Supplementary file 1_Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period.docx by Yingyu He (13877876)

“…On the 21st day of CS-WB storage, the oxygen carrying capacity and ATP content of RBCs showed a more significant decrease. Platelets showed characteristic ultrastructural damage and progressive decline in hemostatic function. …”

Data Sheet 1_Epidemiological trends and age-period-cohort effects on subarachnoid hemorrhage burden across the BRICS-plus from 1992 to 2021.docx by Liang Guo (95092)

“…Indonesia reported the highest age-standardized incidence rate (10.94 per 100,000 population) in 2021, while China displayed the most significant decrease, at 59.36%. The annual net drift in the SAH incidence rate ranged from −3.36%% for China to −0.50% for the Russian Federation among the eleven countries. …”

Table 1_Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study.xlsx by Can Qian (10906868)

“…Through targeted management, some antibiotics showed trends of increased or decreased usage. The detection rates of Methicillin-Resistant Staphylococcus aureus and Extended-spectrum β-lactamase-producing Escherichia coli did not show a significant decrease.…”

Table_1_Regional and social disparities in cessation behavior and motivation to quit among U.S. adult current smokers, Tobacco Use Supplement to the U.S. Census Bureau's Current Po... by Candon Johnson (11572623)

“…Notably, the Asian non-Hispanic group in the Northeast experienced a significant decrease in quit interest (–17.9%) but an increase in recent successful cessation (+369.2%).…”

Data Sheet 1_Machine learning-driven prediction model for cuproptosis-related genes in spinal cord injury: construction and experimental validation.zip by Yimin Zhou (3857113)

“…Animal experiments confirmed a significant decrease in the behavioral scores of rats in the SCI group, pathological changes in tissue sections, and differential expression of candidate genes in the SCI rat model.…”

Data Sheet 4_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Figure S5 from Immunoproteasome Activation Expands the MHC Class I Immunopeptidome, Unmasks Neoantigens, and Enhances T-cell Anti-Myeloma Activity by Priyanka S. Rana (15136410)

“…Compound A induced a marked decrease in PD-1 surface expression, while no significant change was observed in TIM-3, CTLA-4, and LAG-3.…”

Data Sheet 1_The association between the gut microbiome and antituberculosis drug-induced liver injury.docx by Shengfei Pei (20852069)

“…</p>Results<p>Following anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”

DataSheet1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Table1_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Table 1_The effectiveness of exercise interventions in the improvement of sleep in older adult people: a meta-analysis.docx by Di Geng (1681915)

“…Background<p>Sleep problems are prevalent among the older adult population, with a significant impact on their health and overall well-being. …”

Data Sheet 1_The impact of architectural modifications on relative resistance to fluid flow in ventricular catheters.pdf by Rajesh Kumar Madhavan (20634731)

“…</p>Results<p>With increasing hole and lumen diameter, we found a significant decrease in overall catheter relative resistance using DIH₂0 (P < 0.001 and P < 0.002 respectively, n = 5). …”

Table 1_Food waste management practices in hospital foodservices and their associated greenhouse gas emissions: potential for increased environmental sustainability.docx by Yee Man Janis Yip (21346568)

“…The median GHGs generated decreased after adopting the alternative strategy in all scenarios. …”

Table 1_Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism.xlsx by Yang Yang (45629)

“…Additionally, there was a decrease in osteo-facial fusion and calcified cartilage thickening in the knee joint. …”

Data Sheet 2_Immunometabolic alterations in type 2 diabetes mellitus revealed by single-cell RNA sequencing: insights into subtypes and therapeutic targets.csv by Huahua Li (6896339)

“…</p>Results<p>In patients with T2DM, a marked increase in monocytes and a decrease in CD4+ T cells were observed, indicating immune dysregulation. …”

Table2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Table2_Association of mitochondrial haplogroup H with reduced risk of type 2 Diabetes among Gulf Region Arabs.xlsx by Mohammed Dashti (4849747)

“…</p>Results<p>The analysis revealed a significant protective effect of haplogroup H against T2D (odds ratio [OR] = 0.65; P = 0.022). …”

Image 1_Non-chemotherapy drugs inducing agranulocytosis: a disproportionality analysis based on the FAERS database.pdf by Shanshan Wu (348762)

“…Notably, NCDIA-associated mortality rates showed a significant decrease from 11.91% (2004–2010) to 7.28% (2021–2024) (P < 0.001).…”

Supplementary file 1_Amomum tsao-ko Crevost et Lemarie extract targets the gut-liver axis to combat atherosclerosis in ApoE−/− mice.docx by Qianqian Wang (494839)

“…Serological tests confirmed T-K’s ability to decrease the total serum cholesterol and low-density lipoprotein cholesterol levels. …”

Supplementary file 1_Full-dose versus reduced-dose comparison of direct oral anticoagulants for extended treatment of venous thromboembolism: a systematic review and meta-analysis... by Renshu Zhang (22775495)

“…</p>Conclusion<p>Reduced-dose DOACs were associated with a significant decrease in the risk of major bleeding/CRNMB compared with full-dose DOACs, but were not associated with a significant increase in the risk of recurrent VTE. …”