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7421
Data Sheet 1_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip
Published 2025“…This study aimed to investigate the protective effects of Aurantii Fructus extract (AFE) on dextran sulfate sodium (DSS)-induced UC in mice and its impact on the gut microbiota.</p>Methods<p>The chemical components of AFE were identified using high-performance liquid chromatography (HPLC). …”
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7422
Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf
Published 2025“…Objective<p>New functional morbidity is common in critically ill children who survive sepsis; yet, the underlying biological mechanisms, particularly the impact of inflammation, remain unknown. We sought to test the hypothesis that increased levels of inflammatory biomarkers during the acute phase of pediatric sepsis are associated with new functional morbidity at hospital discharge.…”
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7423
Image 2_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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7424
Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Despite their growing public health impact in tropical regions, there are currently no specific treatments available. …”
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7425
DataSheet1_Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters.PDF
Published 2024“…In MCF-7/ADR and MDA-MB-231/ADR cells, COP (31 μM) enhanced DOX cytotoxicity with CI (0.77 and 0.75), RR (2.58 and 3.33), and IB suggesting synergism. COP significantly inhibits ABCT function in resistant BC cell lines, increases Rho123 accumulation, and decreases efflux more than VER; 2.1 and 1.2-fold, respectively. …”
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7426
Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Despite their growing public health impact in tropical regions, there are currently no specific treatments available. …”
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7427
Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff
Published 2025“…Despite their growing public health impact in tropical regions, there are currently no specific treatments available. …”
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7428
Image 1_Neonatal supplementation of oleamide during suckling ameliorates maternal postpartum sleep interruption-induced neural impairment and endocannabinoid dysfunction in early a...
Published 2025“…Introduction<p>Postpartum sleep disturbances in women are common and can significantly affect maternal mental health and breastfeeding. …”
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7429
Data Sheet 2_Aurantii Fructus extract alleviates DSS-induced colitis in mice via regulating NF-κB and Nrf2/HO-1 signaling pathways and modulating intestinal microbiota.zip
Published 2025“…This study aimed to investigate the protective effects of Aurantii Fructus extract (AFE) on dextran sulfate sodium (DSS)-induced UC in mice and its impact on the gut microbiota.</p>Methods<p>The chemical components of AFE were identified using high-performance liquid chromatography (HPLC). …”
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7430
Data Sheet 1_Personalized temporal interference stimulation targeting striatum reduces functional stability and dynamic connectivity variability in the sensorimotor network.docx
Published 2025“…</p>Results<p>(1) Functional stability: TI stimulation significantly decreased functional stability in bilateral SMA regions (predominantly SMA proper, with parts of pre-SMA) compared to Sham and baseline conditions (P < 0.01). (2) Dynamic functional connectivity: TI stimulation reduced dFC variability between the right striatum and left SMA region (predominantly SMA proper, with parts of pre-SMA) compared to baseline (P < 0.01). (3) Safety: No adverse cognitive effects or side effects were observed, with good blinding effectiveness maintained throughout the study.…”
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7431
Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model
Published 2025“…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …”
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7432
DataSheet1_Integration of smart charging of large-scale electric vehicles into generation and storage expansion planning: a case study in south china.pdf
Published 2024“…The numerical results show that the implementation of smart charging can significantly alter the decisions of GSEP. As the participation rate of smart charging improves from 0% to 90%, there is an additional 1,800 MW installation in wind and solar power, while the need to build new batteries is noticeably reduced; also, depending on the level of EV uptake, the annualized total system cost decreases by 5.11%–7.57%, and the curtailment of wind and solar power is reduced by 10.34%–19.64%. …”
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7433
Image 1_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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7434
Data Sheet 1_Physical activity of moderate-intensity optimizes myocardial citrate cycle in a murine model of heart failure.pdf
Published 2025“…Interestingly, 8-sWR significantly decreased myocardial citrate content in the presence of unchanged myocardial [BCAAs], ETC proteins content and mtDNA copy number.…”
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7435
Image 2_Yishen-Huoxue formula alleviates renal interstitial fibrosis by attenuating hypoxia-induced renal cell injury and promoting angiogenesis via miR-210/HIF-1α pathway.jpeg
Published 2025“…</p>Results<p>In vivo, YHF treatment significantly attenuated RIF, protected renal function, increased miR-210 expression, and decreased the expression of HIF-1α, BNIP3, and NIX in the serum exosomes of UUO rats. …”
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7436
Figure S1-S21 from miR-196b-5p Regulates Colorectal Cancer Cell Migration and Metastases through Interaction with HOXB7 and GALNT5
Published 2024“…Three independent biological experiments were performed and the means and standard deviations are shown (* = significant, p < 0.05; **, p < 0.01; ***, p < 0.001). …”
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7437
Table2_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.xlsx
Published 2024“…Among the dominant bacterial phyla, the medium ratio of organic substitution treatment significantly increased the relative abundances of Proteobacteria (by 3.57%) and Actinomycetes (by 14.94%), and decreased the relative abundances of Acidobacteria (by 5.18%) and Planctomycetes (by 7.76%) compared with no fertilization, while the dominant fungal phyla did not respond significantly to the addition of organic fertilizer. …”
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7438
Table1_Short-term organic fertilizer substitution increases sorghum yield by improving soil physicochemical characteristics and regulating microbial community structure.docx
Published 2024“…Among the dominant bacterial phyla, the medium ratio of organic substitution treatment significantly increased the relative abundances of Proteobacteria (by 3.57%) and Actinomycetes (by 14.94%), and decreased the relative abundances of Acidobacteria (by 5.18%) and Planctomycetes (by 7.76%) compared with no fertilization, while the dominant fungal phyla did not respond significantly to the addition of organic fertilizer. …”
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7439
Table 1_Correlation between lactate/albumin ratio and 28-day mortality in sepsis-associated acute kidney injury patients.docx
Published 2025“…The Kaplan–Meier curves showed that participants having elevated LAR exhibited significantly decreased survival rates. Cox proportional hazards models showed that higher LAR was related to higher 28-day death rate in SA-AKI patients (HR: 1.224, 95% CI: 1.160–1.291, p < 0.001). …”
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7440
The number of male–male agonistic interactions in relation to females with maximal swelling.
Published 2025“…<b>(D)</b> Visualization of the interdependency between the number of males and females with maximal swelling on the male aggression rate (significant interaction in LM-2E) shows that when there were a greater number of males in the party, e.g., Mean + 1SD (9.6 males in D), the male aggression rate decreased as the number of females with maximal swelling increased. …”