Evogliptin attenuates the phenotypic switch of VSMCs during CER treatment by decreasing the osteogenesis-associated genes <i>in-vitro.</i> by Razia Rashid Rahil (22772495)

Conditional ablation of <i>Ybx1</i> leads to a reduction in cortical progenitor cell pool and a decrease in cortical thickness. by Jian Zhang (1682)

Male flies with a mixed background have not responded to high temperature-mediated body fat loss. by Tucker Hopkins (20790529)

Evogliptin attenuates the pyroptotic cell death of VSMCs during CER treatment by decreasing the pyroptotic-associated genes and GSDM-D cleavage efficiency <i>in-vitro.</i> by Razia Rashid Rahil (22772495)

Inhibition of LDHA leads to decreased ATP, reduced AKT phosphorylation, and enhanced chemotherapy sensitivity to LBP in A549 and NCL-H1975 cells. by Siyu Yuan (7425719)

The constitutively active form of insulin receptor and knockdown of FoxO block high temperature-mediated body fat loss. by Tucker Hopkins (20790529)

Results of two-way ANCOVA for <i>InR</i> and <i>Thor</i> expression differences by temperature and nutritional state interaction with <i>FoxO</i> as a covariate. by Tucker Hopkins (20790529)

High ambient temperatures reduce body fat and alter the expression of genes involved in lipid metabolism. by Tucker Hopkins (20790529)

Primer sequences for qPCR. by Tucker Hopkins (20790529)

“…Furthermore, when S2R + <i>Drosophila</i> cells are incubated at high temperatures, there is a marked decrease in Akt phosphorylation, directly supporting the notion that elevated temperatures can inhibit insulin signaling in a cell-autonomous manner, independent of Ilp levels. …”

Source data for graphs. by Tucker Hopkins (20790529)

“…Furthermore, when S2R + <i>Drosophila</i> cells are incubated at high temperatures, there is a marked decrease in Akt phosphorylation, directly supporting the notion that elevated temperatures can inhibit insulin signaling in a cell-autonomous manner, independent of Ilp levels. …”

The reagents used in this study. by Tucker Hopkins (20790529)

“…Furthermore, when S2R + <i>Drosophila</i> cells are incubated at high temperatures, there is a marked decrease in Akt phosphorylation, directly supporting the notion that elevated temperatures can inhibit insulin signaling in a cell-autonomous manner, independent of Ilp levels. …”

Densities of pAkt/tAkt bands from Western blots were quantified. by Tucker Hopkins (20790529)

High temperatures regulate the insulin signaling pathway. by Tucker Hopkins (20790529)

Results of one-way ANOVA for <i>Thor</i> expression differences by temperature and nutritional state combination. by Tucker Hopkins (20790529)

Results of one-way ANOVA for body fat differences by temperature and sex combination. by Tucker Hopkins (20790529)

Results of one-way ANOVA for <i>FoxO</i> expression differences by temperature and nutritional state combination. by Tucker Hopkins (20790529)

Results of one-way ANOVA for <i>InR</i> expression differences by temperature and nutritional state combination. by Tucker Hopkins (20790529)

Eggs jointly coordinate a caspase-1 and caspase-8 dependent pyroptotic cell death. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

related to Fig 5. (A) the total number of eggs in the livers did not differ between BL/6 and Gsdmd-/- mice. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)

related to Fig 3. (A) Live eggs induce AIM2 pyroptosome formation. Microscopy of AIM2-citrine macrophages stimulated with live eggs for 48 h. by Madhusoodhanan Suresh Kumar Meena Kumari (20896666)