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significantly largest » significantly larger (Expand Search), significantly less (Expand Search), significantly affect (Expand Search)
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8661
The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF...
Published 2025“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”
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8662
Supplementary Material for: Analysis of retinal and choroidal microvasculature in systemic sclerosis using optical coherence tomography angiography: A systematic review and meta-an...
Published 2024“…Meta-analysis findings revealed a significant decrease in vessel densities in both the superficial and deep capillary plexuses (SCP and DCP) among SSc patients compared to controls. …”
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8663
Rescue of <i>pbp1</i>-KD phenotypes using CRISPRi trans-complementation.
Published 2025“…Yellow arrows point to a subset of PBP1-depleted cells that have decreased RADA signal, likely due to decreased peptidoglycan metabolism. …”
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8664
Data Sheet 1_Transcriptome analysis of historic olives reveals stress-specific biomarkers.docx
Published 2025“…Photosynthetic efficiency (Fv/Fm) declined under salinity and drought stress in all cultivars, with drought causing a more significant reduction. ‘Manzanillo’ showed the highest sensitivity to drought, while the other cultivars maintained moderate efficiency under stress. …”
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8665
<b>Climate warming, rather than nitrogen deposition, reduces plant diversity and increases community homogenization in a desert steppe</b>
Published 2025“…Over this period (2006–2022), warming (mean annual temperature + 1.4°C) significantly decreased species richness and functional α-diversity throughout the experiment, whereas its effects on phylogenetic α-diversity and community phylogenetic structure were significant only before 2015 and disappeared thereafter, likely due to an extreme drought that reset the community composition. …”
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8666
Table 1_Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.docx
Published 2025“…Introduction<p>Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally. …”
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8667
Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf
Published 2024“…</p>Results<p>MyP led to significant decreases in PEG scores overall. Furthermore, MyP responders exhibited increased pain-related activation in key brain regions, including the contralateral posterior insula, bilateral ventral anterior insula, ventral anterior cingulate, dorsolateral prefrontal cortex, and nucleus accumbens. …”
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8668
Ambulatory modeling of vocal hyperfunction (Parra et al., 2025)
Published 2025“…<a href="https://doi.org/10.1044/2024_JSLHR-24-00419" rel="noreferrer" target="_blank">https://doi.org/10.1044/2024_JSLHR-24-00419</a></p>…”
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8669
Table 1_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.docx
Published 2025“…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …”
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8670
Table 2_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.xlsx
Published 2025“…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …”
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8671
Image 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf
Published 2025“…Joinpoint regression analysis revealed fluctuating trends in prevalence and incidence with periods of increase and decline, and a general decrease in mortality except during brief intervals. …”
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8672
Presentation 1_Burden of falls in China, 1992–2021 and projections to 2030: a systematic analysis for the global burden of disease study 2021.pdf
Published 2025“…Joinpoint regression analysis revealed fluctuating trends in prevalence and incidence with periods of increase and decline, and a general decrease in mortality except during brief intervals. …”
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8673
An improved <i>in vitro</i> 3T3-L1 adipocyte model of inflammation and insulin resistance
Published 2024“…Importantly, insulin resistance and inflammation were still induced in the 12 h treated adipocytes: the expression of the insulin sensitive and inflammatory genes was decreased and increased, respectively. In 72 h treated adipocytes, no significant differences were found in the viability, glucose uptake or insulin-sensitive and inflammatory gene expression. …”
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8674
Table 1_Development of the breastfed infant oral microbiome over the first two years of life in the BLOSOM Cohort.docx
Published 2025“…Introduction of solid foods was a significant milestone in oral microbiome development, triggering an increase in bacterial diversity (richness P = 0.0004; Shannon diversity P = 0.0007), a shift in the abundance of seven species, and a change in beta diversity (P = 0.001).…”
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8675
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8676
Table 1_Early identification of sarcopenia in patients with diabetes mellitus combined with osteoporosis: development and validation of a gender-specific nomogram.docx
Published 2025“…</p>Results<p>The prevalence of sarcopenia in patients with T2DM combined with osteoporosis was 33.88%, with men having a significantly higher prevalence than women. Among male patients, body mass index, 25-hydroxyvitamin D, and calcium levels were associated with a decreased risk of sarcopenia, whereas age and weight-adjusted waist index were associated with an increased risk. …”
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8677
Data Sheet 14_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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8678
Image 4_Photon budgets and the relative effects of CDOM and pigment absorptions on primary production along a coastal salinity gradient.jpeg
Published 2025“…The absorption by CDOM and detritus decreased with increasing salinity, while phytoplankton absorption followed a seasonal succession. …”
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8679
Data Sheet 1_Unravelling the impact of SARS-CoV-2 on hemostatic and complement systems: a systems immunology perspective.pdf
Published 2025“…We explored that the decreased levels of complement factor H and C1-inhibitor significantly elevate these components, whereas tissue factor pathway inhibitor and alpha-2-macroglobulin have more modest effects. …”
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8680
Table 1_Glyoxalase 1 gene expression in various types of cancer cells immunopathology: a pan-cancer analysis study.docx
Published 2025“…In summary, our study highlights GLO-1 as a significant biomarker across multiple cancers that plays a key role in cancer progression, immune modulation, and therapeutic response.…”