Image 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.pdf by Maxim Sorokin (4379848)

“…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …”

Workflow of the study. by Hongliang Chen (538815)

“…Enrichment and immune infiltration analyses revealed significant differences in mitochondrial structure and function, immune cell disorders, and signaling pathway activation between the high- and low-mitochondrial gene expression UC groups. …”

Table 1_Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins.docx by Min Luo (258201)

“…Western blot analysis validated these findings in plasma samples, showing significantly increased expression of MMP12 and ASM, and decreased expression of NPNT and SNX1 in COPD patients compared to healthy controls, while KLC1 showed no significant difference. …”

DataSheet8_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.zip by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

What is the optimal In2Care stations density to achieve Aedes aegypti population reduction in a dengue endemic setting? by Rafael Freitas (16738416)

“…</p><p dir="ltr"><b>Conclusions/Significance:</b> The density of In2Care stations varied across neighborhoods, ranging from 220 to 555 stations per km². …”

Table 1_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.docx by Guojie Ji (21518650)

“…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …”

Investigation of changes in the choice reaction time with levodopa in patients with Parkinson’s disease by Halil Onder (10368032)

“…The comparative analyses between medication-off and -on states revealed that the MDS-UPDRS-3 scores decreased significantly during the medication-on states (<i>p</i> < 0.001, d = 1.09). …”

Data_Sheet_1_Correlation between body mass index and gender-specific 28-day mortality in patients with sepsis: a retrospective cohort study.docx by Chong Li (120471)

“…</p>Results<p>The BMI and 28-day mortality exhibited an L-shaped relationship (p for nonlinearity <0.001) with significant gender-specific differences. Subgroup analysis revealed different association patterns between the male and female cohorts. …”

Table 2_Role of miR-144-5p in modulating lipid metabolism and potentially alleviating obesity via the PGC-1α/AMPK pathway.xlsx by Siriguleng Yu (14555900)

“…</p>Results<p>The treatment significantly reduced diet-induced adiposity and decreased inflammatory responses. …”

Table 2_Circulating growth differentiation factor-15 concentration and hypertension risk: a dose-response meta-analysis.docx by Zhengqing Yu (12641890)

“…Significant heterogeneity was detected in the pooled analysis and meta-regression analysis suggested that participants’ age and the prevalence of diabetes significantly accounted for the heterogeneity.…”

Neurodevelopmental H2AK119ub enrichment within H3K4me3-positive promoters subdues transcription. by Aditya Parmar (22331873)

“…<b>(J)</b> RNAseq data within genes possessing H3K4me3-only promoters that experienced a significant increase in H2AK119ub. <b>(K)</b> RNAseq data within genes possessing bivalent promoters that experienced a significant increase in H2AK119ub. …”

Table 1_Trends in diet structural composition and quality among adults in Beijing, China (2010–2022).docx by Ningsu Chen (18014155)

“…Between 2010 and 2022, carbohydrate contribution to energy intake decreased from 56.1 to 46.7%, whereas fat intake increased from 31.6 to 36.9%. …”

Table 1_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.xlsx by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Image3_A novel functional IKBKE variant activating NFAT in a patient with polyarthritis and a remittent fever.jpeg by Saeko Yamada (11899439)

“…RNA-seq of peripheral blood immune cell subsets revealed significant differences in gene expression, especially in T cells.…”

Effects of nano-curcumin on cell cycle and apoptosis in breast cancer cells. by Taraneh Givi (22793530)

“…The expression levels of <i>CCNA2</i> and <i>CCND1</i> were significantly decreased in both MCF7-S and MCF7-TR cells following nano-curcumin treatment. …”

Image 4_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”

Table 2_Outcomes after therapeutic SBE-ERCP for choledochojejunal/hepaticojejunal anastomotic stenosis after bile duct injury.docx by Yijun Shu (3456728)

“…Background<p>Choledochojejunal/hepaticojejunal anastomotic stenosis (CJS/HJS) is significant clinical problem associated with decreased survival postsurgery. …”

Data Sheet 3_Global trends in esophageal cancer: sex and age disparities in health inequalities from 1990 to 2021, with projections to 2050.pdf by Ying Liu (18461)

“…Background<p>Esophageal cancer remains one of the deadliest cancers globally, highlighting significant health challenges and socioeconomic disparities. …”

Effect of urea and K₂SO₄ on enzyme activity and biochemical changes of date fruit (<i>Phoenix dactilyfera</i> cv. ‘Zahedi’) during ripening by Narjes Fahadi Hoveyze (22376779)

“…</p> <p>The activity of PME, PG, cellulase, and invertase exhibited a significant elevation during date fruit ripening, and conversely, POX and PPO activity decreased.…”

Image 1_Inonotus obliquus (chaga) ameliorates folic acid-induced renal fibrosis in mice: the crosstalk analysis among PT cells, macrophages and T cells based on single-cell sequenc... by Yueling Peng (20877587)

“…Histological analysis revealed that Chaga treatment significantly reduced renal tubular damage scores [from 5.00 (5.00, 5.00) to 2.00 (2.00, 2.00), p < 0.05] and decreased collagen deposition area (from 11.40% ± 3.01% to 4.06% ± 0.45%, p < 0.05) at day 14. …”