Details of the GWAS data in this study. by Jing Wang (6206297)

“…The effect of anti-H. pylori IgG seropositivity on CHD may be related to a higher peak insulin response or lower total free cholesterol levels and a decrease in waist circumference and waist-to-hip ratio. …”

Data for Fig 6D. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Data for Fig 5D. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Data for Figs 8A–8H, 9A–9K, 10A–10I. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”

Active DNA Demethylation Mediated by <i>OsGADD45a2</i> Regulates Growth, Development, and Blast (Magnaporthe oryzea) Resistance in Rice by Ganghua Zhou (9283406)

“…In <i>OsGADD45a2</i> overexpression lines, significant decreases in CG and CHG methylation levels were observed in protein-coding genes, leading to their upregulation. …”

COVID-19 in Lebanon: The daily number of COVID-19 cases throughout the waves of the pandemic in Lebanon and associated SARS-CoV-2 variants between January 2021 and September 2022. by Rima Moghnieh (679199)

Demographic characteristics of participants. by Evelyn Aboagye Addae (22648064)

“…While there was a significant direct negative effect of fear of COVID-19 on SWB in the absence of the mediators, there was no significant negative effect of fear of COVID-19 on SWB after adjusting for the mediators in the model. …”

Participant characteristics and study measures. by Evelyn Aboagye Addae (22648064)

“…While there was a significant direct negative effect of fear of COVID-19 on SWB in the absence of the mediators, there was no significant negative effect of fear of COVID-19 on SWB after adjusting for the mediators in the model. …”

Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx by Yan Li (23143)

“…Background<p>Limited research is available on the associations between healthy lifestyles and age-related diseases, particularly those involving multiple diseases and their underlying mechanisms. We aimed to determine whether healthy lifestyles are associated with a lower likelihood of age-related diseases, and whether metabolites mediate these associations.…”

Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx by Yan Li (23143)

“…Background<p>Limited research is available on the associations between healthy lifestyles and age-related diseases, particularly those involving multiple diseases and their underlying mechanisms. We aimed to determine whether healthy lifestyles are associated with a lower likelihood of age-related diseases, and whether metabolites mediate these associations.…”

Flow chart of research object screening. by Wenyao Xie (21567889)

“…</p><p>Results</p><p>Cancer patients had higher mean age (68.70 ± 11.85 vs. 48.36 ± 17.00 years), lower testosterone levels (377.35 ± 204.26 vs. 415.02 ± 183.92 ng/dL, P < 0.001), and lower ALI values (64.86 ± 118.61 vs. 72.68 ± 185.25, P = 0.053) than non-cancer controls. …”

Table 1_Cross-education: motor unit adaptations mediate the strength increase in non-trained muscles following 8 weeks of unilateral resistance training.xlsx by Edoardo Lecce (20518145)

Data from: The relationship between pollinator community and pollination services is mediated by floral abundance in urban landscapes by Hamutahl Cohen (11520447)

“…In the greenhouse, we found that jalapeño fruit weight and seed number was significantly greater with insect-mediated pollination than without. …”

CRISPR/Cas9-mediated editing of barley lipoxygenase genes promotes grain fatty acid accumulation and storability by Zhanghui Zeng (3571331)

“…Transgene-free homozygous barley mutants of <i>loxB</i>, <i>loxC1</i>, and <i>loxAloxC1</i> were generated using CRISPR/Cas9-mediated genome editing. Compared to the wild-type, all mutants displayed normal plant height, tiller number, and grain size, although the <i>loxC1</i> and <i>loxAloxC1</i> mutants exhibited significantly lower thousand grain weights. …”

Data Sheet 1_Association of the dietary index for gut microbiota with sleep disorder among US adults: the mediation effect of dietary inflammation index.docx by Yingying Li (50341)

“…A higher DI-GM score is associated with a lower incidence of sleep disorders, while the DII significantly mediated the relationship between DI-GM and sleep disorders. …”

Table 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx by Xiongbao Wang (12508462)

<i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation by jin guan (21792620)

“…Typhimurium, among which the <i>StiP</i> deletion strain (263<i>ΔStiP</i>) showed the greatest serum resistance reduction (2.49-fold). We further explored the role of <i>StiP</i> in host blood environment adaptation and found that 263<i>ΔStiP</i> displayed 3.12-fold reduced HeLa cell adhesion, 3.74-fold lower HeLa cell invasion, 1.92-fold decreased intra-macrophage survival, and 50% reduced serum resistance versus wild-type 263 (WT263), collectively indicating that <i>StiP</i> is critical for host blood environment adaptation in invasive <i>S</i>. …”

Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... by Holger Neb (13018218)

“…</p>Methods and study design<p>Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we determined the levels of 53 lipid mediators in plasma from nine patients. …”

Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... by Holger Neb (13018218)

“…</p>Methods and study design<p>Using liquid chromatography-tandem mass spectrometry (LC-MS/MS), we determined the levels of 53 lipid mediators in plasma from nine patients. …”