CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells. by Jovana Deretic (13113617)

“…The mean cilia length in CCDC66-depleted cells decreased to 0.67-fold compared to the mean control length. …”

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…<p dir="ltr"><b>I</b><b>NTRODUCTION</b></p><p dir="ltr">Trimethylamine N-oxide (TMAO) is a small organic molecule found at osmotically-significant concentrations in many marine animal taxa. …”

Table 1_Effect of ticagrelor combined with metoprolol extended-release tablets on cardiac function and clinical prognosis in elderly patients with acute coronary syndrome after per... by Lili Wang (104605)

“…The incidence of adverse prognostic events in the OG was significantly lower at 8.89%, compared to 37.78% in the CG (P < 0.05).…”

Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Data Sheet 1_Comparison of intravascular imaging, physiological assessment and angiography for coronary revascularization in acute coronary syndrome: a systematic review and networ... by Xuan-Yan Liu (19362096)

“…The primary outcome for this research was major adverse cardiovascular events (MACE) occurrences. Each PCI strategy was ranked as per the risk ratio (RR) at the 95% confidence interval (95% CI) for developing MACE.…”

Supplementary file 1_Therapeutic efficacy and safety of Xuebijing in traumatic brain injury: systematic review and meta-analysis.docx by Yihan Sun (3432287)

“…No significant increase in adverse drug events (ADEs) was observed (RR = 1.32, 95% CI 0.58–2.96). …”

Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Table 1_Targeting nail psoriasis: IL-17A inhibitors demonstrate site-specific superiority over IL-23 inhibitor in a 24-week dermoscopy-guided real-world cohort.docx by Xiamei Yan (21014921)

“…Safety was monitored through treatment-emergent adverse events (TEAEs).</p>Results<p>(1) By week 24, PASI, BSA, DLQI and NAPSI scores had significantly decreased from baseline in all groups (P<0.001). (2) By week 24: SEC, IXE, and GUS groups saw nail matrix NAPSI score improvements of 65.9%, 60.5%, and 51.5%, with 68%, 55%, and 30% achieving NAPSI 60; Nail bed NAPSI score improvements were 58.8%, 68.6%, and 65.8%, with 28%, 65%, and 40% achieving NAPSI 60; Total NAPSI score improvements were 62.7%, 64.6%, and 53.7%, with 44%, 70%, and 30% achieving NAPSI 60. (3) All patients in the SEC and IXE groups achieved PASI 75, compared to 85% in the GUS group. …”

Data Sheet 1_Efgartigimod for generalized myasthenia gravis in the extreme elderly (≥80 years): a multicenter retrospective real-world study.pdf by Ye Hong (2580841)

“…At week 4 (1week after the final infusion), the study showed significant reductions in all efficacy measurements: MG-ADL scores decreased by 52.2% ± 30.8% (from 10.9 ± 2.7 to 3.6 ± 2.1), QMG scores by 36.6% ± 28.4% (from 18.2 ± 7.0 to 11.7 ± 8.3), MGC scores by 48.2% ± 33.4% (from 17.8 ± 7.5 to 9.0 ± 8.6). …”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…On the contrary, increased snow depth decreased C source strength inside the exclusion offsetting the difference between reindeer grazing treatments. …”

Data Sheet 1_Brain injury, endocrine disruption, and immune dysregulation in HIV-positive men who have sex with men with late HIV diagnosis.docx by Yihui He (2936874)

“…These imaging findings were significantly correlated with endocrine, immune, and clinical variables.…”

Data_Sheet_1_Long-term phenobarbital treatment is effective in working-age patients with epilepsy in rural Northeast China: a 10-year follow-up study.docx by Rongxin Li (3552779)

“…Seizure frequency, self-efficacy, adherence, and adverse events (AEs) were assessed monthly.</p>Results<p>Of the 3,568 participants, 288 (8.1%) withdrew from the study and 159 (4.5%) died. …”

Table1_Radiotherapy plus lenvatinib versus radiotherapy plus sorafenib for hepatocellular carcinoma with portal vein tumor thrombus: a retrospective study.docx by Min Zhang (111999)

“…The most common adverse events were myelosuppression, decreased liver function, fatigue, diarrhea, nausea, and vomiting. …”

Multicomponent physical exercise program among community-dwelling older adults who are users of home care services: a quasi-experimental pilot study by Aida Ruiz-Fernández (22822586)

“…Frailty decreased on both scales (OR = 0.142 and 0.125). No further significant effects were observed.…”

Data Sheet 1_Efficacy and safety of PCSK9 inhibitors, potent statins, and their combinations for reducing low-density lipoprotein cholesterol in hyperlipidemia patients: a systemat... by Yuhua Jiang (10300159)

“…Moreover, the incidence of adverse events (AEs) was similar to that observed in the control group, which included both placebo and potent statin groups, with no significant differences identified in our study (P > 0.05).…”

Supplementary file 3_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The incidence of asthma-related adverse events was 13.3% (mild wheezing and coughing), which did not interrupt training. …”

Supplementary file 2_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The incidence of asthma-related adverse events was 13.3% (mild wheezing and coughing), which did not interrupt training. …”

Supplementary file 6_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The incidence of asthma-related adverse events was 13.3% (mild wheezing and coughing), which did not interrupt training. …”

Supplementary file 1_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The incidence of asthma-related adverse events was 13.3% (mild wheezing and coughing), which did not interrupt training. …”

Supplementary file 5_Development and preliminary clinical feasibility of a Delphi-based aerobic exercise prescription for children with asthma.docx by Ying Zhang (40767)

“…The incidence of asthma-related adverse events was 13.3% (mild wheezing and coughing), which did not interrupt training. …”