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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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12281
Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx
Published 2025“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”
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12282
Table 1_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx
Published 2025“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”
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12283
Table 1_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.docx
Published 2025“…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …”
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12284
Table 2_Improvement of irritable bowel syndrome with glucagon like peptide-1 receptor agonists: a systematic review and meta-analysis.xlsx
Published 2025“…</p>Results<p>The study found that ROSE-010 (100 µg) significantly lowered pain intensity in IBS patients compared to a placebo, with an overall odds ratio of 2.30, 95% CI: 1.53-3.46. …”
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12285
Comparison of the effectiveness of Models 1, 2a and 2b in estimating fetal fraction (FF) based on telomere content.
Published 2025“…The RMSE decreased to 0.0216 for the <i>seqFF</i> model and 0.0190 for the <i>comboFF</i> model, indicating a strong predictive improvement. …”
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12286
Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx
Published 2025“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”
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12287
Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx
Published 2025“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”
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12288
Table 1_Association between telomere length and idiopathic normal pressure hydrocephalus: a Mendelian randomization study.docx
Published 2024“…</p>Results<p>Genetically determined longer telomere length was significantly associated with decreased risk of iNPH (OR = 0.44, 95% CI 0.24–0.80; p = 0.008). …”
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12289
Table 1_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…Subsequently, we discovered that DASH levels are significantly negatively correlated with waist circumference (WC), fasting plasma glucose (FPG), triglycerides (TG), and systolic blood pressure (SBP), while exhibiting a positive correlation with high-density lipoprotein cholesterol (HDL-C) through RCS curves and linear regression.…”
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12290
Table 2_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx
Published 2025“…Subsequently, we discovered that DASH levels are significantly negatively correlated with waist circumference (WC), fasting plasma glucose (FPG), triglycerides (TG), and systolic blood pressure (SBP), while exhibiting a positive correlation with high-density lipoprotein cholesterol (HDL-C) through RCS curves and linear regression.…”
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12291
ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer
Published 2025“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease, marked by a survival rate of only 12%. …”
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12292
Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders
Published 2025“…We have developed a potent GPR119 agonist, MKP10241, which has elevated cyclic adenosine monophosphate (cAMP) levels in the GPR119 expressing cell line and reduced blood glucose levels and HbA1c in acute models and a chronic diabetic mouse model. …”
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12293
Data Sheet 1_Phyllotaxy and environmental factors influences on leaf trait dimensions in Fraxinus mandshurica: a multidimensional approach within temperate forests.docx
Published 2025“…</p>Results<p>We found that (1) specific leaf area and leaf nitrogen concentration significantly increase along the phyllotaxy gradient (from phyllotaxy 1 to 6), while leaf dry matter content, leaf thickness, and stomatal density significantly decrease. …”
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12294
Data Sheet 2_Forecasting the production and export of shrimp in Bangladesh: a policy focused time series analysis.docx
Published 2025“…The VAR(1) model predicts a slight decline in production by 2026–27, with exports potentially decreasing by a factor of 3.2 compared to 2010–11. …”
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12295
Data Sheet 1_Forecasting the production and export of shrimp in Bangladesh: a policy focused time series analysis.docx
Published 2025“…The VAR(1) model predicts a slight decline in production by 2026–27, with exports potentially decreasing by a factor of 3.2 compared to 2010–11. …”
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12296
Data Sheet 1_A distal regulatory element regulates Wx gene expression and the amylose content in rice.pdf
Published 2025“…However, no significant difference in amylose content was observed between wild-type plants and Wx<sup>a</sup>-cre mutants which carried the Wx<sup>a</sup> allele. …”
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12297
Data Sheet 1_The effects of sleep deprivation on cognitive flexibility: a scoping review of outcomes and biological mechanisms.docx
Published 2025“…Background<p>Sleep is vital for physical and mental health, yet sleep deprivation is a widespread issue that may impair cognitive flexibility, leading to rigid thinking and slower decision-making. …”
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12298
Table 1_Assessment the relationship between health anxiety and iranian nurses’ quality of life: a cross-sectional study.docx
Published 2025“…</p>Conclusion<p>This study showed that there is a significant relationship between health anxiety and different dimensions of quality of life, so that the quality of life of nurses decreases with the increase of health anxiety.…”
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12299
Cell-targeted transgenic control of 5HT<sub>2A</sub>R levels in neurons and glia during the experience-dependent critical period.
Published 2024“…Two-way ANOVA with Tukey’s multiple comparison shows EB experience-dependent increase in 5HT<sub>2A</sub> receptor levels in both transgenic controls (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 5.38 × 10<sup>−10</sup>, <i>elav</i>-Gal4; <i>p</i> = 0.0205), a significant decrease in 5HT<sub>2A</sub> receptor levels in both RNAi conditions (<i>n</i> = 10 each, <i>repo-</i>Gal4<i>; p</i> = 4.63 × 10<sup>−10</sup>, <i>elav-</i>Gal4; <i>p</i> = 1.05 × 10<sup>−9</sup>), and a significant elevated EB response with glial <i>5HT</i><sub><i>2A</i></sub><i>R</i> OE (<i>n</i> = 10/condition, <i>p</i> = 2.36 × 10<sup>−9</sup>). …”
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12300
Data Sheet 2_Effectiveness and safety of acupuncture and related therapies for pediatric asthma: a systematic review and meta-analysis.docx
Published 2025“…It has significantly increased serum immunoglobulin A (IgA) levels [MD = 0.31, 95% CI (0.22, 0.41), p < 0.0001]. …”