Data_Sheet_1_Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1G93A mice.docx by Ana Laura M. R. Tomiyama (16902930)

“…Disease progression upregulated gene transcripts for pro- and anti-inflammatory cytokines, and IFN β treatment significantly decreased mRNA expression for IL4. Overall, the present results demonstrate that a low dosage of IFN β shows therapeutic potential by increasing MHC-I expression, resulting in neuroprotection and immunomodulation.…”

Supplementary file 2_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx by Biwu Xu (21431858)

“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”

The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis by Guowen Zhao (19775328)

“…In subgroups, the interaction between higher levels of uric acid and utilizing proton pump inhibitors was significant (P for interaction = 0.034). Further research found that taking proton pump inhibitors could decrease the risk of gastrointestinal bleeding in peritoneal dialysis patients accompanied high levels of uric acid.…”

Data_Sheet_1_Dynamics of urban development patterns on thermal distributions and their implications on water spread areas of Vellore, Tamil Nadu, India.docx by D. R. Manjunath (19748899)

“…Moreover, spatial and time series analyses of WSAs indicated a significant increase in LST. Furthermore, a strong negative correlation was found between WSA and LST, with a 10% decrease in WSA potentially increasing LST by 0.12°C to 0.55°C in surrounding regions. …”

Data Sheet 1_The effect of repetitive and Deep Transcranial Magnetic Stimulation on quantitative electroencephalography in major depressive disorder.pdf by Reyhan Ilhan (20506268)

“…Patients who exhibited lower alpha activity in the left fronto-central region and higher gamma activity in the right prefrontal region following rTMS showed more significant improvements in depression symptoms. Similarly, those whose beta activity increased in the left prefrontal region but decreased in the right prefrontal region after rTMS tended to have greater reductions in depression and anxiety severity. …”

Image 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Image 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.tif by Yifan Zhou (1973332)

“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”

Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx by Li Xu (108702)

“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B₆ content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”

Image 4_Shifting landscapes: dynamic changes from pro- to anti-inflammatory leukocyte phenotype in myocardial ischemia/reperfusion injury.jpeg by Pia Kröning (21623012)

“…</p>Results<p>Expression of CD206-Geometric Mean Fluorescence Intensity (GMFI) indicative of an anti-inflammatory phenotype in neutrophils (N2) increased in PNCs at day 7. A statitstically significant decrease in the percentage of anti-inflammatory Ly6C^low PMCs was observed as early as day 3, when compared to the baseline value. …”

Image 1_Quantifying the split-elbow sign: a comprehensive study in amyotrophic lateral sclerosis.tif by Sheng-Yi He (20373678)

“…Furthermore, there was a notable decrease in SEI_MUNIX values as the disease progressed (p < 0.001). …”

Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization by Xiaomin Wu (20328165)

“…<p dir="ltr"><b>Background:</b><b> </b>Heatstroke (HS) is a critical medical condition resulting from increased body temperatures, which can lead to significant damage to the central nervous system (CNS). …”

Image 1_The impact of Internet-based healthcare derived from the COVID-19 pandemic on outpatients in a cardiology department.tif by Jie Liu (15128)

“…</p>Results<p>Compared to the period before online services (T1), the second stage (T2) saw a significant decrease in total offline and general clinic visits. …”

Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf by Chun-Wei He (3909592)

“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”

Table 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.docx by Yifan Zhou (1973332)

“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”

Table 1_Salvage chemotherapy in the intensive care unit: a case report of successful treatment of a critically ill patient with metastatic testicular germ cell tumor.docx by Karol Grela (1478173)

“…<p>Testicular cancer, predominant among young males, poses a significant healthcare challenge with varying incidence rates across European regions. …”

Table1_Identification of key biomarkers and therapeutic targets in sepsis through coagulation-related gene expression and immune pathway analysis.docx by Jing Ge (443408)

“…<p>Sepsis, characterized by a widespread and dysregulated immune response to infection leading to organ dysfunction, presents significant challenges in diagnosis and treatment. In this study, we investigated 203 coagulation-related genes in sepsis patients to explore their roles in the disease. …”

Image 4_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data Sheet 1_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.pdf by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Supplementary file 8_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx by Biwu Xu (21431858)

“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”

Additional file 1 of Genome-wide association study of agronomic traits in winter wheat (Triticum aestivum L.) using a custom SNP marker set by Mikhail Bazhenov (22354266)

“…Additional file 9.xlsx Significant marker-trait associations.…”