels of inflammatory factors like TNF-α, IL-6, IL-17, and EGFR. …”

Image3_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Image4_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…</p>Results<p>Treatment of NOD/LtJ mice with MYDGF alleviated pSS, as indicated by increased salivary flow rate, reduced lymphocyte infiltration, attenuated glandular inflammation, and enhanced AQP5 and NKCC1 expression. The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”