Search alternatives:
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
linear decrease » linear increase (Expand Search)
significantly mediate » significantly mediated (Expand Search), significantly predicted (Expand Search), significantly mitigated (Expand Search)
largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
mediate decrease » mean decrease (Expand Search), mediated defense (Expand Search)
linear decrease » linear increase (Expand Search)
-
3381
Table 5_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
-
3382
Table 8_Cardiac energy metabolic disorder and gut microbiota imbalance: a study on the therapeutic potential of Shenfu Injection in rats with heart failure.csv
Published 2025“…</p>Results<p>Myocardial energy metabolism in HF rats was disordered, characterized by reduced fatty acid oxidation, enhanced anaerobic glycolysis of glucose, mitochondrial damage, and decreased ATP content; The gut microbiota of HF rats was imbalanced, with a reduction in beneficial bacteria, an increase in conditional pathogenic bacteria, and impaired intestinal barrier function; Both Shenfu Injection and trimetazidine improved myocardial energy metabolism and cardiac function, but Shenfu Injection was more significant in regulating gut microbiota and improving intestinal health; The production of SCFAs from the gut microbiota of HF rats increased, which may be closely related to myocardial energy metabolism; SCFAs-producing bacteria Akkermansia and Blautia played a key role in the development of HF, and their abundance was positively correlated with SCFAs content.…”
-
3383
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025
Published 2025“…</p><h3>Results</h3><p dir="ltr">Our study shows that temporarily blocking the insulin receptor in young mice leads to later-life liver issues by hindering PPARα-mediated adaptation to a high-fat diet. This is linked to decreased histone active marks at PPARα sites and reduced endogenous PPARα ligands. …”
-
3384
Table 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.docx
Published 2025“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”
-
3385
Presentation 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy coho...
Published 2025“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”
-
3386
Image 1_Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort.pdf
Published 2025“…The modification displayed a quasi-U-shaped distribution in relation to BPA and decreased as TSH levels increased.</p>…”
-
3387
Image 1_Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling.tif
Published 2025“…Combination treatment induced significant G0/G1 cell-cycle arrest, reduced ALDH1⁺ populations, and decreased tumorsphere formation. …”
-
3388
Table 1_Effects of singing on vascular health in older adults with coronary artery disease: a randomized, crossover trial.docx
Published 2025“…When assessing post- to pre- change, the live singing intervention showed a significant change of −0.62 ms<sup>2</sup> (SE 0.29, p = 0.036) in LnHF power.…”
-
3389
Table 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease: a m...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
-
3390
Table 3_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.docx
Published 2025“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”
-
3391
Data Sheet 3_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
-
3392
Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf
Published 2025“…Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”
-
3393
Table 2_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx
Published 2025“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”
-
3394
Genotoxic Mechanisms of Erythrophleum suaveolens Stem Bark Extracts and Fractions in MCF-7 Breast Cancer Cells via Mitochondrial and Non-Mitochondrial Pathways
Published 2025“…After 72 hours, ESSB-treated MCF-7 cells showed a significant (p < 0.05) increase in DNA fragmentation and comet tail DNA percentages (flavonoids induced a 1.21-fold increase in comet tail length). …”
-
3395
Data Sheet 1_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
-
3396
DataSheet1_Neuroprotective effect of Bouvardia ternifolia (Cav.) Schltdl via inhibition of TLR4/NF-κB, caspase-3/Bax/Bcl-2 pathways in ischemia/reperfusion injury in rats.PDF
Published 2024“…This lowers oxidative stress and decreases the expression of proteins and genes linked to cell death, such as Bax, Bcl-2, and caspase-3. …”
-
3397
Table 1_Screening and identification of the H1R antagonists from natural products by BODIPY FL histamine recognition and DPHD-anchored bombardment coupled with target cell extracti...
Published 2025“…Introduction<p>Histamine is an important mediator of allergy, and inhibiting its binding to H1 receptors (H1R) is a key method to alleviate allergic diseases. …”
-
3398
Data Sheet 2_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
-
3399
Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx
Published 2025“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”
-
3400
Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx
Published 2025“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”