DataSheet1_Type I-conventional dendritic cells support the progression of multiple myeloma in the bone marrow.docx by Sayaka Suzuki (248729)

“…Consequently, the frequencies of exhausted CD8 T cells and regulatory T cells significantly decreased in the bone marrow of cDC1-depleted mice.…”

Ameliorative impact of Juniperus Macrocarpa extract on methotrexate-induced hepatic damage in rats by Shahad Hassan Hadi (20141025)

“…Rats in groups 3 and 4 were given daily dosages of 100 mg and 200 mg of Juniperus macrocarpa aqueous extract, respectively, for two weeks before receiving a single intraperitoneal MTX injection. Juniperus macrocarpa extracts at both low and high doses substantially alleviated the MTX-provoked biochemical alterations, as evidenced by decreased levels of inflammatory parameters including TNF-α and IL-6 and hepatic enzymes including ALT, AST, and ALP. …”

Data Sheet 1_Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis.pdf by Zige Liu (20724752)

“…Cordycepin pre-treatment significantly reduced ROS levels and XO activity, inhibited the expression of NLRP3, cleaved-Caspase-1, and cleaved-GSDMD, and decreased pyroptosis-associated inflammatory cytokines IL-1β and IL-18, along with Caspase-1 activity. …”

3-D burrow morphology of <i>Chondrites targionii</i> (Brongniart, 1828) from an Upper Jurassic firmground of Southern Germany by Franz-Josef Scharfenberg (13134765)

“…With intermediate effect size, statistically compared branch widths revealed significantly decreasing widths from unbranched tunnels over root branches to their side branches, which, along with the scale-leaf-shaped structures, may indicate a vermiform tracemaker. …”

Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy by Jiayu Zhang (128702)

“…Key findings revealed 22 differentially expressed proteins (DEPs) when comparing the PDR and IMH groups, with 21 proteins showing increased expression and only one demonstrating decreased levels. Among these DEPs, fibroblast growth factor 23 (FGF23) emerged as a particularly promising candidate, as elevated expression was observed in retinal tissue from both diabetic (db/db) mice and the high-glucose (HG) or glyoxal-treated Müller glia (MG) cultures. …”

Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf by Miles Anderson-Watters (20626604)

“…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”

Data Sheet 1_Formononetin promotes porcine oocytes maturation and improves embryonic development by reducing oxidative stress.zip by Na Wang (193263)

“…It also increased mitochondrial function and ATP levels, reduced intracellular reactive oxygen species, and elevated intracellular GSH levels in both oocytes and embryos. Moreover, FMN significantly decreased autophagy and apoptosis levels in blastocyst cells, potentially via regulation of the Nrf2/Keap1 pathway. …”

Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx by Ahmed Alsafar (21716735)

“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”

Measurement of interference efficiency of AjNLRC4 or AjCASP-1 by specific siRNA transfection. by Kaiyu Chen (11691918)

“…It was found that after the above treatment, the mRNA and protein levels of AjNLRC4 were significantly decreased. Results are representative of at least three independent experiments, and error bars denote the SD of triplicate wells. …”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”

Changes in the separation and spread of evidence distributions induced by energy, contrast, and variability manipulations. by Medha Shekhar (19502698)

“…*p<0.05; **p<0.01; ***p<0.001; ****p<0.0001; n.s., not significant.</p>…”

Routine blood biochemical biomarkers in amyotrophic lateral sclerosis: Systematic review and cohort analysis by Robert J. Nona (18558903)

“…To provide further information about the roles of these four biomarkers roles we performed a systematic review. In addition, we also performed a new study of the role of these biomarkers in predicting survival, using data from our local ALS cohort. …”

Data Sheet 1_Real-time evaluation of antibacterial efficacy using bioluminescent assays for Pseudomonas aeruginosa and Staphylococcus aureus.pdf by Manali Patil (22142128)

“…Treatment with cefotaxime resulted in a significant reduction of the bioluminescent signal in P. aeruginosa compared to untreated controls, while doxycycline induced a delayed growth curve. …”

Figure 5 from Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment–dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors by Eleonora Y. Khlebus (20814571)

“…Colors of heatmap display gene expression <i>Z</i>-scores that are computed on a gene-by-gene basis: Increased expression (red) and decreased expression (blue). …”

The components of Qili Qiangxin capsule. by Minyan Sun (19751378)

“…QLQX treatment for 28 days significantly improved cardiac function, as evidenced by decreases in heart mass index, cardiac volume, left ventricular end-diastolic diameter, left ventricular end-systolic diameter, N-terminal B-type natriuretic peptide levels, and high-sensitivity cardiac troponin I levels and increases in left ventricular ejection fraction and left ventricular fraction shortening. …”

Single-cell RNA-seq dataset of innate lymphoid cells by Sijie Chen (12510043)

“…Our research, along with others’, indicates a high proportion of LTi cells in the fetal ILC pool, which significantly decreases after birth. …”

Data Sheet 5_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Data Sheet 4_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Data Sheet 2_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”

Data Sheet 3_Global, regional, and national burden of IHD attributable to PM pollution aged 70 and above: an age-period-cohort modeling and frontiers analysis study.csv by Ke-Jie He (13239966)

“…Background<p>Particulate matter (PM) pollution is a significant risk factor for ischemic heart disease (IHD). …”