Downregulation of <i>TcPiezo1</i> expression decreases Ca²⁺ entry in <i>T. cruzi.</i> by Guozhong Huang (673424)

“…(B) Downregulation of <i>TcPiezo1</i> expression showed a significant decrease of intracellular Ca²⁺ (+Tet). …”

Diagram of SEIRV model of yellow fever transmission in humans showing zoonotic transfer from the sylvatic non-human primate reservoir (mediated by the λ_<i>S</i> paramete... by Keith Fraser (1868587)

KIF15 mediates the trafficking of PSD95 along microtubules. by Xiaomei He (795333)

Primers used for SACMV DNA-A and DNA-B virulence proteins and PacBio SMRT sequence of NLR and LRR-PK/PL genes. by Bulelani L. Sizani (21485746)

Expression levels of SACMV DNA-A and DNA-B encoded virulence factors in TME3 and T200 at 12, 32 and 67dpi measured by RT-qPCR. by Bulelani L. Sizani (21485746)

Data for Figs 8A–8H, 9A–9K, 10A–10I. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Inflammatory and microbial-derived signals are unable to restrict IL-33 mediated expansion of trTregs <i>in vitro</i>. by Santiago Boccardo (5927954)

5-HT supplementation induces mitochondrial damage. by Li Gao (131516)

South African cassava mosaic virus (SACMV) genome structure and the effect of SACMV on cassava leaf symptoms. by Bulelani L. Sizani (21485746)

Transcript levels of MAPK, NIK, NLR and SA-depended gene pathways and responsive genes. by Bulelani L. Sizani (21485746)

Structure-based alignment and homology modelling of MeTIR domains. by Bulelani L. Sizani (21485746)

Transcript levels of MAPK, NIK, NLR and SA-dependent gene pathways and responsive genes. by Bulelani L. Sizani (21485746)

Differentially-expressed NLR genes in susceptible T200 and tolerant TME3 genotypes infected with SACMV. by Bulelani L. Sizani (21485746)

Expression profile of WRKY-TFs and ROS accumulation in susceptible T200 and tolerant TME3 cassava genotypes. by Bulelani L. Sizani (21485746)

Hypothetical model of the molecular mechanism underlying the ability of SACMV to suppress the host RNA silencing mechanism (PTGS) and systemic acquired resistance (SAR). by Bulelani L. Sizani (21485746)

Total count of HiFi reads indicating gene variation in 24 cassava genotypes. by Bulelani L. Sizani (21485746)

Details of the GWAS data in this study. by Jing Wang (6206297)

“…The effect of anti-H. pylori IgG seropositivity on CHD may be related to a higher peak insulin response or lower total free cholesterol levels and a decrease in waist circumference and waist-to-hip ratio. …”

Active DNA Demethylation Mediated by <i>OsGADD45a2</i> Regulates Growth, Development, and Blast (Magnaporthe oryzea) Resistance in Rice by Ganghua Zhou (9283406)

“…In <i>OsGADD45a2</i> overexpression lines, significant decreases in CG and CHG methylation levels were observed in protein-coding genes, leading to their upregulation. …”

Data for Fig 6D. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Data for Fig 5D. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”