بدائل البحث:
lives disease » virus disease (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
lives disease » virus disease (توسيع البحث)
decrease » decreased (توسيع البحث), increase (توسيع البحث)
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…MethodsWe used the 2019 Global Burden of Disease (GBD) data for estimates of prevalence, years lived with disability (YLDs), and underlying causes of HF in the EMR. …"
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
منشور في 2023"…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …"
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Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019
منشور في 2020"…The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. …"
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Being female with vitiligo disease in traditional societies within North Africa
منشور في 2024"…This validated tool measures the impact of skin disease on several aspects of an individual’s life, including physical, emotional, and social well-being. …"
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COVID‐19 effect on patients with noncommunicable diseases: A narrative review
منشور في 2022"…<h3>Background and Aims</h3><p dir="ltr">On March 11, 2020, the WHO has declared COVID‐19 a global pandemic, affecting our day‐to‐day lives. Physical distancing and lockdown made significant obstacles to populations, particularly healthcare systems. …"
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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease
منشور في 2023"…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …"
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Anti-amyloid monoclonal antibody therapies in Alzheimer’s disease – a scoping review
منشور في 2025"…Addressing these gaps is critical in ensuring safe, effective, and equitable treatment for all patients living with Alzheimer’s disease.</p><h2>Other Information</h2><p dir="ltr">Published in: Neuroscience<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" rel="noreferrer" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://doi.org/10.1016/j.neuroscience.2025.10.011" rel="noreferrer noopener" target="_blank">https://doi.org/10.1016/j.neuroscience.2025.10.011</a></p>…"
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Relationship between pharmaceutical pricing strategies with price, availability, and affordability of cardiovascular disease medicines: surveys in Qatar and Lebanon
منشور في 2022"…When lifestyle modifications prove insufficient, medication becomes a cornerstone in controlling such diseases and saving lives. Price, availability, and affordability hinder the equitable access to medicines. …"
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
منشور في 2024"…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …"
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10-year cardiovascular disease risk and its predictors: a comparison between healthcare workers and the general public in Qatar
منشور في 2025"…Lifestyle emerged as the main independent predictor for higher ASCVD risk in both groups. Additionally, living alone and being a nurse were significant independent predictors of higher risk among HCWs. …"
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The Next Decade of Cardiovascular Disease Burden in Qatar, a Gulf Cooperation Council Country: Projections from 2024 to 2033
منشور في 2025"…<h3>Background</h3><p dir="ltr">Cardiovascular diseases (CVD) are a great public health challenge in Qatar, with significant impacts on long-term population health and societal costs. …"
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PFDI: a precise fruit disease identification model based on context data fusion with faster-CNN in edge computing environment
منشور في 2023"…<div><p>Fruits significantly impact everyday living, i.e., Citrus fruits. …"