Search alternatives:
significant effect » significant impact (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
effect decrease » effects decreased (Expand Search)
significant effect » significant impact (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
effect decrease » effects decreased (Expand Search)
-
11261
Image 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1<sup>+</sup> macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”
-
11262
Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif
Published 2025“…Furthermore, univariate and multivariate Cox analysis were used to assess the prognostic effects of ARPs. The investigation of immune cell infiltration and possible functional enrichment followed. …”
-
11263
Table 2_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1<sup>+</sup> macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”
-
11264
Image 3_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…The dynamic mortality risk rate revealed a double peak in the high-risk patients (12 and 48 months) and a single peak in the low–risk patients (24 months) and middle-risk patients (12 months), which gradually decreased over time.</p>Conclusion<p>The SNS staging based on IPI and clinicopathological features can thus be applied to effectively evaluate the OS and DFS of ESCC patients after MIE. …”
-
11265
Image 4_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.tif
Published 2025“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1<sup>+</sup> macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”
-
11266
Table 1_NLR (neutrophil to lymphocyte ratio), PLR (platelet to lymphocyte ratio), and SII (systemic immune-inflammation index) reflect disease activity and renal remission in patie...
Published 2025“…NLR, PLR and SII provided us a quick, simple and cost-effective supervision way in monitoring and managing LN patients.…”
-
11267
Table 1_Single-cell and spatial transcriptomics reveal correlation between RNA methylation-related miRNA risk model and immune infiltration in hepatocellular carcinoma.xlsx
Published 2025“…</p>Discussion<p>Our study reveals that the RMRM risk model could effectively predict the prognosis of HCC, and SPP1<sup>+</sup> macrophages regulated by miR-4739-RNA methylation promote the proliferation and migration of HCC cells. …”
-
11268
Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx
Published 2025“…Furthermore, univariate and multivariate Cox analysis were used to assess the prognostic effects of ARPs. The investigation of immune cell infiltration and possible functional enrichment followed. …”
-
11269
Image 5_Establishment and validation of survival nomogram score staging for esophageal squamous cell carcinoma patients after minimally invasive surgery combined with immune progno...
Published 2025“…The dynamic mortality risk rate revealed a double peak in the high-risk patients (12 and 48 months) and a single peak in the low–risk patients (24 months) and middle-risk patients (12 months), which gradually decreased over time.</p>Conclusion<p>The SNS staging based on IPI and clinicopathological features can thus be applied to effectively evaluate the OS and DFS of ESCC patients after MIE. …”
-
11270
DataSheet2_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF
Published 2025“…Generally, MAN restored the impaired fat anabolism in AIA rats, indicated by increased fat reservoir, leptin and adiponectin secretion, and PPAR-γ and SCD-1 expression. Meanwhile, it decreased circulating IL-1β and IL-6 levels, restored serological lipid profile changes, and relieved oxidative stresses, demonstrating potent therapeutic effects on AIA. …”
-
11271
DataSheet1_α-Mangostin Alleviated Inflammation in Rats With Adjuvant-Induced Arthritis by Disrupting Adipocytes-Mediated Metabolism-Immune Feedback.PDF
Published 2025“…Generally, MAN restored the impaired fat anabolism in AIA rats, indicated by increased fat reservoir, leptin and adiponectin secretion, and PPAR-γ and SCD-1 expression. Meanwhile, it decreased circulating IL-1β and IL-6 levels, restored serological lipid profile changes, and relieved oxidative stresses, demonstrating potent therapeutic effects on AIA. …”
-
11272
SEAwise synthesis of predicted impacts of changes in habitat and spatial management measures suggested in SEAwise for online tool
Published 2025“…Such spatial conservation measures will induce negative short-term effects on the fisheries (e.g.: decreased catches and increased operating costs due to effort displacement to surrounding or distant areas) as well as potentially harmful counterproductive effects on biodiversity in some occurrences. …”
-
11273
Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch...
Published 2025“…</p>Results<p>SFAS significantly improved cardiac function in CHF rats. …”
-
11274
Table 1_Determining the efficacy and safety of acupuncture for the treatment of menstrual migraine: an updated systematic review and meta-analysis.docx
Published 2025“…Compared with control interventions, acupuncture significantly reduced VAS scores, decreased the frequency and duration of migraine attacks, and improved response rates, as well as HIT-6 and MHI scores. …”
-
11275
Image 1_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.tif
Published 2025“…Polygonatum sibiricum polysaccharides (PSP) have demonstrated potential anti-diabetic effects; however, their precise mechanism, particularly through the AMPK-SIRT1 pathway, remains unclear.…”
-
11276
Table 1_Avoiding touching until 60 min—contamination of transdermal estradiol gel after physical contact.docx
Published 2025“…In the estradiol gel group, estradiol levels remained stable within the first 30 min (p >0.05), rapidly decreased at 60 min (p <0.001) and remained stable from 60 min to 120 min (p >0.05). …”
-
11277
Image 4_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
Published 2025“…This meta-analysis aims to compare the antitumor effectiveness and safety profiles of PIBC with PIC.</p>Methods<p>We systematically searched six databases to identify eligible RCTs. …”
-
11278
Table 3_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
Published 2025“…This meta-analysis aims to compare the antitumor effectiveness and safety profiles of PIBC with PIC.</p>Methods<p>We systematically searched six databases to identify eligible RCTs. …”
-
11279
Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs
Published 2024“…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …”
-
11280
Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
Published 2024“…<p>Milk production traits play an important role in dairy cattle breeding, and single nucleotide polymorphisms can be used as effective molecular markers for milk production trait marker-assisted breeding in dairy cattle. …”