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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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lower decrease » linear decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
larger decrease » marked decrease (Expand Search)
lower decrease » linear decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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20501
Table 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20502
Image 5_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif
Published 2025“…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …”
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20503
Table_5_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.DOCX
Published 2024“…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …”
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20504
Data Sheet 4_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20505
Data Sheet 3_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx
Published 2024“…The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …”
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20506
Semaglutide ameliorates diabetes-associated cognitive dysfunction in mouse model of type 2 diabetes
Published 2025“…</p><p dir="ltr"><b>Results:</b> Semaglutide treatment significantly reduced blood glucose levels in diabetic mice. …”
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20507
Table 1_The evolution of three-dimensional knee kinematics after ACL reconstruction within one year.docx
Published 2025“…The recovery rates and patterns differ significantly across dimensions, with some abnormalities not fully corrected within one-year post-urgery. …”
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20508
DataSheet2_Sodium danshensu modulates skeletal muscle fiber type formation and metabolism by inhibiting pyruvate kinase M1.pdf
Published 2024“…Muscle mass, the percentage of slow oxidative fibers, succinic dehydrogenase activity, muscle endurance, glucose tolerance, and the expression of the MyHC1 and MyHC2a genes increased while MyHC2b expression, lactate dehydrogenase activity, and the percentage of glycolytic muscle fibers decreased in SDSS-treated mice. Mechanistically, SDSS bound to the pyruvate kinase PKM1 and significantly repressed its activity. …”
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20509
Table 1_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.xlsx
Published 2025“…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …”
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20510
Data Sheet 5_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20511
Table 1_Effectiveness of Mindfulness and Qigong Training for Self-Healing in patients with Hwabyung and depressive disorder: a randomized controlled trial.docx
Published 2025“…</p>Results<p>MQT-SH significantly decreased Hwabyung, depression, anxiety, and anger while increasing subjective vitality, and the effectiveness of the intervention were maintained at a short-term follow-up of 6 weeks. …”
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20512
Image 1_Hyodeoxycholic acid modulates gut microbiota and bile acid metabolism to enhance intestinal barrier function in piglets.tif
Published 2025“…The results demonstrated that HDCA administration at 0.2 mg/mL suppressed body weight gain in piglets, which was alleviated by FMT. HDCA significantly altered gut microbiota composition in SPF piglets, markedly increasing the Lactobacillus abundance (37.97% vs. 5.28% in SPF-CON) while decreasing the proportion of Streptococcus (28.34% vs. 38.65%) and pathogenic family Erysipelotrichaceae (0.35% vs. 17.15%). …”
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20513
Data Sheet 3_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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20514
Data Sheet 8_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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20515
Data Sheet 5_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.zip
Published 2025“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca<sup>2+</sup> fluorescence intensity and the expression of the IP<sub>3</sub>R-VDAC-MCU complex in MPP<sup>+</sup>-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”
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20516
Table 1_The expanding role of 16s ribosomal RNA PCR in the management of patients with infective endocarditis undergoing cardiac surgery.docx
Published 2024“…The sensitivity of both valve culture and 16srRNA decreased significantly with prolonged preoperative antibiotic therapy. …”
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20517
Image_2_Effects of clear corneal incision location and morphology on corneal surgically induced astigmatism and higher-order aberrations after ICL V4c implantation.JPEG
Published 2024“…Anterior corneal SIA was significantly correlated to Dis-En and Dis-Ex in the superior CCI group. …”
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20518
Table 5_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx
Published 2025“…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …”
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20519
Data Sheet 6_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for...
Published 2025“…Key risk factors included behavioral and metabolic factors, among which a diet low in whole grains significantly increased CRC incidence.</p>Conclusion<p>From 1990 to 2021, the global CRC burden increased significantly, with notable variations across SDI regions. …”
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20520
Table 2_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx
Published 2025“…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …”