يعرض 21,201 - 21,220 نتائج من 21,342 نتيجة بحث عن '(( significantly ((lower decrease) OR (linear decrease)) ) OR ( significant decrease decrease ))', وقت الاستعلام: 0.60s تنقيح النتائج
  1. 21201

    Image 6_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... حسب Yun Xu (139234)

    منشور في 2025
    "…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …"
  2. 21202

    Table 7_Polygonatum sibiricum polysaccharides enhance pancreatic β-cell function in diabetic zebrafish by mitigating mitochondrial oxidative damage via the AMPK-SIRT1 pathway.xlsx حسب Fan Lin (625737)

    منشور في 2025
    "…</p>Results<p>Polygonatum sibiricum polysaccharides significantly improved zebrafish swimming behavior, reduced blood glucose and fructosamine levels, and enhanced ATP production (p < 0.01). …"
  3. 21203

    Dataset. حسب Wanjun Zhang (496858)

    منشور في 2025
    "…The results demonstrate that the self-correcting fuzzy PID control significantly optimizes key performance metrics: overshoot (reduced by 21.3%), settling time (shortened by 34.7%), and steady-rate error (decreased by 18.9%), outperforming both traditional PID and fuzzy PID methods in concentration and pH regulation. …"
  4. 21204

    Image 3_The benefits and risks of adding PD-1/PD-L1 inhibitors to chemotherapy for stage IIIb-IV non-small-cell lung cancer: an updated meta-analysis based on phase 3 randomized co... حسب Yun Xu (139234)

    منشور في 2025
    "…The most common AEs in the PC group were blood toxicity related AEs (anemia, neutrophil count decreased, etc).</p>Conclusion<p>The PC therapy continues to provide a substantial survival benefit for patients with stage IIIb-IV NSCLC. …"
  5. 21205

    Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... حسب Khalidah Ibraheem (9525220)

    منشور في 2025
    "…</p>Results<p>Chemotherapy agents reduced keratinocyte viability at 37°C by ∼65%–70%, induced HF dystrophy evident by decreased proliferation (9% Ki-67+ cells), increased apoptosis (23% TUNEL+ cells), and reduced anagen (∼10%) and pigmentation. …"
  6. 21206

    Image_1_Unraveling the key mechanisms of Gastrodia elata continuous cropping obstacles: soil bacteria Massilia, Burkholderia-Caballeronia-Paraburkholderia, and Dyella along with so... حسب Mingzheng Duan (11630632)

    منشور في 2024
    "…However, continuous cropping of this species has led to various obstacles, such as microbial disease and pest infestation, significantly affecting the production and development of valuable medicinal and food resources. …"
  7. 21207

    Figure 1 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia حسب Sydney A. Skupa (18597728)

    منشور في 2025
    "…Asterisks denote the significance between WT B6 and Eμ-TCL1 mice at each time point. …"
  8. 21208

    Dupilumab improves sense of smell and clinical outcomes in patients with severe chronic rhinosinusitis with nasal polyps with anosmia حسب Andrew P. Lane (20367704)

    منشور في 2024
    "…<p>Loss of sense of smell is a cardinal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP) and significantly impacts health-related quality-of-life. …"
  9. 21209

    Additional file 1 of MDM2-amplified esophageal adenocarcinomas exhibit an activated metabolic and immunosuppressive phenotype with multiple potential therapeutic targets حسب Karl Knipper (15016346)

    منشور في 2025
    "…Volcano plot of all detected proteins comparing the proteome of neoadjuvantly treated MDM2-amplified and non-amplified tumors. Grey: not significantly different expressed, blue: significantly decreased expression in neoadjuvantly treated MDM2-amplified tumors, red: significantly increased expression in neoadjuvantly treated MDM2-amplified tumors. …"
  10. 21210

    H2AK119ub is bidirectionally dynamic within cis-regulatory elements during neurodevelopment. حسب Aditya Parmar (22331873)

    منشور في 2025
    "…<b>(B)</b> Volcano plot depicting H2AK119ub abundance, as detected in normalized CUT&RUN data from early and late cerebellum, within SEACR-defined consensus peak regions. The significance threshold was a false-discovery rate <0.05, as defined by DiffBind [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011843#pgen.1011843.ref065" target="_blank">65</a>] (n = 4). …"
  11. 21211

    Table2_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  12. 21212

    Table4_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  13. 21213

    Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. حسب Daniel Sobrido-Cameán (5049743)

    منشور في 2025
    "…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …"
  14. 21214

    Table1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  15. 21215

    DataSheet1_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.pdf حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  16. 21216

    Table5_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  17. 21217

    Table3_Causal relationship between plasma lipidome and four types of pancreatitis: a bidirectional Mendelian randomization study.xlsx حسب Runzhou Ma (19758996)

    منشور في 2024
    "…Furthermore, genetically predicted increased LPC (20:4) (OR = 0.862, 95%CI = 0.796-0.934, P = 3.00 × 10<sup>-4</sup>, PFDR = 0.027) and SM (34:2;O2) (OR = 0.753, 95%CI = 0.659-0.860, P = 2.97 × 10<sup>-5</sup>, PFDR = 0.005) levels were associated with decreased risk of ACP.</p>Conclusions<p>Our findings provide evidence of causal associations between the specific types of lipidome and pancreatitis, offering new insights into future clinical research.…"
  18. 21218
  19. 21219

    Figure 6 from Gut Microbiome Profiling in Eμ-TCL1 Mice Reveals Intestinal Changes and a Dysbiotic Signature Specific to Chronic Lymphocytic Leukemia حسب Sydney A. Skupa (18597728)

    منشور في 2025
    "…Asterisks denote the significance between antibiotic-receiving or water-receiving mice over time (*, <i>P</i> < 0.05). …"
  20. 21220

    Table 1_Widely conserved miRNAs in buffalo milk extracellular vesicles survive gastrointestinal digestion and potentially target neural and immunomodulatory contexts.docx حسب Olubukunmi Amos Ilori (22446976)

    منشور في 2025
    "…The miRNA cargo exhibited a similar pattern, except miR-141-3p, miR-153-3p, both increased slightly, and miR-223-3p, which increased substantially; miR-148a-3p, which decreased; and miR-33a-3p, which was no longer detectable after digestion. …"