Image_2_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

"…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"

Table 1_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.do... حسب Junhyeok Choi (14078586)

"…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"

Image 2_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

"…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"

Data Sheet 1_Aloe-emodin plus TIENAM ameliorate cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating microbiota.docx حسب Jingqian Su (666622)

"…Combining AE and TIE significantly enhanced survival rates, and reduced inflammation and bacterial load in septic mice, indicating potent antimicrobial properties. …"

Table 1_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

"…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"

Table 4_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.xl... حسب Junhyeok Choi (14078586)

"…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"

Table 4_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

"…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"

Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf حسب Ling Wang (56577)

"…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …"

Data Sheet 1_Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study.pdf حسب Sam Salek (5800727)

"…Background<p>Disease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.…"

Image_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

"…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"

MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway حسب Jing Liu (38537)

"…</p> <p>ATP binding cassette transporter 1 (ABCB1) had the highest mutation frequency and multiple mutation types in HNSCC, and the decreased ABCB1 was significantly related to better prognosis of HNSCC patients. …"

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx حسب Raneen Sawaid Kaiyal (20418824)

"…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…"

Data Sheet 2_Impact of leukemia subtype and demographics on patient quality of life in 76 countries: a cross-sectional study.docx حسب Sam Salek (5800727)

"…Background<p>Disease-specific factors associated with decreased quality of life (QoL) in patients with leukemia have not been studied in a large-scale, global, observational study.…"

Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg حسب Chen Liu (75209)

"…</p>Results<p>The LOX family was significantly upregulated in low-grade gliomas and strongly associated with poor clinical outcomes. …"

Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx حسب Eryun Zhang (20172057)

"…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …"

Image 1_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

"…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff حسب Emmrich Wakeford (21249104)

"…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …"

Data Sheet 1_Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study.d... حسب Peipei Huang (3623933)

"…CSF IL-6 and IL-8 levels were significantly elevated in the RSE group compared to patients without seizures and with controlled seizures, decreasing gradually and independently of serum cytokine levels. …"

Table 1_Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometriti... حسب Xian Chen (107385)

"…After PRP treatment, the proportions of endometrial CD8⁺ T cells, CD56⁺ NK cells, Foxp3⁺ Treg cells, and T-bet⁺ Th1 cells were significantly decreased in patients with persistent CE. …"

Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion حسب Qingbo Lv (21676001)

"…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …"