Data Sheet 1_Active layer and permafrost microbial community coalescence increases soil activity and diversity in mixed communities compared to permafrost alone.docx by Stacey J. Doherty (6629561)

“…Microbial communities undergo significant compositional and functional shifts as permafrost thaws. …”

Image 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …”

Data Sheet 1_Comprehensive analysis on the regulatory mechanism of active ingredient accumulation during fermentation process of Massa Medicata Fermentata: microbe and metabolic pr... by Yun Li (692280)

“…Background<p>Massa Medicata Fermentata (MMF) is a traditional medicinal/edible fermented product; however, comprehensive research on the fermentation process from a microscopic perspective remains limited. In this study, we aimed to investigate the dynamic changes and correlations of physicochemical properties, microbial communities, and metabolite profiles in different fermentation stages (0, 48, 72, and 96 h) of MMF.…”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 2_The global, regional, and national alcohol-related colorectal cancer burden and forecasted trends: results from the global burden of disease study 2021.csv by Jinfeng Yao (2200615)

“…In order to mitigate harm, we need to strengthen disease surveillance, early prevention, timely detection, and improved treatment measures, with different approaches and responses for different regions.…”

Table 2_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …”

Supplementary file 1_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”

Supplementary file 4_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”

Divergent Oncogenic Signaling and Immune Microenvironment Changes in Low-Grade Serous Ovarian Cancer Undergoing Intraperitoneal Treatment by Isaac Bishara (21157583)

“…The non-responder demonstrated significant upregulation in proliferation-associated pathways (E2F, MYC targets, G2/M checkpoint), KRAS signaling, epithelial-mesenchymal transition, and unfolded protein response (UPR), correlating with aggressive tumor growth and treatment resistance. …”

An improved <i>in vitro</i> 3T3-L1 adipocyte model of inflammation and insulin resistance by Ifeoluwa A. Odeniyi (19862796)

“…Importantly, insulin resistance and inflammation were still induced in the 12 h treated adipocytes: the expression of the insulin sensitive and inflammatory genes was decreased and increased, respectively. In 72 h treated adipocytes, no significant differences were found in the viability, glucose uptake or insulin-sensitive and inflammatory gene expression. …”

Data Sheet 1_Food and mood: how clean eating content on social media influences affect and body satisfaction in women.docx by Giulia Cossu (3837568)

“…</p>Results<p>There was no significant profile × time interaction effect for positive affect, however it decreased over time (_p² = 0.21). …”

Image 4_The global, regional, and national alcohol-related colorectal cancer burden and forecasted trends: results from the global burden of disease study 2021.tif by Jinfeng Yao (2200615)

“…In order to mitigate harm, we need to strengthen disease surveillance, early prevention, timely detection, and improved treatment measures, with different approaches and responses for different regions.…”

Table 1_Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey.docx by Andreas Czaplicki (21978866)

“…Respondents with only one vaccination reported the highest rate of PCVS symptoms (20.8%), which decreased to 8.9% for those with four or more vaccinations. …”

Table 8_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx by Jiahao Zhou (11385383)

“…Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…”

Table 3_The global, regional, and national alcohol-related colorectal cancer burden and forecasted trends: results from the global burden of disease study 2021.docx by Jinfeng Yao (2200615)

“…In order to mitigate harm, we need to strengthen disease surveillance, early prevention, timely detection, and improved treatment measures, with different approaches and responses for different regions.…”

Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Data Sheet 1_Sleep is enhanced in aged male mice that overexpress calcium/calmodulin-dependent protein kinase IV.docx by Sierra P. Feeney (21466928)

“…Using 2- to 4-month-old (young adult) and 22- to 24-month-old (aged) male and female CaMKIV-overexpressing (CaMKIV-OE) mice, we observed that overexpression of CaMKIV in the forebrain decreased wakefulness and increased the amount of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep in aged male mice, but not young adult male mice, in comparison to age- and sex-matched controls. …”

Supplementary file 2_Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.xlsx by Jinming Cao (7837883)

“…Nationally, the burden of the disease in 2021 is particularly significant in countries such as Mauritius and Italy. …”

Supplementary file 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.docx by Xiaofang Guo (385478)

“…Contrary, the age-standardized DALY rate (ASDR) decreased in idiopathic epilepsy and multiple sclerosis. …”

Table 4_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden... by Jiaoli Xu (20871584)

“…</p>Methods<p>This study utilized the Global Burden of Disease (GBD) database to examine trends in CHD-related mortality among children aged 0-14 from 1990 to 2021.</p>Results<p>We report a 55.34% reduction in CHD-related deaths among children, with global mortality rates decreasing from 28.63 per 100,000 in 1990 to 11.06 per 100,000 in 2021. …”