Image2_Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.JPEG by Liyuan Yu (5341841)

“…GXST and WM combination was significantly more effective than WM alone across several metrics: clinical efficacy rate (odds ratio [OR] = 4.05, 95% confidence interval [CI] = 3.42–4.80), electrocardiogram improvement (OR = 3.39, 95% CI = 2.35–4.87), enhancement in left ventricular ejection fraction (mean difference [MD] = 1.07, 95% CI = 0.69–1.46), reduction in total cholesterol levels (MD = −0.78, 95% CI = −1.20 to −0.35), decrease in tumor necrosis factor-alpha (MD = −1.36, 95% CI = −2.18 to −0.53), and improvement in Chinese medicine evidence score (OR = 3.77, 95% CI = 2.20–6.43). …”

Table1_Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.DOC by Liyuan Yu (5341841)

“…GXST and WM combination was significantly more effective than WM alone across several metrics: clinical efficacy rate (odds ratio [OR] = 4.05, 95% confidence interval [CI] = 3.42–4.80), electrocardiogram improvement (OR = 3.39, 95% CI = 2.35–4.87), enhancement in left ventricular ejection fraction (mean difference [MD] = 1.07, 95% CI = 0.69–1.46), reduction in total cholesterol levels (MD = −0.78, 95% CI = −1.20 to −0.35), decrease in tumor necrosis factor-alpha (MD = −1.36, 95% CI = −2.18 to −0.53), and improvement in Chinese medicine evidence score (OR = 3.77, 95% CI = 2.20–6.43). …”

Image3_Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.JPEG by Liyuan Yu (5341841)

“…GXST and WM combination was significantly more effective than WM alone across several metrics: clinical efficacy rate (odds ratio [OR] = 4.05, 95% confidence interval [CI] = 3.42–4.80), electrocardiogram improvement (OR = 3.39, 95% CI = 2.35–4.87), enhancement in left ventricular ejection fraction (mean difference [MD] = 1.07, 95% CI = 0.69–1.46), reduction in total cholesterol levels (MD = −0.78, 95% CI = −1.20 to −0.35), decrease in tumor necrosis factor-alpha (MD = −1.36, 95% CI = −2.18 to −0.53), and improvement in Chinese medicine evidence score (OR = 3.77, 95% CI = 2.20–6.43). …”

Table2_Efficacy and safety of guanxinshutong capsule combined with western medicine on stable angina pectoris: a systematic review and meta-analysis.DOC by Liyuan Yu (5341841)

“…GXST and WM combination was significantly more effective than WM alone across several metrics: clinical efficacy rate (odds ratio [OR] = 4.05, 95% confidence interval [CI] = 3.42–4.80), electrocardiogram improvement (OR = 3.39, 95% CI = 2.35–4.87), enhancement in left ventricular ejection fraction (mean difference [MD] = 1.07, 95% CI = 0.69–1.46), reduction in total cholesterol levels (MD = −0.78, 95% CI = −1.20 to −0.35), decrease in tumor necrosis factor-alpha (MD = −1.36, 95% CI = −2.18 to −0.53), and improvement in Chinese medicine evidence score (OR = 3.77, 95% CI = 2.20–6.43). …”

β-NAD increases intracellular cAMP concentration via soluble adenylyl cyclase, but this pathway is not essential for the relaxing effect. by Innokentij Jurastow (22430601)

“…<p>(A, B) Recording of intracellular cAMP concentration in HBSMC via FRET, with low FRET ratio indicating high cAMP concentration. β-NAD and isoproterenol cause a decrease in FRET ratio, reflecting rise in intracellular cAMP concentration. …”

DataSheet1_Exploring the effects of moxibustion on cognitive function in rats with multiple cerebral infarctions from the perspective of glial vascular unit repairing.DOCX by Jingji Wang (19925733)

“…Notably, levels of glial fibrillary acidic protein (GFAP) and complement component 3 significantly increased, but those of Connexin43 (CX43) and platelet derived growth factor receptor β (PDGFRβ) significantly decreased in the hippocampus of the rats receiving MMI. …”

Data Sheet 1_An oral M-cell targeted Lactococcus lactis vaccine against Echinococcus multilocularis infection.pdf by Yang Xiao (146335)

“…For both primary and secondary infections, oral immunization with LL-plSAM-GILE led to a significant decrease in the diameter and weight of hepatic cysts.…”

Development and characterization of a bivalent mRNA vaccine targeting the Delta and Omicron variants of SARS-CoV-2 by Xiao-Chuan Xiong (22337097)

