Search alternatives:
significantly impairs » significantly impacts (Expand Search), significantly impact (Expand Search), significantly improves (Expand Search)
linked decrease » marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
significantly impairs » significantly impacts (Expand Search), significantly impact (Expand Search), significantly improves (Expand Search)
linked decrease » marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
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Oxidative imbalance linked to impaired mitochondrial bioenergetics mediates the toxicity of mesoionic compounds MI-D and MI-J in hepatocarcinoma cells (HepG2)
Published 2025“…Mesoionic compounds MI-D and MI-J have shown potential for treating HCC due to their significant toxicity to these cells. This study investigated whether this toxicity is linked to their effects on oxidative balance in HepG2 cells cultured in high glucose (HG-glycolysis-dependent) and galactose plus glutamine supplemented (GAL-oxidative phosphorylation-dependent) DMEM medium. …”
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Flowchart of the study population.
Published 2025“…Among those 803 individuals who did not take antihypertensive medication, there was a significant association in linear regression between increase in PSS-10 and decrease in C2 (B: −0.2, 95% CI: −0.4- −0.02; p = 0.03) that was lost after adjustment for physical activity (B: −0.16, 95% CI: −0.35–0.03; p = 0.1). …”