Cross-sectional proteomic expression in Parkinson's disease-related proteins in drug-naïve patients vs healthy controls with longitudinal clinical follow-up by Ilham Yahya Abdi (17870462)

“…The analysis identified 73 differentially expressed proteins (DEPs) of which 14 proteins were confirmed as stable potential diagnostic markers using machine learning tools. Among the DEPs identified, eight proteins—ALCAM, contactin 1, CD36, DUS3, NEGR1, Notch1, TrkB, and BTK— significantly correlated with longitudinal clinical scores including motor and non-motor symptom scores, cognitive function and depression scales, indicating potential predictive values for progression in PD among various phenotypes. …”

Impact of Stapedectomy on Tinnitus Severity and Hearing Outcomes in Patients With Otosclerosis: A Systematic Review by Noora Al Hail (23073583)

“…<h3 dir="ltr">Introduction</h3><p dir="ltr">Otosclerosis is a progressive, autosomal dominant hereditary disease of temporal bone causing tinnitus, and conductive hearing loss. …”

Income Tax-Free to Taxed: Assessing the Socioeconomic Impacts of Potential Income Tax in the UAE by Munni, Syeda Mahbuba Ayesha

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The Impact of Education on Economic Growth by ALRAEE, MAYSOON MAHMOOD

“…Substantial financial development subsequently progresses human advancement, which, thus, advances financial development. …”
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Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients by Salman M. Toor (8854751)

“…This study simultaneously provides important insights into the differential levels of CD4⁺ T cell subpopulations and IC expression in CRC TME, compared to periphery and associations with clinicopathologic features, which could be used as potential biomarkers for CRC progression and response to therapy.…”

Transhepatic Ipsilateral Right Portal Vein Embolization Extended to Segment IV by Madoff, David

“…No patient developed postembolization syndrome or progressive liver insufficiency after embolization or resection. …”
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Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis by Shilpa Kuttikrishnan (3520079)

“…<p>Abnormal expression of Forkhead box protein M1 (FOXM1) and serine/threonine kinase Budding uninhibited by benzimidazoles 1 (BUB1B) contributes to the development and progression of several cancers, including chronic myelogenous leukemia (CML). …”

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients by Ali Abouelghar (14152773)

“…Despite strong evidence supporting the role of NK cells in breast cancer (BC) control, BC still develops and progresses to form large tumors and metastases. A major mechanism of BC escape from NK immunity is the alteration of the expression of NK receptor ligands. …”

The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul, Kabir

“…IntroductionHER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. It is present in 15 to 20% of breast cancers and is clinically significant due to the availability of multiple anti-Her2 treatment options. …”
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The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul Kabir (15302407)

“…<p>Introduction HER-2/neu is a protein present on the surface of specific cancer cells and has been linked to the development and progression of certain cancer types. It is present in 15 to 20% of breast cancers and is clinically significant due to the availability of multiple anti-Her2 treatment options. …”

Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors by Salman M. Toor (8854751)

“…Importantly, immune constituents of the tumor microenvironment (TME) can influence therapy response and cancer progression. We investigated the expression of immune checkpoints (ICs) on lymphoid populations within the CRC TME and compared with cells from normal colon tissues using samples from 50 patients with varying disease stages. …”

Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function by Muge Sarper (3855454)

“…Staining of breast cancer cases for MMP-8 revealed a statistically significant loss of MMP-8 expression in DCIS with invasion versus pure DCIS (<i>p</i> = 0.001).…”

Assessment of Different Commissioning Service Methods and their Ability to Achieve the Performance KPIs in Educational Buildings in Abu Dhabi-UAE by Kuriakose, Naveen

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Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort by Nour K. Majbour (8809316)

“…<p></p><div> <h3> Background</h3> <p>Tangible efforts have been made to identify biomarkers for Parkinson's disease (PD) diagnosis and progression, with α-synuclein (α-syn) related biomarkers being at the forefront.…”

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…The main goal of this study is to identify the potential outcome of WPS on human breast cancer progression. Two breast cancer cell lines, MCF7 and BT20, were used in this investigation. …”

Buckling and crushing behavior of foam-core hybrid composite sandwich columns under quasi-static edgewise compression by Arameh Eyvazian (16500978)

“…The results revealed that using the resin pins changes the unstable Euler buckling mode to a more stable progressive end-crushing and significantly increases the buckling load, specific buckling load, and energy absorption capability, which are highly favorable. …”

Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease by El Maarri, Osman

“…Pancreatic tumors are usually diagnosed at an advanced stage in the progression of the disease, thus reducing the survival chances of the patients. …”
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Beta-Tocotrienol Exhibits More Cytotoxic Effects than Gamma-Tocotrienol on Breast Cancer Cells by Promoting Apoptosis via a P53-Independent PI3-Kinase Dependent Pathway by Idriss, Maya

“…The effect of beta-T3 on the expression level of several apoptosis-related proteins p53, cytochrome C, cleaved-PARP-1, Bax, Bcl-2, and caspase-3, in addition to key cell survival proteins p-PI3K and p-GSK-3 α/β was determined using western blot analysis. Beta-tocotrienol exhibited a significantly more potent anti-proliferative effect than gamma-tocotrienol on both cell lines regardless of their hormonal receptor status. …”
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Myeloid cells in circulation and tumor microenvironment of breast cancer patients by Salman M. Toor (8854751)

“…The aim of this study was to investigate levels and phenotypes of myeloid cells in peripheral blood (<i>n</i> = 23) and tumor microenvironment of primary breast cancer patients (<i>n</i> = 7), compared with blood from healthy donors (<i>n</i> = 21) and paired non-tumor normal breast tissues from the same patients (<i>n</i> = 7). Using multicolor flow cytometric assays, we found that breast cancer patients had significantly higher levels of tumor-infiltrating myeloid cells, which comprised of granulocytes (<i>P</i> = 0.022) and immature cells that lack the expression of markers for fully differentiated monocytes or granulocytes (<i>P</i> = 0.016). …”

The relationship between digit independence and digital sesamoids in humans and a proposal of a new digital sesamoid evolutionary hypothesis by Yammine, Kaissar

“…Simultaneously, forearm muscles showed a progressive division in hominoid evolution towards a more “individualistic” musculature yielding more mobility and independence to some fingers. …”
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