<b>Epigenetic signatures of treatment with intravenous furosemide plus hypertonic saline solution in decompensated heart failure patients: A Randomized Controlled Trial ( RCT)</b> by Antonino Tuttolomondo (3222708)

“…</p><p dir="ltr">Conclusions: Our findings revealed that in subjects with ADHF , treatment with i.v. furosemide plus HSS significantly decreased the serum levels of IL-6, sST2, hsTnT, galectin-3, and NT-proBNP and modulated some miRNA expression.…”

Continuing evolution of H5N1 highly pathogenic avian influenza viruses of clade 2.3.2.1a G2 genotype in domestic poultry of Bangladesh during 2018–2021 by Mohammed Nooruzzaman (3175290)

“…Consequently, antigenic analysis revealed a significant loss of cross-reactivity between viruses from different host species and periods. …”

Table_1_Client-based evaluation of the effects of localized vibration therapy on pain and mobility scores in dogs with radiographic bilateral hip dysplasia.docx by Kristal F. Turner (19460596)

“…</p>Results<p>There were significant decreases in average pain severity and average pain interference CBPI scores in response to 7 and 14 days of therapy compared to baseline. …”

Table 1_The impact of the herd health interventions in small ruminants in low input production systems in Ethiopia.docx by Mesfin Mekonnen Moliso (19920393)

“…Generally, the intervention impact analysis revealed that morbidity rate was significantly decreased (p = 0.009) in intervention years (6.31% in 2018 to 3.02% in 2021) and that herd health interventions provide an added value.…”

Table4_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table 1_Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis.docx by Lin Shi (65217)

“…</p>Results<p>Heart dysfunction and blood glucose showed a significant negative indirect effect on VWF through the overall leukocyte levels (indirect effect = −0.119 and −0.118, p < 0.05). …”

Image1_ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity.JPEG by Alexander Kogel (13296595)

“…Overall, ASC speck concentrations showed no significant change after CPET (7.0 ± 4.5 vs. 8.0 ± 5.4 ASC specks/µL, p = 0.3). …”

Table 1_Study on the invitro synergistic susceptibility and biofilm inhibition mechanism of ceftazidime-avibactam combined with aztreonam against carbapenem-resistant Klebsiella pn... by Guangfen Wang (20906201)

“…</p>Results<p>The comparison of synergistic indices for different enzyme-type CRKP strains with CZA and ATM combination therapy showed a statistically significant difference (p < 0.01). The time-kill assay indicated that the time-kill curves for strains carrying blaKPC-2 and blaNDM-1 resistance genes were similar between the monotherapy and combination therapy groups, while the CZA + ATM combination therapy group showed a significant decrease in bacterial concentration after 4–8 h of cultivation compared to the CZA and ATM monotherapy groups. …”

Table 1_Effects of vegetation restoration on soil fungi community structure and assembly process in a semiarid alpine mining region.docx by Yuanyuan Xue (6442661)

“…However, with prolonged restoration duration, we observed a significant decrease in α diversity accompanied by a corresponding increase in β diversity. …”

Data Sheet 1_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Image 1_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.jpeg by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Table 3_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.docx by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Table 2_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.xlsx by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Data_Sheet_1_Supplementation with inulin reverses cognitive flexibility alterations and modulates the gut microbiota in high-fat-fed mice.docx by Gabriela González-Velázquez (20131497)

“…The I group showed a decrease in bacterial diversity compared to the HF group. …”

Table 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.xlsx by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Image 2_Case Report: Is there an age cutoff beyond which PFO closure should not be offered?.jpeg by Eustaquio Maria Onorato (11277405)

“…Two-dimensional (2D) transthoracic/transesophageal echocardiography (TTE/TEE) color Doppler showed a significant right-to-left shunt (RLS) via a tunnel-type PFO associated with hypermobile floppy septum primum (HSP) and prominent Eustachian valve (EV). …”

Data Sheet 1_Global burden of disease for colorectal cancer due to diet low in whole grains from 1990 to 2021 and its projections to 2050: analysis of the global burden of disease... by Mei Yang (51996)

“…</p>Results<p>Between 1990 and 2021, the number of CRC deaths associated with a low proportion of whole grain diets worldwide increased by 82.94%, and disability adjusted life years increased by 70.3%. There is significant heterogeneity between regions: regions with high Social Population Index (SDI) have the highest decrease rate, while regions with low to medium SDI have the fastest increase rate. …”

Table 1_Influence of different scion-rootstock combinations on sugars, polyamines, antioxidants and malondialdehyde in grafted grapevines under arid conditions.docx by Sonu Krishankumar (10829367)

“…The shoots improved sugar metabolism, which led to increased resistance to drought. There was a significant increase in glucose sugar content at 75% and 50% FC, which was 85.7% to 133% at V1, 19% to 76.9% at V2, and decreased by 30% and 53% at V4.…”

Data Sheet 2_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 2_Global, regional, and national burden of acute glomerulonephritis in children and adolescents: 1990–2021 analysis and future projections.docx by Ming Liu (105953)

“…</p>Results<p>From 1990 to 2021, the global burden of AGN among children and adolescents remained significantly high. In 2021, there were approximately 170,584 new cases, representing a decrease compared to earlier years, with an age-standardized incidence rate (ASIR) of 6.47 per 100,000 (95% UI: 4.79–8.45). …”