بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
linked decrease » marked decrease (توسيع البحث)
linear decrease » linear increase (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
linked decrease » marked decrease (توسيع البحث)
linear decrease » linear increase (توسيع البحث)
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21061
Image 4_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
منشور في 2025"…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…"
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21062
Table 2_Tackling global inequalities in maternal hypertensive disorders: trends and the impact of public health emergencies, 1990–2021.csv
منشور في 2025"…However, the pandemic significantly slowed the decline in low- and low-middle SDI regions.…"
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21063
Table 3_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an...
منشور في 2025"…The most frequent grade 3–5 AEs in the PIBC group included anorexia (36.40%), decreased neutrophil count (16.25%), neutropenia (13.50%), reduced white blood cell count (12.12%), and febrile neutropenia (9.42%).…"
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21064
Supplementary data: Characterization of medical device randomized controlled trials with adaptive designs
منشور في 2024"…The average annual number of adaptive RCTs per 1000 clinical trials was the highest (8.55 ± 11.65) during 2005–2010, reduced to 3.33 ± 2.35 during 2011–2016, and significantly decreased to 1.29 ± 0.85 during 2017–2024 (p = 0.011). …"
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21065
Image 3_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff
منشور في 2025"…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …"
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21066
Image 4_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.tif
منشور في 2025"…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …"
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21067
Table 1_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
منشور في 2024"…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …"
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21068
Image 4_Prediction of major adverse cardiovascular events following ST-segment elevation myocardial infarction using cardiac obesity marker—epicardial adipose tissue mass index: a...
منشور في 2025"…Background<p>Although reperfusion therapy has led to improvements in the acute phase of ST-segment elevation myocardial infarction (STEMI), the incidence of major adverse cardiovascular events (MACE) following STEMI has not significantly decreased. The accumulation of epicardial adipose tissue (EAT) may be associated with poorer STEMI prognosis and could serve as a potential prognostic marker. …"
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21069
Image 4_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co...
منشور في 2025"…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …"
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21070
Table 3_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx
منشور في 2025"…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
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21071
Table 6_Association of SPP1 and NCAPG genes with milk production traits in Chinese Holstein cows: polymorphism and functional validation analysis.xlsx
منشور في 2024"…Association analysis showed that all six SNPs were significantly associated with milk protein percentage. …"
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21072
Table 1_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx
منشور في 2025"…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …"
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21073
Image 3_HIV risk and influence factors among MSM who had sought sexual partners in core venues: a continuous sentinel surveillance in 2010–2022.png
منشور في 2024"…</p>Conclusion<p>Following the implementation of differentiated venue-based interventions, the risk of HIV among MSM who had sought sexual partners in core venues decreased to a level comparable to that of MSM who had not. …"
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21074
Experiences communicating in noise with aphasia (Harmon et al., 2024)
منشور في 2024"…</p><p dir="ltr"><b>Results: </b>Quantitative findings showed that people with aphasia reported significantly greater perceived effort and stress than controls. …"
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21075
Data Sheet 4_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway....
منشور في 2025"…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
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21076
The role of Cathepsin inhibitors in RGC damage in hypoxic retina.
منشور في 2025"…Treatment with neither Odanacatib nor SID26681509 reduced the percentage of PI-positive RGCs, whereas the positive control SNJ-1945 significantly decreased the percentage. Data are means ± SD (n = 3). …"
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21077
Data Sheet 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.pdf
منشور في 2025"…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …"
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21078
Behavior is best fit by models with independent attributes.
منشور في 2025"…Positive/negative coefficients on option A/B indicate that the probability of choosing option A increases/decreases with the magnitude of that attribute. Larger deviations from 0 are indicative of more influence on the choice. …"
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21079
Table 1_Hypothalamic FTO upregulates BDNF to promote GnRH expression through the PI3K/Akt pathway, leading to precocious puberty.docx
منشور في 2025"…</p>Results<p>Hypothalamic GnRH and FTO expression progressively increased whereas m6A methylation decreased during puberty. MeRIP-seq revealed significantly reduced m6A methylation of Bdnf mRNA in the arcuate nucleus (ARC) of female rats during early puberty. …"
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21080
Data Sheet 2_A Delphi-based framework for optimizing nurse staffing in Chinese hospitals.docx
منشور في 2025"…The primary objectives of this optimization process include reducing nurse workload, improving job satisfaction, and decreasing turnover rates, all of which facilitate improved patient outcomes.…"