“…<p>The emergence of the Omicron variant of SARS-CoV-2 has led to a decrease in vaccine efficacy and contributed to the ongoing epidemic of COVID-19. …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Introduction<p>Sarcopenia, an age-related disorder marked by decreased skeletal muscle mass, strength, and function, is associated with negative health impacts in individuals and financial burdens on families and society. …”

EPB-113 binds to hexameric nsp15 protein. by Benjamin Van Loy (9496075)

“…<p>(A) Thermal shift assay showing the decrease in T_m when 6 µM of nsp15 protein was incubated with 100 µM EPB-113. …”

eIF3d1 phosphorylation but not cap-binding is required for CySC self-renewal. by Ruoxu Wang (9312306)

“…(<b>B</b>) Number of Zfh1⁺ Eya⁻ CySCs in testes in which wild-type (eIF3d1^WT), phospho-mimetic (eIF3d1^DD) or phospho-dead (eIF3d1^NN) eIF3d1 was over-expressed. Phospho-dead eIF3d1 expression results in a significant decrease in CySC numbers (<i>N</i> ≥ 18 testes, * <i>P</i> < 0.05, ns <i>P</i> = 0.1150 (eIF3d1^WT) or <i>P</i> > 0.9999 (eIF3d1^DD), Kruskal-Wallis test). …”

Table 1_Imeglimin may affect hemoglobin A1c accuracy via prolongation of erythrocyte lifespan in patients with type 2 diabetes mellitus: insights from the INFINITY clinical trial.d... by Takeshi Osonoi (1951555)

“…</p>Results<p>The change in hemoglobin concentration at 6 months was not statistically significant (mean ± SD: −0.2 ± 0.9 g/dL; p = 0.23). …”

Datasheet1_Physiological characteristics of blood pressure responses after combined exercise in elderly hypertensive patients: a systematic review and meta-analysis.pdf by Zhiheng Li (525468)

“…</p>Results<p>In comparison to the control group (n = 194), individuals enrolled in the combined exercise group (n = 200) exhibited a notable decrease in both resting systolic blood pressure (SBP) [weighted mean difference (WMD) = −11.17 mm Hg, 95% confidence interval (CI) (−17.13, −5.22), Z = 3.68, P < 0.05] and diastolic blood pressure (DBP) [WMD = −5.93 mm Hg, 95% CI (−9.24, −2.61), Z = 3.51, P < 0.05]. …”

Data Sheet 1_Hemodynamic changes and their relationship with white matter hyperintensities in CSVD patients with cognitive impairment: a 4D flow study.pdf by Jiajun Cao (11560062)

“…</p>Results<p>The CSVD with CI population reported a statistically significant decrease in flow rate, blood flow velocity, and WSS, as well as an increase in PI, RI, CSF flow quantity, and velocity compared to age-matched cognitively healthy control participants. …”

Parallel bond model. by Yanan Sun (316649)

“…When the freeze-thaw cycle reached 80 times, the ringing counts changes significantly, showing a continuous accumulation trend. …”

Meso-parameters of numerical simulation. by Yanan Sun (316649)

“…When the freeze-thaw cycle reached 80 times, the ringing counts changes significantly, showing a continuous accumulation trend. …”

The simulated freeze-thaw cycle process. by Yanan Sun (316649)

“…When the freeze-thaw cycle reached 80 times, the ringing counts changes significantly, showing a continuous accumulation trend. …”

Supplementary Material for: TRENDS IN HOSPITAL DISCHARGES WITH PRIMARY DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS BY AGE AND SEX IN SPAIN by figshare admin karger (2628495)

“…Time series analysis showed a proportional decrease in younger women (p < 0.001) and a rising relative burden in older men (p < 0.001). …”

<b>Three-year follow-up after antiviral treatment in new-onset type 1 diabetes. Results from the Diabetes Virus Detection and Intervention trial.</b> by Ida M. Mynarek (20479470)

“…<p dir="ltr"><b>Objective</b></p><p dir="ltr">In the Diabetes Virus Detection and Intervention trial, antiviral treatment with pleconaril and ribavirin was shown to decrease the decline in endogenous C-peptide one year after diagnosis of type 1 diabetes in children and adolescents compared to placebo. …”

Supplementary file 1_Predicting HIV self-testing intentions among Chinese college students: a dual-model analysis integrating health belief constructs and machine learning prioriti... by Yan Jiang (12139)

“…Random forest modeling prioritized these psychological constructs (mean decrease Gini >2.5), identifying male students and arts majors as critical subpopulations requiring targeted intervention.…”