Table3_Modulation of left ventricular hypertrophy in spontaneously hypertensive rats by acetylcholinesterase and ACE inhibitors: physiological, biochemical, and proteomic studies.x... by Lucie Hejnova (19676323)

“…PYR enhanced BRS and improved vagal tone. There were no significant alterations in myocardial β-adrenergic and cholinergic signaling, with the exception of decreased forskolin-stimulated adenylyl cyclase (AC) activity in SHR rats, which was restored by TRA. …”

Table2_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”

Supplementary file 2_Longitudinal analysis of coal workers’ pneumoconiosis using enhanced resolution-computed tomography images: unveiling patterns in lung structure, function, and... by Ngan-Khanh Chau (17437641)

“…</p>Results<p>The study identified significant airway changes in angles, diameters, and geometry, with a decrease in normal lung tissue in the right upper lobe. …”

Distribution patterns of Platycodon grandiflorus from the last inter-glacial period to the future by ecological niche modeling by Chunjiao Li (19159480)

“…<p dir="ltr">Global climate change may represent a significant threat to the distribution and quality of medicinal plants, altering cultivation areas and compromising the quality of medical materials. …”

Table1_Cytochrome P450 VvCYP76F14 dominates the production of wine bouquet precursors in wine grapes.docx by Guangli Xia (19834830)

“…Site-directed mutation of 4 amino acid residues (I120L, L298V, E378G, and T389A) in VvCYP76F14 resulted in a significant decrease in VvCYP76F14 enzymatic activities, respectively. …”

Data Sheet 1_Dietary supplementation with proanthocyanidins and rutin alleviates the symptoms of type 2 diabetes mice and regulates gut microbiota.docx by Yue Gao (263086)

“…Background<p>Obesity and high fasting blood glucose (FBG) resulting from high-fat diets (HFDs) have emerged as significant public health concerns, garnering increasing attention. …”

Supplementary Material for: Cabergoline’s Promise in Endometriosis: Restoring Molecular Balance to Improve Reproductive Potential by figshare admin karger (2628495)

“…Results: Cabergoline treatment reduced the expression levels of VEGFR-2, FAK, PXN, ITGB3, and ITGAV, with ITGAV showing a statistically significant decrease (p = 0.0174). Hypomethylation of the VEGFR-2 promoter was observed in the treatment group (p = 0.3566). …”

Supplementary file 1_Is a single calibration for the TloadDback cognitive fatigue induction task reliable?.docx by Jeromy Michael Hrabovecky (21781397)

“…Comparisons across the 3 calibration sessions (χ²(2) = 34.1, p < 0.0001) showed a significant STD decrease (i.e., performance improvement) with the most salient between sessions 1 and 2 (t = 3.98, p = 0.0003^***). …”

Table 2_Burden of malignant neoplasm of bone and articular cartilage from 1990 to 2021 and its predictions to 2030 in China compared with world.xlsx by Cheng Chen (136164)

“…The burden prediction for MNBAC to 2030 showed that China would experience a more significant drop in incidence and mortality rates for MNBAC, along with a decrease in the incidence and mortality cases.…”

Data Sheet 3_Identification and validation of paraptosis-related biomarkers in recurrent miscarriage.pdf by Yunhui Wan (18795185)

“…ScRNA-seq analysis identified decidual natural killer (dNK) cells and macrophages as key cell types, with ELOA expression decreasing in dNK cells as their state changed, while in macrophages, expression followed a pattern of increase, decrease, and increase again.…”

Hsp90 mutation does not impact TDP-43 protein levels at the permissive temperature, 16°C. by Laura Garcia-Toscano (20477540)

“…</b> Mutant <i>hsp-90</i> does not decrease the levels of total and phosphorylated species of TDP-43 (pTDP-43). …”

Data_Sheet_1_Antibacterial effects of human mesenchymal stem cells and their derivatives: a systematic review.PDF by Adeline Castro Ramos (19736140)

“…Introduction<p>The growing problem of antimicrobial resistance (AMR) poses a significant challenge to public health; This is partly due to the lack of advancements in the development of novel antibiotics and the pressing need for alternative treatment options. …”

Costs of treating serious adverse effects of drugs used for treatment of obesity: comparison of selected European countries by Branislava Raičević (20102929)

“…Healthcare utilization and costs of treating ADRs to antiobesity drugs vary significantly among European countries. These differences should be considered when creating inputs for cost-effectiveness and budget impact models to decrease their uncertainty.…”

Image 2_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”

Table 1_Southward shift of winter wheat area intensifies regional water scarcity in the Beijing-Tianjin-Hebei region.docx by Qi Yan (287702)

“…Our findings reveal three distinct phases in wheat planting area changes, characterized by initial increase, subsequent decrease, and eventual stabilization. The southward shift in spatial distribution, evidenced by a 58-km migration of the planting centroids, led to significant water resource disparities. …”

Image 4_Molecular profiling of PYL gene family in sugar beet (Beta vulgaris L.) and BvPYL2/3 involved in ABA accumulation confers enhanced resistance to CLS (Cercospora Leaf Spot).... by Changmei Wu (22776269)

“…Transcriptome profiling showed that BvPYL2 displayed a stable constitutive expression profile in resistant and susceptible lines during infection, in contrast to BvPYL3, whose expression was marked by a significant decrease over the disease progression. Subcellular localization analysis revealed that both BvPYL2 and BvPYL3 localize to the plasma membrane, cytoplasm, and nucleus. …”

Data Sheet 1_Urinary microbiota changes among NMIBC patients during BCG therapy: comparing BCG responders and non-responders.docx by Toni Boban (20852165)

“…Patient inclusion criteria were male gender, no previous history of urothelial cancer, no other malignancies, no active infection, and no antibiotic usage for at least 20 days before the first BCG dose. We observed a significant decrease in biodiversity, measured by the Shannon Index, during the first week of therapy in 10 out of 12 patients (p=0.021). …”

DataSheet1_Subsurface mesoscale eddies in the east of the Philippines: three-dimensional biogeochemical structures and transports.docx by Ya-nan Ding (12006089)

“…SSEs also play an essential role in influencing chlorophyll (CHL) distribution, with SSAE (SSCE) causing an increase (decrease) in CHL at the euphotic zone (~110 m). In addition, the SSEs-induced NO₃, DO and CHL transport and their contributions to the changes in biogeochemical variables were also illustrated for the first time. …”

Data Sheet 1_Changes in monocyte subsets are associated with an increased risk of AAA and are surrogate markers for AAA morphology in patients with late-stage disease.pdf by Bianca Hamann (10837137)

“…The differences remained significant after adjusting for age, sex, and peripheral artery disease. …”

Image 4_Global trends of early-onset Parkinson’s disease from 1990 to 2021, and projections until to 2030: a systematic analysis of the global burden of disease study 2021.jpeg by Bingtao Hu (16784702)

“…The geographical disparities at regional and national level were evident. Significant disparities in EOPD burden by SDI were observed, exhibiting a worsening inequality over time. …”