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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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18041
Supplementary file 5_Protective and risk factors in daily life associated with cognitive decline of older adults.docx
Published 2025“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.…”
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18042
Supplementary file 3_Protective and risk factors in daily life associated with cognitive decline of older adults.docx
Published 2025“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.…”
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18043
Supplementary file 2_Protective and risk factors in daily life associated with cognitive decline of older adults.docx
Published 2025“…Then a predictive model using logistic regression was established based on the most significant protective and risk factors.…”
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18044
date-Guo.xlsx
Published 2025“…We found that the N enrichment significantly decreased the species diversity of seed rain, seed bank, and seedling, ultimately resulting in the loss of plant diversity. …”
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18045
Table 1_RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae.docx
Published 2024“…We found that the ΔrfaH mutant led to a significantly decreased mortality of K. pneumoniae in a mouse intraperitoneal infection model. …”
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18046
Data Sheet 1_CD46 TREM1 regulates the autophagy marker LC3B ATG5 in oral squamous cell carcinoma.docx
Published 2025“…In vivo experiments showed that the tumor volume of the shRNA group was significantly smaller than that of the SC-shRNA group (P<0.01), the expression of CD46 and TREM1 was decreased considerably, and the expression of LC3B and ATG5 was higher (P<0.01). …”
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18047
Data Sheet 1_Pseudomonas oryzihabitans D1-104/3 and P. gessardii C31-106/3 differentially modulate the antioxidative response of duckweed (Lemna minor L.) to salt stress.docx
Published 2024“…The doubling time of duckweeds inoculated with P. gessardii C31-106/3 was significantly longer. Additionally, at 0 and 10 mM NaCl, this strain decreased chlorosis in duckweeds. …”
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18048
Differences between outcomes and types of learning during the lockdown and after the pandemic.
Published 2024“…<p>The figure reflects a general trend of decreased frequency in various learning activities after the pandemic compared to during the lockdown, except for reproductive verbal, constructive procedural, and cooperative activities, where there was a significant increase.…”
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18049
DataSheet_1_FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.docx
Published 2024“…Treatment with intravenous immunoglobulin (IVIg) significantly decreases the risk of CAA, possibly through competitive binding to Fc-gamma receptors (FcγRs), which reduces the binding of pathological immune complexes. …”
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18050
Robust chain-length specific reductions in some intermediate chain and long chain PE phospholipids in peroxisomal mutant brain.
Published 2025“…<p><b>A.</b> Levels in mol% of PE 33:3 in <i>pex2</i> and <i>pex16</i> mutant brains show significant decreases in <i>pex</i> mutant brains. …”
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18051
Table1_Carex parva and Carex scabrirostris adopt diverse response strategies to adapt to low-light conditions.docx
Published 2024“…Introduction<p>In recent years, the visible light intensity of lawns has significantly decreased due to obstructions caused by urban shading objects. …”
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18052
Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff
Published 2025“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”
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18053
Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion
Published 2025“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”
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18054
Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff
Published 2025“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”
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18055
Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx
Published 2025“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”
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18056
Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx
Published 2025“…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…”
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18057
Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites
Published 2025“…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …”
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18058
Impact of acute binge-like ethanol exposure during the third-trimester equivalent on subicular interneurons in mice
Published 2025“…Ethanol exposure decreased instantaneous frequency evoked by 250–400 pA current injection in fast-spiking GABAergic interneurons only in female mice (250: <i>p</i> = .019, g = −1.08; 300–450: <i>p</i> = .038, g = −1.06 to- 1.18) but did not significantly affect spontaneous inhibitory postsynaptic currents (sIPSCs) evoked by interneuronal GABA release onto pyramidal neurons.…”
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18059
Lesioning silent neurons reveals functional role.
Published 2025“…Mixed-selective neurons, however, lead to a decreased accuracy when lesioned.</p> <p>(TIFF)</p>…”
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18060
Raw images.
Published 2025“…PPD, Rg1, Rb2, and Rg3 inhibited lipid accumulation in PA-treated HepG2 cells. PA significantly decreased lipid levels in HepG2 cells, which was prevented by PPD, Rg1, Rb2, and Rg3. …”