Data Sheet 1_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf by Chutian Zhang (10732350)

“…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…”

Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025 by Alexandre Berthier (16876311)

“…</p><h3>Conclusions</h3><p dir="ltr">Seemingly reversible metabolic challenges in early adulthood may predispose the liver to exacerbated metabolic dysfunctions when confronted with chronic challenges later in life.</p><h3>Impact and implications</h3><p dir="ltr">While the health significance of transient insulin resistance is well established, the molecular processes that occur after such episodes are poorly understood. …”

Data Sheet 1_The association of healthy eating index score and n-3 fatty acid intake with cardiovascular diseases incidence and lipid biomarkers in Alberta’s tomorrow project cohor... by Reihane Taheri (14188808)

“…No significant association was found between absolute n-3 FA intake (g/d) with CVD incidence. …”

DataSheet1_Updated evidence of the Naoshuantong capsule against ischemic stroke: a systematic review and meta-analysis of randomized controlled trials.docx by Cuilin Que (19743256)

“…Background<p>Stroke is a serious health issue that can result in death or disability, leading to a significant economic strain on society and families. …”

Supplementary file 1_An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study.... by Miguel Ángel Robles-Sánchez (21211703)

“…Lifestyle habits remained mostly unchanged, except for medication self-management and diet, whereas visits to nurses and other professionals in MS units significantly decreased. Physical health composite scores in the MS quality of life-54 questionnaire decreased, while the mental health composite scores remained unchanged. …”

Image 1_Innate immune pathway activation to modulate mesenchymal stromal cell (MSC) interactions with synovium and cartilage.jpeg by Peter Linde (22011383)

“…STING-MSC-CM decreased IL-6, IL-8 secretion (p = 0.08) by synoviocytes, decreased IL-8 (p = 0.05) by activated chondrocytes, increased G-CSF (p = 0.01), IL-4 (p = 0.01) and decreased IL-5 (p = 0.01) by activated macrophages. …”

Data Sheet 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.xlsx by Demos Kynigopoulos (12420457)

“…</p>Methods<p>We investigated the effects of two FDA-approved metabolic agents—Alirocumab, a PCSK9 inhibitor that lowers LDL cholesterol, and Gliclazide, a sulfonylurea that enhances insulin secretion—in male 5xFAD mice, a transgenic model of AD. …”

Table 1_Case report: Treatment of severe phorate poisoning.xlsx by Wang Kunlun (21287522)

“…Phoratoxon sulfoxide has the highest concentration of these metabolites, followed by phoratoxon sulfone, phorate sulfone, phorate sulfoxide, and phoratoxon, respectively. HP treatment significantly lowered the serum levels of the toxic metabolites terminology. …”

Supplementary Material for: Supportive care for common conditions in small vulnerable newborns and term infants: the evidence by Jiang L. (4145290)

“…Kangaroo mother care (KMC) significantly reduced SVN’s mortality by discharge. Early erythropoiesis stimulating agent lowered SVN’s risk of receiving blood transfusion. …”

Supplementary file 1_Systemic lipid and glucose modulation differentially affects cognitive function and neuroinflammation in a mouse model of Alzheimer’s disease.docx by Demos Kynigopoulos (12420457)

“…</p>Methods<p>We investigated the effects of two FDA-approved metabolic agents—Alirocumab, a PCSK9 inhibitor that lowers LDL cholesterol, and Gliclazide, a sulfonylurea that enhances insulin secretion—in male 5xFAD mice, a transgenic model of AD. …”

Data Sheet 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.docx by Lillia A. Baird (10575941)

“…</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”

Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”

Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…</p>Results<p>Low-dose, but not high-dose, tofacitinib significantly increased survival and delayed weight loss. …”

Data Sheet 1_Allicin ameliorates acute myocardial infarction in rats by modulating calcium homeostasis in cardiomyocytes through the induction of hydrogen sulfide production.docx by Weiyu Liu (3879487)

“…</p>Results<p>The results indicate that allicin significantly enhanced cardiac function, raised H₂S levels in myocardial tissue and serum, reduced necrosis tissue size, decreased myocardial enzyme levels, and improved myocardial pathological changes. …”

Autophagy induced by mechanical stress sensitizes cells to ferroptosis by NCOA4-FTH1 axis by Chenyu Luo (12443535)

“…Whereas the extracellular matrix of tumors provides mechanical cues influencing tumor initiation and progression, its impact on ferroptosis and its mechanisms remains largely unexplored. …”

Data Sheet 1_Speaker-story mapping as a method to evaluate audiovisual scene analysis in a virtual classroom scenario.pdf by Stephan Fremerey (21515144)

“…Results indicate that the experimental condition significantly influenced task performance, mental load, and user behavior but did not affect perceived simulator sickness and presence. …”

Image 1_COP1 drives renal cell carcinoma progression by targeting ACSL4 for ubiquitin-mediated degradation and inhibiting ferroptosis.tif by Yuxiao Zheng (8334027)

“…</p>Results<p>COP1 was significantly correlated with poor patient prognosis. …”

Table 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.xlsx by Jing Wang (6206297)

“…Additionally, tissue chips containing regional liver cancer specimens were used to confirm ACTR6 expression and the clinical impact of prognosis using an immunohistochemistry (IHC) test. …”

Data Sheet 1_Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.do... by Ning Yang (114965)

“…Notably, the EMT-suppressing effect of mZJP was significantly attenuated upon Nrf2 silencing, as evidenced by enhanced cell migration, decreased epithelial marker expression (E-cadherin), increased mesenchymal marker expression (vimentin and α-SMA), suppression of the Nrf2 pathway, and activation of the Akt/GSK3β pathway.…”

Data Sheet 1_Tcirg1 deficiency delays osteoarthritis progression by impairing lysosome acidification and peripheral accumulation in osteoclasts.docx by Rui Sun (177521)

“…This study aims to assess the impact of Tcirg1 on OA progression and to explore its therapeutic potential for the disease treatment.…”