DataSheet1_Enhancing human islet xenotransplant survival and function in diabetic immunocompetent mice through LRH-1/NR5A2 pharmacological activation.pdf by N. Cobo-Vuilleumier (14625173)

“…Accordingly, in mice treated with BL001 for 8 weeks, the beta cell mass was preserved, while a significant decrease in alpha cells was observed compared to mice treated with BL001 for only 4 weeks. …”

Supplementary Material for: Effects of a Sugar-Sweetened Beverages Tax on Caries in Italy: a Modelling Study. by figshare admin karger (2628495)

“…The projected 2025–2034 implementation estimated to decrease the DMFT by 0.07, save €38.6 million, and €31,933 per QALY gained. …”

Data Sheet 2_Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of... by Lu-yao Cheng (20687651)

“…Between 1990 and 2021, the global ASDR decreased from 9.68 to 6.62 per 100,000, and the rate of age-standardized DALYs decreased from 330.11 to 226.28 per 100,000. …”

Addressing the Gap in Oncologist Training by Skylar Gay (20696057)

“…</p><p dir="ltr"><b>Results</b>: The algorithms successfully created radiotherapy dose distributions with decreased organs-at-risk sparing, decreased target conformality, and increased hotspots that were statistically significant (p<0.05) when assessed by dose-volume histogram metrics. …”

Table 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021.docx... by Lili Deng (152262)

“…By 2021, its mortality rates had decreased to the eighth leading cause of death.</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”

Table 3_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Table_1_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.xls by Li Liu (75607)

“…Moderate spreading is conducive to the release of the aroma of tea leaves, but fixation causes a sharp decrease in the content of most volatile metabolites. …”

Table 3_Global burden of low back pain attributable to smoking in 204 countries and territories in 1990–2021.xlsx by Baodong Wang (3359171)

“…Finally, it is forecasted that the smoking-related LBP burden will decrease from 2022 to 2036.</p>Conclusion<p>From 1990 to 2021, the global ASDR of LBP attributable to smoking decreased, and this downward trend is expected to persist. …”

Table 1_Efficacy of thymosin α1 for sepsis: a systematic review and meta-analysis of randomized controlled trials.docx by Bin Gu (223694)

“…These observations underscore the significance of personalized immunotherapy strategies in forthcoming clinical trials.…”

Figure 5 from Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection by Peter J. Mazzone (20018668)

“…Population-level modeling demonstrates significant health benefits when a blood-based test is available as an alternative for lung cancer screening.…”

Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”

Table2_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

Data Sheet 1_Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of... by Lu-yao Cheng (20687651)

“…Between 1990 and 2021, the global ASDR decreased from 9.68 to 6.62 per 100,000, and the rate of age-standardized DALYs decreased from 330.11 to 226.28 per 100,000. …”

Data Sheet 1_Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis.zip by Xinchang Lun (11996469)

“…By day 28, only SOD expression showed a significant decrease in both parasitism groups.</p>Conclusion<p>This study uncovered the dynamic changes in metabolism and immune responses of striped hamsters parasitized by Xenopsylla cheopis. …”

CPSF6-NLS chimeras confer virus-specific infectivity defects. by Nicholas Rohlfes (20577485)

“…Statistical analysis was determined using two-way ANOVA. Significant differences are indicated: * P<0.05, ** P<0.01, *** P<0.001, **** P<0.0001. …”

Supplementary file 1_Therapeutic effects of Balanites aegyptiaca DEL extract on diabetes mellitus: a systematic review.pdf by Olubukola Adebisi Odeniran (22162777)

“…All the studies were appraised for blood glucose levels, and a reduction in blood glucose was reported in all in vivo studies, regardless of the plant part used. Significant decrease in blood glucose level was recorded in Alloxan- and streptozotocin-induced rat/mice diabetes. …”

Table 1_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…The intervention had no significant effect on BM, FFM, FM, or TBW. BM, FFM (kg), TBW, and TBW/FFM were higher at SUP+FGB vs. …”

Supplementary Material for: Characteristics of asthmatic patients with IL18R1 differential expression in induced sputum by figshare admin karger (2628495)

“…IL18R1high asthma had a significant decrease in FeNO and more improvement in FEV1 during inhaled corticosteroid (ICS) treatment compared with patients having the IL18R1low subgroup. …”

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

“…Introduction<p>The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. …”

Data Sheet 1_Impact of the SARS-COV-2 pandemic on access to health services in Angola: a focus on diagnosis and treatment services for tuberculosis.docx by Susanna Caminada (16789893)

“…</p>Results<p>There was a significant decline in access to TB services during the pandemic, with a substantial decrease in reported cases (−15.5% in 2020; −18.3% in 2021) and treatment rate (from 86% in 2019 to 68% in 2020), an increase in multidrug-resistant-TB (from 0.2% in 2018 to 2.1% in 2022) and TB/HIV co-infections (from 6% in 2018 to 8.8% in 2021). …”