Table 3_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel... by Jingjian Dong (12458730)

“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”

<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian... by Silvia Torchio (611349)

“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca²⁺ fluxes due to altered transcription of Ca²⁺-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …”

Table 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Image 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Table 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Table 4_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Table 3_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Image 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”

Metabolite changes between pathways in <i>Salmonella</i> cells in biofilm and planktonic states. by Yuliany Guillín (20614081)

<b>Increasing ECM tree dominance enhances </b><b>soil </b><b>lignin </b><b>phenols </b><b>but suppresses microbial necromass contribution to soil organic carbon in a subtropical </... by Lu Mengzhen (20146224)

“…Our results indicated that ECM% did not affect SOC content but significantly altered SOC composition. Specifically, a higher ECM% promoted accumulation of plant-derived C and reduced microbial-derived C. …”

Bird’s own song is similarly represented by NCM neurons when sung or played back a) Schematic of behavioral contexts. b-e) Effect of behavioral context on response properties of ne... by Daniel J. Pollak (14593065)

“…Asterisks indicate significance of <b>p</b> <  0.05. Dots indicate individual neurons, horizontal lines indicate mean, and thin vertical lines indicate 95% confidence intervals.…”

Supplementary Material for: Effect of Amla extract on Body Mass Index, waist circumference, total body fat, visceral fat, skeletal muscle mass, body age and related parameters: A r... by figshare admin karger (2628495)

“…Results: Supplementation with 1 gram of AMX-160 (500 mg twice daily) significantly (p<0.05) reduced visceral fat, increased skeletal muscle mass, and decreased subcutaneous fat. …”

Data Sheet 1_Global burden of breast cancer and application of patient-reported outcomes in clinical trials: a systematic analysis based on the global burden of disease study 2021... by Jiaxin Hao (18837682)

“…Background<p>Breast cancer is one of the most prevalent tumors worldwide, significantly compromising the survival and quality of life of patients. …”

Table 1_Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and... by Yaqi Yin (7280069)

“…Supplementation with folic acid plus vitamin B12 (SMD = −2.77, 95% CI [−3.23, −2.30], P < 0.0001) significantly reduced serum homocysteine levels and decreased the incidence of total complications (RR = 0.30, 95% CI [0.24, 0.38], P < 0.0001). …”

Supplementary file 1_Comparative effects of high-intensity interval training versus moderate-intensity continuous training on body composition and blood pressure in overweight adol... by Xilin Li (1913320)

“…</p>Conclusion<p>Both HIIT and MICT demonstrated comparable effects on most outcomes in overweight/obese adolescents. HIIT showed a modest, borderline significant advantage in reducing body fat percentage, while MICT appeared more effective in reducing waist circumference in the running subgroup. …”

Data Sheet 1_Global, regional, and national burden and trends of intracerebral hemorrhage among adolescents and young adults aged 15–39 years from 1990 to 2021: a comprehensive tre... by Xuanchen Liu (12188147)

“…Background<p>Intracerebral hemorrhage (ICH) poses a significant health challenge, notably affecting adolescents and young adults (AYAs) aged 15–39 years. …”

Multiomics Identified the Nutritional Improvement in LAB-Fermented Goat Milk by Liyan Ge (13017372)

“…Lactic acid bacteria (LAB) in fermented goat milk (FGM) significantly alter its composition, though their effect on goat milk’s nutritional profile is not well understood. …”

<b>Association between myristic acid in plasma triglycerides and metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes: A comprehensive analysis... by Shigero Hosoe (21735020)

“…After comprehensive diabetes treatment for 2 weeks, FA levels in many TGs significantly decreased; especially, FA 14:0 levels in TGs decreased notably, and this reduction was more pronounced in patients with MASLD.…”

Table1_Assessing physical fitness adaptations in collegiate male soccer players through training load parameters: a two-arm randomized study on combined small-sided games and runni... by YanXiu Quan (19645810)

“…Although there were positive trends in variables such as RSA and 30-15IFT, these changes were modest and not statistically significant. The results suggest that while the combined SSGs and HIIT approach shows potential, its impact on physical fitness over a 4-week period is limited, with some variables, like CMJ, even showing decreases.…”

<i>Stenotrophomonas</i> sp. SI-NJAU‑1 and Its Mutant Strain with Excretion-Ammonium Capability Promote Plant Growth through Biological Nitrogen Fixation by Mengjia Zhou (4330429)

“…Additionally, SI-NJAU-1 was proven to decrease the application of compound fertilizers by 30%. …”