Image 2_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…</p>Core tip<p>The aim of this study was to assess the association of Hemoglobin Glycation Index(HGI) with all-cause mortality in non-type 2 diabetic patients based on a 10-year cohort study from China. After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Image 1_Hemoglobin glycation index and all-cause mortality in adults: insights from a decade-long prospective cohort study.tif by Yue-Yang Zhang (14258160)

“…</p>Core tip<p>The aim of this study was to assess the association of Hemoglobin Glycation Index(HGI) with all-cause mortality in non-type 2 diabetic patients based on a 10-year cohort study from China. After COX regression, restricted cubic spline analysis, and subgroup analyses, it was found that a significant increase or decrease in HGI adversely affected long-term survival.…”

Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip by Yunsheng Zhang (474242)

“…Background<p>Traumatic brain injury (TBI) triggers a cascade of neuroinflammatory responses mediated by microglial activation, which significantly contributes to secondary brain damage. …”

Identification of a Novel Virulence Factor in <i>Klebsiella pneumoniae</i> through CpxR-Dependent Transcriptional Activation by Runze Wang (21792959)

“…Among the genes exhibiting significantly decreased expression upon <i>cpxR</i> deletion<i>, </i>we identified a novel potential virulence factor KPHS_28080. …”

Table 1_Effects of different reduction patterns on stress distribution in patients with intertrochanteric fractures with intramedullary nail fixation: a finite element analysis.xls... by Jiajing Zhu (5117738)

“…</p>Results<p>As the head–neck fragment moved forward, the von Mises stress at the fracture surface, the proximal intersection point of the intramedullary nail, and the distal intersection point gradually decreased. This resulted in reduced fracture displacement, a significant decrease in trabecular bone volume, and a slight increase in the risk of screw cut-out. …”

Data Sheet 1_Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.zip by Dongsheng Wu (2469307)

“…</p>Results<p>The randomized controlled trials (RCTs) included in this review examined dietary supplementation with eight polyphenols—curcumin, resveratrol, anthocyanins, quercetin, salidroside, dietary beetroot juice, pomegranate juice, and adjunctive oral AKL1 treatment—across a total of 894 participants. This systematic review and meta-analysis revealed that, compared to a placebo; ① Curcumin significantly reduced systolic blood pressure (SBP) and improved FEV1(SMD=-0.82, 95%CI -1.53 to -0.11); ② Salidroside was effective in reducing thrombotic markers (TT, D-D), inflammatory factors (TNF-α) and symptom scores (CAT) (p<0.01); ③ Resveratrol significantly downregulates serum TNF-α and IL-8 levels (p=0.003); ④ Anthocyanins may accelerate lung function decline (decreased FEV1/FVC, which needs to be interpreted with caution); ⑤ Other polyphenols (quercetin, pomegranate juice, AKL1, etc.) did not show significant efficacy or insufficient evidence. …”

Data Sheet 1_Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study.pdf by Rebecca Lyng Holm (20620406)

“…There was no statistically significant effect of exercise on insulin concentration, but a tendency of reduced concentrations 4 h after HIIT (p = 0.093). …”

Supplementary file 1_The action of ginsenoside Rg1 in patients with carotid atherosclerosis: a controlled clinical trial.docx by Xu Fang (450501)

“…Group 3 received the same treatment as Group 2, but with Bayaspirin replaced by ginsenoside Rg1 (n = 41). This study adopted a single-blind design: by uniformly encapsulating the tablets in their original form in blind bags, the subjects took them at regular intervals and in fixed quantities There were no significant differences in baseline characteristics among the groups before treatment (P > 0.05). …”

Data Sheet 1_Understanding mechanistic relationships between IgG titers and Fc effector functions: a computational framework to assess polyfunctionality.docx by Suzanne K. Shoffner-Beck (22253548)

“…Surprisingly, simulated boosting of IgG3 alone had the potential to significantly decrease ADCP (p<0.00001), though it would increase ADCC responses. …”

Supplementary file 1_Clinical utility of the PBAC score in quantifying treatment response to hysteroscopy: a retrospective observational study.docx by Ömer Faruk Öz (22702202)

“…Data were analyzed using SPSS version 26, and p < 0.05 was considered statistically significant.</p>Results<p>Of the 327 patients included in the study, 91.1% had a baseline PBAC score ≥100, which significantly decreased following hysteroscopy (mean reduction: 393 points; p < .001). …”

Table 3_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.docx by Ethan C. J. Berry (21074345)

“…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”

Table 1_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.xlsx by Ethan C. J. Berry (21074345)

“…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”

DataSheet1_Kinetics of endothelin-1 and effect selective ETA antagonism on ETB activation: a mathematical modeling analysis.docx by K. Melissa Hallow (9248960)

“…The drug concentration required to cause a decrease in [ET1-ET_B] was lower as ET_A selectivity decreased.…”

Table 2_A scoping review of the feasibility, usability, and efficacy of digital interventions in older adults concerning physical activity and/or exercise.docx by Ethan C. J. Berry (21074345)

“…Background:<p>The global population is aging, leading to significant health challenges among older adults, such as reduced muscle mass, increased risks of dementias, and chronic diseases. …”

Data Sheet 1_Perceived protective behavioral changes in Chinese residents post-dynamic zero-COVID policy lifting: a cross-sectional study.docx by Yuan-Yuan Song (6287387)

“…Avoiding dining out or gathering with friends had the highest percentage of individuals reporting an increase (71.3%), whereas maintaining a social distance of more than 1 m had the highest percentage of individuals reporting a decrease (17.5%). …”

Table 1_Rainfall distribution variability controls surface but not belowground litter decomposition in a semi-arid shrubland.docx by Yulin Li (36434)

“…</p>Results<p>Decomposition of belowground litter was consistently higher than that of surface litter over the entire field-incubation process. Mass loss significantly decreased in surface litter but not in belowground litter due to the lower frequency and larger amount of precipitation compared to the control treatment. …”

Table 1_Association of brain-derived neurotrophic factor levels at different trimesters and new-onset depressive symptom in the third trimester among pregnant women: a longitudinal... by Yue-rong Zhang (21838784)

“…Each 1 pg/mL increase of first trimester BDNF was associated with a 43% decrease in the risk of prenatal depressive symptoms (95% confidence interval [95% CI]: 0.51, 0.65); each 1 pg/mL increase of second trimester BDNF was a 39% decrease in the risk of prenatal depressive symptoms (95% CI: 0.54, 0.68); each 1 pg/mL increase of third trimester BDNF was associated with a 36% decrease in the risk of prenatal depressive symptoms (95% CI: 0.58, 0.71).…”

Supplementary file 2_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx by Yi-Chang Zhao (14080107)

“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”

Supplementary file 5_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx by Yi-Chang Zhao (14080107)

“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”

Supplementary file 3_Practical utility of meropenem therapeutic drug monitoring: a systematic review of evidence for clinical application.docx by Yi-Chang Zhao (14080107)

“…CRP levels decreased significantly (mean difference = 14.91; 95% CI: 2.79–27.02), while changes in PCT, WBC, and neutrophil ratios were non-significant. …”