Figure 5 from Clinical Validation of a Cell-Free DNA Fragmentome Assay for Augmentation of Lung Cancer Early Detection by Peter J. Mazzone (20018668)

“…Population-level modeling demonstrates significant health benefits when a blood-based test is available as an alternative for lung cancer screening.…”

Data_Sheet_1_Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease.docx by Fahad Mubariz (16010003)

“…Using PD patients’ induced-pluripotent stem cells (iPSCs), we examined TFEB activity and regulation of the ALP in dopaminergic neuronal cultures generated from iPSC lines harboring heterozygous GBA1 mutations and the CRISPR/Cas9-corrected isogenic controls. Our data showed a significant decrease in TFEB transcriptional activity and attenuated expression of many genes in the CLEAR network in GBA1 mutant neurons, but not in the isogenic gene-corrected cells. …”

Table2_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.pdf by Elena Chiappini (304802)

“…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …”

Data Sheet 1_Cervical cancer burden and attributable risk factors across different age and regions from 1990 to 2021 and future burden prediction: results from the global burden of... by Lu-yao Cheng (20687651)

“…Between 1990 and 2021, the global ASDR decreased from 9.68 to 6.62 per 100,000, and the rate of age-standardized DALYs decreased from 330.11 to 226.28 per 100,000. …”

Data Sheet 1_Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis.zip by Xinchang Lun (11996469)

“…By day 28, only SOD expression showed a significant decrease in both parasitism groups.</p>Conclusion<p>This study uncovered the dynamic changes in metabolism and immune responses of striped hamsters parasitized by Xenopsylla cheopis. …”

Supplementary file 1_Therapeutic effects of Balanites aegyptiaca DEL extract on diabetes mellitus: a systematic review.pdf by Olubukola Adebisi Odeniran (22162777)

“…All the studies were appraised for blood glucose levels, and a reduction in blood glucose was reported in all in vivo studies, regardless of the plant part used. Significant decrease in blood glucose level was recorded in Alloxan- and streptozotocin-induced rat/mice diabetes. …”

Table 1_High-dose medium-term HMB supplementation did not trigger body composition changes in trained and untrained males under usual conditions or high-intensity functional exerci... by Krzysztof Durkalec-Michalski (4691311)

“…The intervention had no significant effect on BM, FFM, FM, or TBW. BM, FFM (kg), TBW, and TBW/FFM were higher at SUP+FGB vs. …”

Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx by Stefanie Hoffmann (3756733)

“…Introduction<p>The potential for drug-induced gastrointestinal (GI) toxicity is significant, since the GI tract is one of the first barriers which come in to contact with oral drugs. …”

Data Sheet 1_Impact of the SARS-COV-2 pandemic on access to health services in Angola: a focus on diagnosis and treatment services for tuberculosis.docx by Susanna Caminada (16789893)

“…</p>Results<p>There was a significant decline in access to TB services during the pandemic, with a substantial decrease in reported cases (−15.5% in 2020; −18.3% in 2021) and treatment rate (from 86% in 2019 to 68% in 2020), an increase in multidrug-resistant-TB (from 0.2% in 2018 to 2.1% in 2022) and TB/HIV co-infections (from 6% in 2018 to 8.8% in 2021). …”

Measurements per sample and cycle. by David Nora (10098723)

“…These two variables were measured, and the results correlated with the physical properties of various raw materials, including hardness and grain size. Our results show significant differences in the efficiency between the different types of raw materials. …”

Supplementary information files for "Dietary habits across the primary-secondary school transition: A systematic review" by Africa Peral-Suarez (20773982)

“…The frequency of consuming breakfast, fruit, vegetables, and milk decreased across the primary-secondary school transition. …”

Table 2_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Table 1_DYRK1A roles in human neural progenitors.xlsx by Jeremie Courraud (20871932)

“…In addition, DYRK1A-KD led to a reduction in p21 protein levels, despite an increase in the expression of a minor transcript variant for this gene, and a decrease in ERK pathway activation.</p>Discussion<p>Together, the DYRK1A interactome in hNSCs and the gene expression changes induced by its depletion highlight the significant role of DYRK1A in regulating hNSC proliferation. …”

Survey respondent characteristics by round. by Robert C. Hughes (2726941)

“…In conclusion, despite adaptations over time and the decrease in reported disruptions, prolonged economic shock was associated with multiple adverse effects on Nurturing Care. …”

Table 1_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.xlsx by Ethan C. J. Berry (21074345)

“…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”

Image_2_Widely targeted metabolomics and SPME-GC-MS analysis revealed the quality characteristics of non-volatile/volatile compounds in Zheng’an Bai tea.tif by Li Liu (75607)

“…Moderate spreading is conducive to the release of the aroma of tea leaves, but fixation causes a sharp decrease in the content of most volatile metabolites. …”

Table 6_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Pre-existing peat organic matter remained relatively stable; significant priming of its consumption was not observed, nor was its structural alteration.…”

Table 1_The impact of telework on absenteeism, presenteeism, and return to work among workers with health conditions: a scoping review.docx by Julien Ducas (20501079)

“…In contrast, findings on presenteeism are conflicting: some studies report that telework increases the likelihood of working while sick, others suggest a decrease, and some report no significant impact or conflicting results. …”

Table_1_Abnormal outer and inner retina in a mouse model of Huntington’s disease with age.DOCX by Dashuang Yang (19956078)

“…Pathological assessments of the striatum and evaluations of motor function confirmed significant HD-related alterations in R6/1 mice at 6 months. …”

Table_2_Global burden of drug use disorders by region and country, 1990–2021.docx by Shuyan Zhang (426593)

“…Nationally, the United States of America reported the largest increase in age-standardized DALY rates and EAPC for ASIR (EAPC of 4.88, 1.05, respectively), while South Africa had the most significant decrease in EAPC (EAPC of −3.62, −1.52, respectively). …”